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Volumn 57, Issue 3, 1999, Pages 332-341

Phosphatidylinositol 3-kinase and Akt protein kinase mediate IGF-I- and prosaptide-induced survival in Schwann cells

Author keywords

Apoptosis; Cell death; Extracellular regulated kinases (ERKs); Prosaposin; Saposin; Signaling

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; DNA FRAGMENT; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSAPOSIN; PROTEIN KINASE; SOMATOMEDIN C; WORTMANNIN;

EID: 0033179450     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19990801)57:3<332::AID-JNR5>3.0.CO;2-0     Document Type: Article
Times cited : (95)

References (51)
  • 1
    • 0032482374 scopus 로고    scopus 로고
    • Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B
    • Anderson KE, Coadwell J, Stephens LR, Hawkins PT. 1998. Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B. Curr Biol 8:684-691.
    • (1998) Curr Biol , vol.8 , pp. 684-691
    • Anderson, K.E.1    Coadwell, J.2    Stephens, L.R.3    Hawkins, P.T.4
  • 2
    • 0344900357 scopus 로고
    • Purification of rat schwann cells from cultures of peripheral nerve
    • Shahar A, de Vellis J, Vernadakis A, Haber B, editors. New York: Wiley-Liss, Inc.
    • Assouline JG, Bosch EP, Lim R. 1989. Purification of rat Schwann cells from cultures of peripheral nerve. In: Shahar A, de Vellis J, Vernadakis A, Haber B, editors. A dissection and tissue culture manual of the nervous system. New York: Wiley-Liss, Inc. p 247-250.
    • (1989) A Dissection and Tissue Culture Manual of the Nervous System , pp. 247-250
    • Assouline, J.G.1    Bosch, E.P.2    Lim, R.3
  • 3
    • 0028201079 scopus 로고
    • Control of oligodendrocyte number in the developing rat optic nerve
    • Barres BA, Raff MC. 1994 Control of oligodendrocyte number in the developing rat optic nerve. Neuron 12:935-942.
    • (1994) Neuron , vol.12 , pp. 935-942
    • Barres, B.A.1    Raff, M.C.2
  • 4
    • 0032500730 scopus 로고    scopus 로고
    • Bifurcation of lipid and protein kinase signals of PI3K to the protein kinases PKB and MAPK
    • Bondeva T, Pirola L, Bulgarelli-Leva G, Rubio I, Wetzker R, Wymann MP. 1998. Bifurcation of lipid and protein kinase signals of PI3K to the protein kinases PKB and MAPK. Science 282:293-295.
    • (1998) Science , vol.282 , pp. 293-295
    • Bondeva, T.1    Pirola, L.2    Bulgarelli-Leva, G.3    Rubio, I.4    Wetzker, R.5    Wymann, M.P.6
  • 5
    • 0025718514 scopus 로고
    • Transient IGF-I gene expression during the maturation of functionally related central projection neurons
    • Bondy CA. 1991. Transient IGF-I gene expression during the maturation of functionally related central projection neurons. J Neurosci 11:3442-3455.
    • (1991) J Neurosci , vol.11 , pp. 3442-3455
    • Bondy, C.A.1
  • 7
    • 0031906958 scopus 로고    scopus 로고
    • Prosaptide activates the MAPK pathway by a G-protein-dependent mechanism essential for enhanced sulfatide synthesis by Schwann cells
    • Campana WM, Hiraiwa M, O'Brien JS. 1998. Prosaptide activates the MAPK pathway by a G-protein-dependent mechanism essential for enhanced sulfatide synthesis by Schwann cells. FASEB J 12:307-314.
    • (1998) FASEB J , vol.12 , pp. 307-314
    • Campana, W.M.1    Hiraiwa, M.2    O'Brien, J.S.3
  • 9
    • 0032522924 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor dependent sympathetic neurons
    • Crowder RJ, Freeman RS. 1998. Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor dependent sympathetic neurons. J Neurosci 18:2933-2943.
    • (1998) J Neurosci , vol.18 , pp. 2933-2943
    • Crowder, R.J.1    Freeman, R.S.2
  • 10
    • 0029807471 scopus 로고    scopus 로고
    • Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors v-Src and v-Ha-ras in Sf9 and mammalian cells
    • Datta K, Bellacosa A, Chan TO, Tsichlis PN. 1996. Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors v-Src and v-Ha-ras in Sf9 and mammalian cells. J Biol Chem 271:30835-30839.
    • (1996) J Biol Chem , vol.271 , pp. 30835-30839
    • Datta, K.1    Bellacosa, A.2    Chan, T.O.3    Tsichlis, P.N.4
  • 11
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91:231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 12
    • 0029146540 scopus 로고
    • Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors
    • Dong Z, Brennana A, Liu N, Yarden Y, Lefkowitz G, Mirsky R, Jessen KR. 1995. Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors. Neuron 15:585-596.
    • (1995) Neuron , vol.15 , pp. 585-596
    • Dong, Z.1    Brennana, A.2    Liu, N.3    Yarden, Y.4    Lefkowitz, G.5    Mirsky, R.6    Jessen, K.R.7
  • 15
    • 0029039160 scopus 로고
    • Neurones and glial cells of the mouse sciatic nerve undergo apoptosis after injury in vivo and in vitro
    • Ekström PA. 1995. Neurones and glial cells of the mouse sciatic nerve undergo apoptosis after injury in vivo and in vitro. NeuroReport 6:1029-1032.
    • (1995) NeuroReport , vol.6 , pp. 1029-1032
    • Ekström, P.A.1
  • 16
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke TF, Yang S, Chan TO, Datta K, Kazlauskas A, Morrison, DK, Kaplan DR, Tsichlis PN. 1995. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81:727-736.
    • (1995) Cell , vol.81 , pp. 727-736
    • Franke, T.F.1    Yang, S.2    Chan, T.O.3    Datta, K.4    Kazlauskas, A.5    Morrison, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 17
    • 0029982572 scopus 로고    scopus 로고
    • Targeted disruption of the mouse sphingolipid activator protein gene: A complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids
    • Fujita N, Suzuki K, Vanier MT, Popko B, Maeda N, Klein A, Henseler M, Sandhoff K, Nakayasu H. 1996. Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids. Human Mol Genet 5:711-725.
    • (1996) Human Mol Genet , vol.5 , pp. 711-725
    • Fujita, N.1    Suzuki, K.2    Vanier, M.T.3    Popko, B.4    Maeda, N.5    Klein, A.6    Henseler, M.7    Sandhoff, K.8    Nakayasu, H.9
  • 18
    • 0029892754 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 suppression of tumor necrosis factor alpha mediated apoptosis requires ras and the activation of mitogen-activated protein kinase
    • Gardner A, Johnson G. 1996. Fibroblast growth factor-2 suppression of tumor necrosis factor alpha mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase. J Biol Chem 271:14560-14566.
    • (1996) J Biol Chem , vol.271 , pp. 14560-14566
    • Gardner, A.1    Johnson, G.2
  • 19
    • 0028796936 scopus 로고
    • Fibroblast growth factors and insulin like growth factors combine to promote survival of rat schwann cells precursors without induction of DNA synthesis
    • Gavrilovic J, Brennan A, Mirsky R, Jessen KJ. 1995. Fibroblast growth factors and insulin like growth factors combine to promote survival of rat Schwann cells precursors without induction of DNA synthesis. Eur J Neurosci 7:77-85.
    • (1995) Eur J Neurosci , vol.7 , pp. 77-85
    • Gavrilovic, J.1    Brennan, A.2    Mirsky, R.3    Jessen, K.J.4
  • 20
    • 0029813782 scopus 로고    scopus 로고
    • Axonal interactions regulate schwann cell apoptosis in developing peripheral nerve: Neuregulin receptors and the role of neuregulins
    • Grinspan JB, Marchionni MA, Reeves M, Coulaloglou M, Scherer SS. 1996. Axonal interactions regulate Schwann cell apoptosis in developing peripheral nerve: neuregulin receptors and the role of neuregulins. J Neurosci 16:6107-6118.
    • (1996) J Neurosci , vol.16 , pp. 6107-6118
    • Grinspan, J.B.1    Marchionni, M.A.2    Reeves, M.3    Coulaloglou, M.4    Scherer, S.S.5
  • 21
    • 0024420051 scopus 로고
    • Sphingolipid activator protein deficiency in a 16-week-old atypical Gaucher disease patient and his fetal sibling: Biochemical signs of combined sphigolipidoses
    • Harzer K, Paton BC, Poulos A, Kustermann-Kuhn B, Roggendorf W, Grisar T, Popp M. 1989. Sphingolipid activator protein deficiency in a 16-week-old atypical Gaucher disease patient and his fetal sibling: biochemical signs of combined sphigolipidoses. Eur J Pediatr 149:31-39.
    • (1989) Eur J Pediatr , vol.149 , pp. 31-39
    • Harzer, K.1    Paton, B.C.2    Poulos, A.3    Kustermann-Kuhn, B.4    Roggendorf, W.5    Grisar, T.6    Popp, M.7
  • 24
    • 0030971534 scopus 로고    scopus 로고
    • Cell death prevention, mitogen-activated protein kinase stimulation and increased sulfatide concentrations in Schwann cells and oligodendrocytes by prosaposin and prosaptides
    • Hiraiwa M, Taylor EM, Campana WM, Darin SJ, O'Brien JS. 1997b. Cell death prevention, mitogen-activated protein kinase stimulation and increased sulfatide concentrations in Schwann cells and oligodendrocytes by prosaposin and prosaptides. Proc Natl Acad Sci USA 94:4778-4781.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4778-4781
    • Hiraiwa, M.1    Taylor, E.M.2    Campana, W.M.3    Darin, S.J.4    O'Brien, J.S.5
  • 25
    • 0033152846 scopus 로고    scopus 로고
    • Prosaposin: A myelinotrophic protein that promotes expression of myelin constituents and is secreted after nerve injury
    • Hiraiwa M, Campana WM, Mizisin AP, Mohiuddin L, O'Brien JS. 1999. Prosaposin: a myelinotrophic protein that promotes expression of myelin constituents and is secreted after nerve injury. Glia 26:353-360.
    • (1999) Glia , vol.26 , pp. 353-360
    • Hiraiwa, M.1    Campana, W.M.2    Mizisin, A.P.3    Mohiuddin, L.4    O'Brien, J.S.5
  • 26
    • 0028199794 scopus 로고
    • The schwann cell precursor and its fate: A study of cell death and differentiation during gliogenesis in the rat embryonic nerves
    • Jessen KR, Brennan A, Morgan L, Mirsky R, Kent A, Hashimoto Y, Gavrilovic J. 1994. The Schwann cell precursor and its fate: a study of cell death and differentiation during gliogenesis in the rat embryonic nerves. Neuron 12:509-527.
    • (1994) Neuron , vol.12 , pp. 509-527
    • Jessen, K.R.1    Brennan, A.2    Morgan, L.3    Mirsky, R.4    Kent, A.5    Hashimoto, Y.6    Gavrilovic, J.7
  • 27
    • 0030844901 scopus 로고    scopus 로고
    • Glial growth factor rescues schwann cells of mechanoreceptors from denervation-induced apoptosis
    • Kopp DM, Trachtenberg JT, Thompson WJ. 1997. Glial growth factor rescues Schwann cells of mechanoreceptors from denervation-induced apoptosis. J Neurosci 17:6697-6706.
    • (1997) J Neurosci , vol.17 , pp. 6697-6706
    • Kopp, D.M.1    Trachtenberg, J.T.2    Thompson, W.J.3
  • 28
    • 0029996085 scopus 로고    scopus 로고
    • A hydrophillic peptide comprising 18 amino acid residues of the prosaposin sequence has neurotrophic activity in vitro and in vivo
    • Kotani Y, Matsuda S, Wen TC, Sakanaka M, Tanaka I, Maeda N, Kondoh K, Ueno S, Sano A. 1996. A hydrophillic peptide comprising 18 amino acid residues of the prosaposin sequence has neurotrophic activity in vitro and in vivo. J Neurochem 66:2197-2200.
    • (1996) J Neurochem , vol.66 , pp. 2197-2200
    • Kotani, Y.1    Matsuda, S.2    Wen, T.C.3    Sakanaka, M.4    Tanaka, I.5    Maeda, N.6    Kondoh, K.7    Ueno, S.8    Sano, A.9
  • 30
    • 0025151995 scopus 로고
    • Distribution of saposin proteins (sphingolipid activator proteins) in lysosomal storage and other diseases
    • Morimoto S, Yamamoto Y, O'Brien JS, Kishimoto Y. 1990. Distribution of saposin proteins (sphingolipid activator proteins) in lysosomal storage and other diseases. Anal Biochem 190:154-157.
    • (1990) Anal Biochem , vol.190 , pp. 154-157
    • Morimoto, S.1    Yamamoto, Y.2    O'Brien, J.S.3    Kishimoto, Y.4
  • 31
    • 0030988506 scopus 로고    scopus 로고
    • Apoptosis regulates the number of Schwann cells at the premyelinating stage
    • Nakao J, Shinoda J, Nakai, Y, Murase S, Uyemura K. 1997. Apoptosis regulates the number of Schwann cells at the premyelinating stage. J Neurochem 68:1853-1862.
    • (1997) J Neurochem , vol.68 , pp. 1853-1862
    • Nakao, J.1    Shinoda, J.2    Nakai, Y.3    Murase, S.4    Uyemura, K.5
  • 32
    • 0025897376 scopus 로고
    • Saposin proteins: Structure, function, and role in human lysosomal storage disorders
    • O'Brien JS, Kishimoto Y. 1991. Saposin proteins: structure, function, and role in human lysosomal storage disorders. FASEB J 5:301-308.
    • (1991) FASEB J , vol.5 , pp. 301-308
    • O'Brien, J.S.1    Kishimoto, Y.2
  • 35
    • 0031014651 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 inhibits apoptosis using the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathway
    • Parrizas M, Saltiel AR, LeRoith D. 1997 Insulin-like growth factor-1 inhibits apoptosis using the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathway. J Biol Chem 272:154-161.
    • (1997) J Biol Chem , vol.272 , pp. 154-161
    • Parrizas, M.1    Saltiel, A.R.2    Leroith, D.3
  • 36
    • 0030694175 scopus 로고    scopus 로고
    • Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons
    • Philpott KL, McCarthy MJ, Klippel A, Rubin LL. 1997. Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons. J Cell Biol 139:809-815.
    • (1997) J Cell Biol , vol.139 , pp. 809-815
    • Philpott, K.L.1    McCarthy, M.J.2    Klippel, A.3    Rubin, L.L.4
  • 37
    • 0029864731 scopus 로고    scopus 로고
    • Functional organization of saposin C. Definition of the neurotrophic and acid beta-glucosidase activation regions
    • Qi X, Qin W, Sun Y, Kondoh K, Grabowski G. 1996. Functional organization of saposin C. Definition of the neurotrophic and acid beta-glucosidase activation regions. J Biol Chem 271:6874-6880.
    • (1996) J Biol Chem , vol.271 , pp. 6874-6880
    • Qi, X.1    Qin, W.2    Sun, Y.3    Kondoh, K.4    Grabowski, G.5
  • 38
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • Raff MC. 1992. Social controls on cell survival and cell death. Nature 356:397-399.
    • (1992) Nature , vol.356 , pp. 397-399
    • Raff, M.C.1
  • 40
    • 0027285860 scopus 로고
    • Receptor stimulated accumulation of phoshatidylinositol (3,4,5)-triphosphate by G-protein mediated pathways in human myeloid derived cells
    • Stephens L, Eguinoa A, Corey S, Jackson T, Hawkins PT. 1993. Receptor stimulated accumulation of phoshatidylinositol (3,4,5)-triphosphate by G-protein mediated pathways in human myeloid derived cells. EMBO J 12:2265-2273.
    • (1993) EMBO J , vol.12 , pp. 2265-2273
    • Stephens, L.1    Eguinoa, A.2    Corey, S.3    Jackson, T.4    Hawkins, P.T.5
  • 41
    • 0029983932 scopus 로고    scopus 로고
    • Regulation of rat schwan cell P0 expression and DNA synthesis by insulin-like growth factors in vitro
    • Stewart HJ, Bradke F, Tabernero A, Morrell D, Jessen KR, Mirsky R. 1996. Regulation of rat Schwan cell P0 expression and DNA synthesis by insulin-like growth factors in vitro. Eur J Neurosci 8:553-564.
    • (1996) Eur J Neurosci , vol.8 , pp. 553-564
    • Stewart, H.J.1    Bradke, F.2    Tabernero, A.3    Morrell, D.4    Jessen, K.R.5    Mirsky, R.6
  • 43
    • 0030045796 scopus 로고    scopus 로고
    • Schwann cell apoptosis at developing neuromuscular junction is regulated by glial growth factor
    • Trachtenberg JT, Thompson WJ. 1996. Schwann cell apoptosis at developing neuromuscular junction is regulated by glial growth factor. Nature 379:174-177.
    • (1996) Nature , vol.379 , pp. 174-177
    • Trachtenberg, J.T.1    Thompson, W.J.2
  • 44
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich A, Schlessinger J. 1990. Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 45
    • 0029815526 scopus 로고    scopus 로고
    • Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival
    • Vemuri GS, McMorris FA. 1996. Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival. Development 122:2529-2537.
    • (1996) Development , vol.122 , pp. 2529-2537
    • Vemuri, G.S.1    McMorris, F.A.2
  • 46
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos CJ, Matter MF, Hui KY, Brown RF. 1994. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269:5241-5248.
    • (1994) J Biol Chem , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, M.F.2    Hui, K.Y.3    Brown, R.F.4
  • 47
    • 0029805072 scopus 로고    scopus 로고
    • Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor gene
    • Woods KA, Comacho-Hubner C, Savage MO, Clark AJL. 1996. Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor gene. N Engl J Med 335:1363-1367.
    • (1996) N Engl J Med , vol.335 , pp. 1363-1367
    • Woods, K.A.1    Comacho-Hubner, C.2    Savage, M.O.3    Clark, A.J.L.4
  • 48
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z, Dickens M, Raingeaud J, Davis R, Greenberg ME. 1995. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270:1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.4    Greenberg, M.E.5
  • 49
    • 0027374488 scopus 로고
    • Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells
    • Yano H, Nakanishi S, Kimura K, Hanai N, Saitoh Y, Fukui Y, Nonomura Y, Matsuda Y. 1993. Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem 268:25846-25856.
    • (1993) J Biol Chem , vol.268 , pp. 25846-25856
    • Yano, H.1    Nakanishi, S.2    Kimura, K.3    Hanai, N.4    Saitoh, Y.5    Fukui, Y.6    Nonomura, Y.7    Matsuda, Y.8
  • 50
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol 3-kinase in the prevention of apoptosis by nerve growth factor
    • Yao R, Cooper GM. 1995. Requirement for phosphatidylinositol 3-kinase in the prevention of apoptosis by nerve growth factor. Science 267:2003-2006.
    • (1995) Science , vol.267 , pp. 2003-2006
    • Yao, R.1    Cooper, G.M.2


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