In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitrogen-activated protien kinase-dependent activation of the transcription factor cAMP response element-binding protien

Circulation

Volumn 104, Issue 17, 2001, Pages 2088-2094

  Mehrhof, Felix B ^a   Müller, Frank Ulrich ^b   Bergmann, Martin W ^a   Li, Peifeng ^a   Wang, Yibin ^c   Schmitz, Wilhelm ^b   Dietz, Rainer ^a   Von Harsdorf, Rüdiger ^a,d  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Apoptosis; Growth factors; Hypoxia; Signal transduction

Indexed keywords

CELL PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN BAD; PROTEIN BCL 2; PROTEIN KINASE B; SOMATOMEDIN C; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL LEVEL; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EXPERIMENTAL MODEL; HEART MUSCLE CELL; HYPOXIC CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

EID: 0035940387     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc4201.097133     Document Type: Article

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