SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production

Journal of Neurochemistry

Volumn 82, Issue 6, 2002, Pages 1540-1548

  Li, Jinhe ^a   Pauley, Adele M ^a   Myers, Rick L ^a   Shuang, Rongqing ^a   Brashler, John R ^a   Yan, Riqiang ^a   Buhl, Allen E ^a   Ruble, Cara ^a   Gurney, Mark E ^a,b  

^a PFIZER INC   (United States)

^b DECODE GENETICS   (Iceland)

Author keywords

Alzheimer's disease; Amyloid peptide; Presenilin binding protein; SEL 10; Ubiquitination

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PROTEIN; GENE PRODUCT; PRESENILIN 1; PROTEIN SEL 10; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BINDING AFFINITY; BINDING KINETICS; CAENORHABDITIS ELEGANS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EGG LAYING; GENE LOCATION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL CYCLE PROTEINS; CELL LINE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; F-BOX PROTEINS; HELMINTH PROTEINS; HUMANS; KIDNEY; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PRESENILIN-1; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 0036736222     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01105.x     Document Type: Article

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