Olive oil phenolics: Effects on DNA oxidation and redox enzyme mRNA in prostate cells

British Journal of Nutrition

Volumn 88, Issue 3, 2002, Pages 225-234

  Quiles, José L ^a   Farquharson, Andrew J ^b   Simpson, David K ^b   Grant, Ian ^b   Wahle, Klaus W J ^b  

^a UNIVERSITY OF GRANADA   (Spain)

^b ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

DNA damage; Gene expression; Olive oil; Phenolic compounds

Indexed keywords

ANTIOXIDANT; CAFFEIC ACID; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; HYDROPEROXIDE; HYDROXYL GROUP; HYDROXYTYROSOL; MESSENGER RNA; OLIVE OIL; OXIDOREDUCTASE; PHENOL DERIVATIVE; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; TYROSOL;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CELLULAR PARAMETERS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG EFFECT; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LIPID OXIDATION; OXIDATION; OXIDATIVE STRESS; PROSTATE EPITHELIUM; SENSITIVITY ANALYSIS;

ANTIOXIDANTS; CAFFEIC ACIDS; CELL SURVIVAL; DIETARY FATS, UNSATURATED; DNA DAMAGE; GLUTATHIONE PEROXIDASE; HUMANS; LIPID PEROXIDATION; MALE; OXIDATION-REDUCTION; PHENOLS; PHENYLETHYL ALCOHOL; PLANT OILS; PROSTATE; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EUKARYOTA;

EID: 0036731647     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/BJN2002620     Document Type: Article

References (40)

1. Mitochondrial phospholipid hydroperoxide glutathione preoxidase plays a major role in preventing oxidative injure to cells
2. Antioxidant activity to tocopherols and phenolic compounds of virgin olive oil
3. Selective control of cytosolic glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase mRNA stability by selenium supply
4. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
5. Evolution of phenolic compounds in virgin olive oil during storage
6. Oxidative damage to DNA, do we have a reliable biomarker?
7. Inhibition of peroxynitrite dependent DNA base modification and tyrosine nitration by the extra virgin olive oil-derived antioxidant hydroxytyrosol
8. Lipid peroxidation and glutathione system in hyperlipemic rabbits, influence of olive oil administration
9. Hydroxytyrosol, a natural molecule occurring in olive oil, induces cytochrome c-dependent apoptosis
10. Development of a propidium iodide fluorescence assay for proliferation and cytotoxicity assays
11. Possible mechanisms for the putative anti-atherogenic and anti-tumorigenic effects of conjugated polyenoic fatty acids
12. 2+ in the presence of xylenol orange. Comparison with the TBA assay and an iodometric method
13. Eicosanoids in neoplasia
14. Inhibition of mammalian 5-lipoxygenase and cyclooxygenase by flavonoids and phenolics dietary additives. Relationship to antioxidant activity and to iron ion-reducing ability
15. Conventional cell culture media do not adequately supply cells with antioxidants and thus facilitate peroxide-induced genotoxicity
16. Biological effects of hydroxy-tyrosol, a polyphenol from olive oil endowed with antioxidant activity
17. The protective effect of the olive oil polyphenol (3,4-Dihydroxyphenyl)-ethanol counteracts reactive oxygen metabolite-induced cytotoxicity in Caco-2 cells
18. Transport mechanism and metabolism of olive oil hydroxytyrosol in Caco-2 cells
19. Antioxidant activity of 3,4-DHPEA-EA and protocateuuic acid, a comparative assessment with other olive oil biophenols
20. Tissue specific interactions of exercise, dietary fatty acids, and vitamin E in lipid peroxidation
21. Comparison of dietary saturated, monounsaturated, and polyunsaturated fatty acids on plasma lipids and lipoproteins in man
22. Effects of flavonoids on immune and inflammatory cell functions
23. Simple and hydrolyzable phenolic compounds in virgin olive oil. 1. Their extraction, separation and quantitative and semiquantitative evaluation by HPLC
24. Plant phenolics as inhibitors of mutational and precarcinogenic events
25. The antioxidant/anticancer potential of phenolic compounds isolated from olive oil
26. Inhibition of leukocyte leukotriene B4 production by an olive oil-derived phenol identified by mass spectrometry
27. Physical exercise affects the lipid profile of mitochondrial membranes in rats fed with virgin olive oil or sunflower oil
28. Vitamin E supplementation increases the stability and the in vivo antioxidant capacity of refined olive oil
29. Extra-Virgin more than refined olive oil increases the resistance of LDL to oxidation in free-living men with peripheral vascular disease
30. Strategies of antioxidant defense
31. Role of chemopreventers in human diet
32. Free radical-scavenging properties of olive oil polyphenols
33. Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages
34. Olive oils rich in natural catecholic phenols decrease isoprostane excretion in humans
35. The effect of minor constituents of olive oil on cardiovascular disease, new findings
36. Olive oil phenolics are dose-dependently absorbed in humans
37. Specific fatty acids and the risk of breast and prostate cancer, dietary intake