Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL

Journal of Clinical Investigation

Volumn 103, Issue 7, 1999, Pages 1067-1076

  Horton, Jay D ^a   Shimano, Hitoshi ^a   Hamilton, Robert L ^b   Brown, Michael S ^a   Goldstein, Joseph L ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LOW DENSITY LIPOPROTEIN RECEPTOR; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ARTICLE; CHOLESTEROL BLOOD LEVEL; ENDOPLASMIC RETICULUM; GENE DISRUPTION; GENE TARGETING; HYPERLIPIDEMIA; LIVER CELL; MEDIATOR RELEASE; MEMBRANE BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN DOMAIN; RECEPTOR GENE; TRANSCRIPTION REGULATION;

EID: 0032900336     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI6246     Document Type: Article

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