Lentiviral transduction of P140K MGMT into human CD34+ hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro

Molecular Therapy

Volumn 5, Issue 4, 2002, Pages 381-387

  Zielske, Steven P ^a   Gerson, Stanton L ^a  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE INHIBITOR; 6 O BENZYLGUANINE; CARMUSTINE; CD34 ANTIGEN; CYTOKINE; GUANINE NUCLEOTIDE BINDING PROTEIN; HEXADIMETHRINE BROMIDE; LENTIVIRUS VECTOR; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; VIRUS PROTEIN;

ARTICLE; BONE MARROW; CELL DIVISION; CELL PROTECTION; CELL SURVIVAL; CLONOGENIC ASSAY; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG RESISTANCE; GENE INSERTION; GENE MUTATION; GENE TRANSFER; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; VESICULAR STOMATITIS VIRUS; VIRAL GENE DELIVERY SYSTEM; VIRUS CONCENTRATION; VIRUS INFECTION;

INSERTION SEQUENCES; LENTIVIRUS; VECTORS; VESICULAR STOMATITIS VIRUS;

EID: 0036226607     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2002.0571     Document Type: Article

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