Retroviral transduction of a mutant methylguanine DNA methyltransferase gene into human CD34 cells confers resistance to O6-benzylguanine plus 1,3-bis(2-chloroethyl)-1-nitrosourea

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 24, 1996, Pages 14088-14093

  Reese, Jane S ^a   Koç, Omer N ^a   Lee, Keun Myoung ^a   Liu, Lili ^a   Allay, James A ^a,b   Phillips Jr , Weldon P ^a   Gerson, Stanton L ^a,c  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c BRB 3 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O BENZYLGUANINE; CARMUSTINE; CD34 ANTIGEN; DNA METHYLTRANSFERASE; GUANINE DERIVATIVE; METHYLGUANINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; CELL STRAIN K 562; CHO CELL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG RESISTANCE; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS;

ANIMALS; ANTIGENS, CD34; ANTINEOPLASTIC AGENTS; CARMUSTINE; CELL LINE; CELL SURVIVAL; CHO CELLS; CRICETINAE; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; GUANINE; HUMANS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; METHYLTRANSFERASES; MUTAGENESIS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; UNIDENTIFIED RETROVIRUS;

EID: 0030445950     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.24.14088     Document Type: Article

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