Oxygen sensing, HIF-1α stabilization and potential therapeutic strategies

Pflugers Archiv European Journal of Physiology

Volumn 443, Issue 4, 2002, Pages 503-507

  Hofer, T ^a   Wenger, R ^b   Gassmann, M ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF LÜBECK   (Germany)

Author keywords

MAP kinase; Prolyl hydroxylase; pVHL; Therapeutic angiogenesis; VEGF

Indexed keywords

2 OXOGLUTARIC ACID; AROMATIC HYDROCARBON RECEPTOR; CARRIER PROTEIN; GLUCOSE TRANSPORTER; HELIX LOOP HELIX PROTEIN; HYPOXIA INDUCIBLE FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE; VASCULOTROPIN;

ANGIOGENESIS; CAENORHABDITIS ELEGANS; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROXYLATION; HYPOXIA; NUCLEAR LOCALIZATION SIGNAL; OXYGEN TENSION; PRIORITY JOURNAL; REVIEW; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

ANIMALS; ANOXIA; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MAMMALS; OXYGEN; TRANSCRIPTION FACTORS;

EID: 0036187999     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-001-0759-8     Document Type: Review

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