Fission yeast Rad26 is a regulatory subunit of the Rad3 checkpoint kinase

Molecular Biology of the Cell

Volumn 13, Issue 2, 2002, Pages 480-492

  Wolkow, Tom D ^a   Enoch, Tamar ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE RAD3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN RAD26; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL CYCLE G2 PHASE; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SUBUNIT; EUKARYOTIC CELL; GENETIC STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; YEAST;

BLEOMYCIN; CATALYTIC DOMAIN; CELL CYCLE PROTEINS; DNA DAMAGE; FUNGAL PROTEINS; GENES, CDC; HYDROXYUREA; PHOSPHORYLATION; PROTEIN KINASES; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SIGNAL TRANSDUCTION;

EUKARYOTA; SCHIZOSACCHAROMYCES POMBE;

EID: 0036181181     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.01-03-0104     Document Type: Article

References (52)

1. Cell cycle checkpoint signaling through the ATM, and ATR kinases
2. DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe
3. Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast
4. Enhanced phosphorylation of p53 by ATM in response to DNA damage
5. The Schizosaccharomyces pombe rad3 checkpoint gene
6. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
7. Characterization of S. pombe Hus1. A PCNA-related protein that associates with Rad1 and Rad9
8. Requirement of sequences outside the conserved kinase domain of fission yeast Rad3p for checkpoint control
9. Checkpoint defects leading to premature mitosis also cause endoreplication of DNA in Aspergillus nidulans
10. Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway
11. A Rad3-Rad26 complex responds to DNA damage independently of other checkpoint proteins
12. Cell cycle checkpoints: Preventing an identity crisis
13. Fission yeast genes involved in coupling mitosis to completion of DNA replication
14. Cdc25 mitotic inducer targeted by Chk1 DNA damage checkpoint kinase
15. Fission yeast rad17: A homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins
16. Checkpoints: Controls that ensure the order of cell cycle events
17. Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family
18. The Aspergillus nidulans uvsB gene encodes an ATM-related kinase required for multiple facets of the DNA damage response
19. Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage
20. Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA
21. Saccharomyces Ku70, Mre11/Rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
22. S-phasespecific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe
23. Yeast checkpoint genes in DNA damage processing: Implications for repair and arrest
24. Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses
25. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
26. Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo, and in vitro
27. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
28. Mechanisms of caffeine-induced checkpoint override in fission yeast
29. Circular chromosome formation in a fission yeast mutant defective in two ATM homologues
30. The G2-phase DNA damage checkpoint
31. Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation
32. The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1, and is regulated by Mec1-dependent phosphorylation in budding yeast
33. LCD1. An essential gene involved in checkpoint control and regulation of the MEC1 signaling pathway in Saccharomyces cerevisiae
34. Checkpoint controls in Schizosaccharomyces pombe: Rad1
35. Inhibition of phosphoinositol 3-kinase related kinases by the radiosensitizing agent wortmannin
36. RuvAB acts at arrested replication forks
37. Ataxia-telangiectasia and the nijmegen breakage syndrome: Related disorders but genes apart
38. Replication factor C3 of S. pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpoints
39. +, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest
40. On the mechanism of action of bleomycin. Strand scission of DNA caused by bleomycin and its binding to DNA in vitro
41. A sliding clamp model for the Rad1 family of cell cycle checkpoint proteins
42. Functional interactions between BRAC1, and the checkpoint kinase ATR during genotoxic stress
43. Structure-based predictions of Rad1, Rad9, Hus1, and Rad17 participation in sliding clamp, and clamp-loading complexes
44. Visualization of plasmid replication intermediates containing reversed forks
45. Pie1, a protein interacting with Mec1, controls cell growth, and checkpoint responses in Saccharomyces cerevisiae
46. DNA damage. Chk1 and Cdc25, more than meets the eye
47. rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint
48. A DNA damage checkpoint meets the cell cycle engine
49. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae
50. Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: A gene required for the DNA damage checkpoint but not the replication checkpoint
51. Participation of ATM in insulin signaling through phosphorylation of elF-4E-binding protein 1
52. Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1