Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpoints

Molecular Biology of the Cell

Volumn 10, Issue 12, 1999, Pages 3991-4003

  Shimada, Midori ^a   Okuzaki, Daisuke ^a   Tanaka, Seiji ^a   Tougan, Takahiro ^a   Tamai, Katsuyuki K ^a,b   Shimoda, Chikashi ^b   Nojima, Hiroshi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b Osaka Prefecture University   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; FUNGAL DNA; HYDROXYUREA; MESYLIC ACID; MUTANT PROTEIN; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; CELL CYCLE G2 PHASE; CELL SYNCHRONIZATION; CHROMOSOME SEGREGATION; DNA DAMAGE; DNA REPLICATION; FUNGAL GENETICS; FUNGUS GROWTH; GENE DISRUPTION; GENE FUNCTION; GENE ISOLATION; MITOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; POINT MUTATION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RADIOSENSITIVITY; SCHIZOSACCHAROMYCES POMBE; TEMPERATURE SENSITIVE MUTANT;

FUNGI; MYXOGASTRIA; SCHIZOSACCHAROMYCES POMBE;

EID: 0032740539     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.10.12.3991     Document Type: Article

References (47)

1. Alfa, C., Fantes, P., Hyama, J., McLeod, M., and Warbrick, E. (1993). Experiments with Fission Yeast, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
2. Al-Khodairy, F., and Carr, A.M. (1992). DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe. EMBO J. 11, 1343-1350.
3. Al-Khodairy, F., Fotou, E., Sheldrick, K.S., Griffiths, D.J., Lehmann, A.R., and Carr, A.M. (1994). Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast. Mol. Biol. Cell 5, 147-160.
4. + gene as a new selectable marker for molecular genetic studies. Curr. Genet. 24, 491-495.
5. Araki, H., Leem, S.H., Phongdara, A., and Sugino, A. (1995). Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint. Proc. Natl. Acad. Sci. USA 92, 11791-11795.
6. Arroyo, M.P., and Wang, T.S.-F. (1998). Mutant PCNA alleles are associated with cdc phenotypes and sensitivity to DNA damage in fission yeast. Mol. Gen. Genet. 257, 505-518.
7. sp DNA structure checkpoint pathway. Curr. Opin. Genet. Dev. 7, 93-98.
8. Cullmann, G., Fien, K., Kobayashi, R., and Stillman, B. (1995). Characterization of the five replication factor C genes of Saccharomyces cerevisiae. Mol. Cell. Biol. 15, 4661-4671.
9. D'Urso, G., Grallert, B., and Nurse, P. (1995). DNA polymerase alpha, a component of the replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast. J. Cell Sci. 108, 3109-3118.
10. + encodes DNA polymerase epsilon and is required for chromosomal replication but not for the S phase checkpoint. Proc. Natl. Acad. Sci. USA 94, 12491-12496.
11. Edwards, R.J., and Carr, A.M. (1997). Analysis of radiation-sensitive mutants of fission yeast, Methods Enzymol. 283, 471-494.
12. Enoch, T., Carr, A.M., and Nurse, P. (1992). Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes & Dev. 6, 2035-2046.
13. Griffiths, D.J., Barbet, N.C., McCready, S., Lehmann, A.R., and Carr, A.M. (1995). Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins. EMBO J. 14, 5812-5823.
14. Grimm, C., Kohli, J., Murray, J., and Maundrell, K. (1988). Genetic engineering of Schizosaccharomyces pombe: a system for gene disruption and replacement using the ura4 gene as a selectable marker. Mol. Gen. Genet. 215, 81-86.
15. Hartwell, L.H., and Weinert, T.A. (1989). Checkpoints: controls that ensure the order of cell cycle events. Science 246, 629-634.
16. Hofmann, J.F., and Beach, D. (1994). cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis. EMBO J. 13, 425-434.
17. Hwang, L.H., Lau, L.F., Smith, D.L., Mistrot, C.A., Hardwick, K.G., Hwang, E.S., Amon, A., and Murray, A.W. (1998). Budding yeast Cdc20: a target of the spindle checkpoint [published erratum appears in Science 1998 May 29;280(5368):1331]. Science. 279, 1041-1044 (erratum [1.
18. +. Mol. Biol. Cell 6, 1793-1805.
19. + gene product couples S phase to START and mitosis. Cell 74, 371-382.
20. Lindsay, H.D., Griffiths, D.J., Edwards, R.J., Christensen, P.U., Murray, J.M., Osman, F., Walworth, N., and Carr, A.M. (1998). S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. Genes Dev. 12, 382-395.
21. Lydall, D., Nikolsky, Y., Bishop, D.K., and Weinert, T. (1996). A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Nature 383, 840-843.
22. + gene encoding a putative RNA helicase is essential for nitrogen starvation-induced G1 arrest and initiation of sexual development in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet. 244, 456-464.
23. McFarlane, R.J., Carr, A.M., and Price, C. (1997). Characterization of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function. Mol. Gen. Genet. 255, 332-340.
24. Murakami, H., and Okayama, H. (1995). A kinase from fission yeast responsible for blocking mitosis in S phase. Nature 374, 817-819.
25. Navas, T.A., Zhou, Z., and Elledge, S.J. (1995). DNA polymerase epsilon links the DNA replication machinery to the S phase checkpoint. Cell 80, 29-39.
26. Noskov, V.N., Araki, H., and Sugino, A. (1998). The RFC2 gene, encoding the third-largest subunit of the replication factor C complex, is required for an S-phase checkpoint in Saccharomyces cerevisiae. Mol. Cell. Biol. 18, 4914-4923.
27. Paulovich, A.G., and Hartwell, L.H. (1995). A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell 82, 841-847.
28. Reynolds, N., Fantes, P.A., and MacNeill, S.A. (1999). A key role for replication factor C in DNA replication checkpoint function in fission yeast. Nucleic Acids Res. 27, 462-469.
29. Rhind, N., and Russel, P. (1998). Mitotic DNA damage and replication checkpoints in yeast. Curr. Opin. Cell Biol. 10, 749-758.
30. Rowley, R., Subramani, S., and Young, P.G. (1992). Checkpoint controls in Schizosaccharomyces pombe: rad1. EMBO J. 11, 1335-1342.
31. Saka, Y., Esashi, F., Matsusaka, T., Mochida, S., and Yanagida, M. (1997). Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1. Genes Dev. 11, 3387-3400.
32. Saka, Y., Fantes, P., Sutani, T., McInerny, C., Creanor, J., and Yanagida, M. (1994). Fission yeast cut5 links nuclear chromatin and M phase regulator in the replication checkpoint control. EMBO J. 13, 5319-5329.
33. +. Cell 74, 383-393.
34. Sambrook, J., Fritsh, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
35. Shimomura, T., Ando, S., Matsumoto, K., and Sugimoto, K. (1998). Functional and physical interaction between Rad24 and Rfc5 in the yeast checkpoint pathways. Mol. Cell. Biol. 18, 5485-5491.
36. Siede, W., Friedberg, A.S., Dianova, I., and Friedberg, E.C. (1994). Characterization of G1 checkpoint control in the yeast Saccharomyces cerevisiae following exposure to DNA-damaging agents. Genetics 138, 271-281.
37. Siede, W., Friedberg, A.S., and Friedberg, E.C. (1993). RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 90 7985-7989.
38. Sugimoto, K., Ando, S., Shimomura, T., and Matsumoto, K. (1997). Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway. Mol. Cell. Biol. 17, 5905-5914.
39. Sugimoto, K., Shimomura, T., Hashimoto, K., Araki, H., Sugino, A., and Matsumoto, K. (1996). Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast. Proc. Natl. Acad. Sci. USA 93, 7048-7052.
40. Tanaka, H., Tanaka, K., Murakami, H., and Okayama, H. (1999). Fission yeast cdc24 is a replication factor C and proliferating cell nuclear antigen-interacting factor essential for S-phase completion. Mol. Cell. Biol. 19, 1038-1048.
41. Tsurimoto, T., Melendy, T., and Stillman, B. (1990). Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin. Nature 346, 534-539.
42. Tsurimoto, T., and Stillman, B. (1989). Purification of a cellular replication factor, RF-C, that is required for coordinated synthesis of leading and lagging strands during SV40 DNA replication in vitro. Mol. Cell. Biol. 9, 609-619.
43. Uchiyama, M., Galli, I., Griffiths, D.J., and Wang, T.S. (1997). A novel mutant allele of Schizosaccharomyces pombe rad26 defective in monitoring S-phase progression to prevent premature mitosis. Mol. Cell. Biol. 17, 3103-3115.
44. Walworth, N.C., and Bernards, R. (1996). rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint. Science 271, 353-356.
45. Weinert, T. (1998). DNA damage checkpoints update: getting molecular. Curr. Opin. Genet. Dev. 8, 185-193.
46. Weinert, T.A., and Hartwell, L.H. (1988). The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241, 317-322.
47. Willson, J., Wilson, S., Warr, N., and Watts, F.Z. (1997). Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint. Nucleic Acids Res. 25, 2138-2146.