Pie1, a protein interacting with mec1, controls cell growth and checkpoint responses in Saccharomyces cerevisiae

Molecular and Cellular Biology

Volumn 21, Issue 3, 2001, Pages 755-764

  Wakayama, T ^a   Kondo, T ^a   Ando, S ^a   Matsumoto, K ^a   Sugimoto, K ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; PROTEIN PIE1; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVITY; GENE CONTROL; GENE DELETION; GENE MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELL DIVISION; CONSERVED SEQUENCE; DNA DAMAGE; DNA PRIMERS; DNA REPAIR; DNA REPLICATION; FUNGAL PROTEINS; GENES, FUNGAL; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EUKARYOTA; SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES; SCHIZOSACCHAROMYCES POMBE;

EID: 0035138557     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.3.755-764.2001     Document Type: Article

References (50)

1. Identification of new elements involved in checkpoint and feedback controls in fission yeast
2. The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast
3. Isolation of yeast nuclei
4. Yeast nuclear envelope proteins cross-react with an antibody against mammalian pore complex proteins
5. Enhanced phosphorylation of p53 by ATM in response to DNA damage
6. The Schizosaccharomyces pombe rad3 checkpoint gene
7. mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development
8. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
9. Control of cell cycle arrest by Mec1sc/Rad3sp DNA structure checkpoint pathway
10. Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway
11. Nuclear targeting sequences - A consensus?
12. A Rad3-Rad26 complex responds to DNA damage independently of other checkpoint proteins
13. Cell cycle checkpoints: Preventing an identity crisis
14. MEC1-dependent phosphorylation of Rad9p in response to DNA damage
15. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
16. A novel Rad24 checkpoint protein complex closely related to replication factor C
17. The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene
18. Checkpoints: Controls that ensure the order of cell cycle events
19. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
20. An essential gene, ESR1, is required for mitotic cell growth, DNA repair, and meiotic recombination in Saccharomyces cerevisiae
21. The Atr and Arm protein kinases associate with different sites along meiotically pairing chromosomes
22. Role of a complex containing Rad 17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway
23. DNA damage checkpoint in budding yeast
24. The novel DNA damage checkpoint protein Ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast
25. Yeast checkpoint genes in DNA damage processing: Implications for repair and arrest
26. Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses
27. Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
28. TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
29. Rfc5, in cooperation with Rad24, controls DNA damage checkpoints throughout the cell cycle in Saccharomyces cerevisiae
30. The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast
31. Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p
32. LCDI: An essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae
33. Control of the DNA damage checkpoint by Chk1 and Rad53 protein kinases through distinct mechanisms
34. Regulation of RAD53 by the ATM-like kinase MEC1 and TEL1 in yeast cell cycle checkpoint pathways
35. A single ataxia telangiectasia gene with a product similar to PI-3 kinase
36. Functional and physical interaction between Rad24 and Rfc5 in the yeast checkpoint pathways
37. The DNA-dependent protein kinase
38. Checkpoint defects leading to premature mitosis also cause endoreplicadon of DNA in Aspergillus nidulans
39. Rfc5, replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway
40. Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways
41. Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint
42. A novel mutant allele of Schizosaccharomyces pombe rad26 defective in monotoring S-phase progression to prevent premature mitosis
43. The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage
44. Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint
45. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae
46. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
47. ATM-related genes: What do they tell us about functions of the human gene?
48. A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pool