-
2
-
-
0032727572
-
Comparative efficacy and safety of nimesulide and diclofenac in patients with acute shoulder, and a meta-analysis of controlled studies with nimesulide
-
(1999)
Rheumatology
, vol.38
, Issue.SUPPL. 1
, pp. 33-38
-
-
Wober, W.1
-
3
-
-
0035668839
-
Adverse drug reactions related to the use of NSA1Ds with a focus on nimesulide: Results of spontaneous reporting from a Northern Italian area
-
(2001)
Drug Saf
, vol.24
, Issue.14
, pp. 1081-1090
-
-
Conforti, A.1
Leone, R.2
Moretti, U.3
-
9
-
-
0031960403
-
Adverse effects of nonsteroidal anti-inflammatory drugs on the gastrointestinal system
-
(1998)
Ann Clin Lab Sci
, vol.28
, pp. 67-81
-
-
Fosslien, E.1
-
17
-
-
0030614703
-
Quantitative studies of the risk of serious hepatic injury in persons using nonsteroidal anti-inflammatory drugs
-
(1997)
Arthritis Rheum
, vol.40
, pp. 201-208
-
-
Walker, A.M.1
-
19
-
-
0032789796
-
New concepts in immunology relevant to idiosyncratic drug reactions: The 'danger hypothesis' and innate immune system
-
(1999)
Chem Res Toxicol
, vol.12
, pp. 387-395
-
-
Uetrecht, J.P.1
-
26
-
-
0033004051
-
Stereoselective and substrate-dependent inhibition of hepatic mitochondrial β-oxidation and oxidative phosphorylation by the non-steroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and ketorolac
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 837-844
-
-
Browne, G.S.1
Nelson, C.2
Nguyen, T.3
-
35
-
-
0035080391
-
Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver
-
(2001)
Hepatology
, vol.33
, pp. 783-791
-
-
Soroka, C.J.1
Lee, J.M.2
Azzaroli, F.3
-
43
-
-
0032939053
-
Reactive acyl glucuronides: Possible role in small intestinal toxicity induced by nonsteroidal anti-inflammatory drugs
-
(1999)
Toxic Subst Mech
, vol.18
, pp. 83-100
-
-
Boelsterli, U.A.1
-
49
-
-
0029101463
-
Cytotoxic activity of T cells and non-T cells from diclofenac-immunized mice against cultured syngeneic hepatocytes exposed to diclofenac
-
(1995)
Hepatology
, vol.22
, pp. 213-222
-
-
Kretz-Rommel, A.1
Boelsterli, U.A.2
-
57
-
-
0029758675
-
Nimesulide: A selective cyclooxygenase 2 inhibitor anti-inflammatory drug
-
(1996)
Drugs Today
, vol.32
, Issue.SUPPL. D
, pp. 1-32
-
-
Rabasseda, X.1
-
65
-
-
0031782660
-
An analysis from clinico-epidemiological data of the principal adverse events from the COX-2 selective NSAID, nimesulide, with particular reference to hepatic injury
-
(1998)
Inflammopharmacol
, vol.6
, pp. 203-221
-
-
Rainsford, K.D.1
-
77
-
-
0030826946
-
Attitude survey of adverse drug-reaction reporting by health care professionals across the European Union
-
(1997)
Eur J Clin Pharmacol
, vol.52
, pp. 423-427
-
-
Belton, K.J.1
-
80
-
-
0034950046
-
Drug-induced liver disorders: Implications for drug development and regulation
-
(2001)
Drug Saf
, vol.24
, Issue.7
, pp. 483-490
-
-
Kaplowitz, N.1
-
81
-
-
0005506651
-
-
Helsinn. Internal document. (Data on file.)
-
-
-
-
83
-
-
0028122558
-
Nimesulide: An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy
-
(1994)
Drugs
, vol.48
, pp. 431-454
-
-
Davis, R.1
Brogden, R.N.2
-
86
-
-
0026669915
-
Mechanism for the hepatotoxicity of the antiandrogen, nilutamide: Evidence suggesting that redox cycling of this nitroaromatic drug leads to oxidative stress in isolated hepatocytes
-
(1992)
J Pharmacol Exp Ther
, vol.263
, pp. 69-77
-
-
Fau, D.1
Berson, A.2
Eugene, D.3
-
90
-
-
0016722580
-
The mechanism of microsomal and mitochondrial nitroreductase: Electron spin resonance evidence for nitroaromatic free radical intermediates
-
(1975)
Biochemistry
, vol.14
, pp. 1626-1632
-
-
Mason, R.P.1
Holtzman, J.L.2
-
95
-
-
0005497373
-
-
Helsinn. Internal document no. 6026. (Data on file.)
-
-
-
-
100
-
-
0033768769
-
Tumor necrosis factor has positive and negative self regulatory feed back cycles centered around cAMP
-
(2000)
Int J Immunopharmacol
, vol.22
, pp. 1001-1006
-
-
Kast, R.E.1
-
101
-
-
0034175923
-
Non-steroidal anti-inflammatory drugs might also be pro-inflammatory by increasing tumor necrosis factor
-
(2000)
Biomed Pharmacother
, vol.54
, pp. 168-169
-
-
Kast, R.E.1
-
114
-
-
0029982516
-
Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNF alpha generation from human monocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer
-
(1996)
Br J Pharmacol
, vol.118
, pp. 649-658
-
-
Souness, J.E.1
Griffin, M.2
Maslen, C.3
-
116
-
-
0030751452
-
Effects of cAMP-phosphodiesterase isozyme inhibitor on cytokine production by lipopolysaccaride-stimulated human peripheral blood mononuclear cells
-
(1997)
Gen Pharmacol
, vol.29
, pp. 633-638
-
-
Yoshimura, T.1
Kurita, C.2
Nagao, T.3
-
118
-
-
0032727571
-
Gastrointestinal toxicity of non-steroidal anti-inflammatory drugs: The effect of nimesulide compared with naproxen on the human gastrointestinal tract
-
(1999)
Rheumatology
, vol.38
, Issue.SUPPL. 1
, pp. 24-32
-
-
Bjarnason, I.1
Thjodleifsson, B.2
-
122
-
-
0032722523
-
Relationship of nimesulide safety to its pharmacokinetics: Assessment of adverse reactions
-
(1999)
Rheumatology
, vol.38
, Issue.SUPPL. 1
, pp. 4-10
-
-
Rainsford, K.D.1
|