Non-steroidal anti-inflammatory drugs might also be pro-inflammatory by increasing tumor necrosis factor

Biomedicine and Pharmacotherapy

Volumn 54, Issue 3, 2000, Pages 168-169

  Kast, R E ^a  

^a NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 2; FLURBIPROFEN; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E; TUMOR NECROSIS FACTOR;

ADJUVANT ARTHRITIS; ANIMAL MODEL; ARTHRITIS; DRUG MECHANISM; HUMAN; HUMAN EXPERIMENT; IMMUNE SYSTEM; INFLAMMATION; LETTER; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; RHEUMATOID ARTHRITIS;

EID: 0034175923     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0753-3322(00)89050-2     Document Type: Letter

References (26)

1. Smith TJ. Cyclooxygenases as the principle targets for the actions of NASAIDs. Rheum Clinics N Amer 1998; 24 : 501-23.
2. Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van De Putte LB, et al. Cyclooxygenase in biology and disease. FASEB 1998; 12 : 1063-73.
3. Brouckaert P, Fiers W. TNF and the systemic inflammatory response syndrome. Curr Top Microbiol Imunol 1996; 216 : 167-87.
4. Bazzoni F, Beutler B. TNF ligand and receptor families. N Engl J Med 1996; 334 : 1717-25.
5. Saklatvala J. Intracellular signalling mechanism of interleukin and TNF: Possible targets for therapy. Br Med Bull 1995; 51 : 402-18.
6. Fournier T, Fadok V, Henson PM. TNF-alpha inversely regulates PG D2 and PG E2. Synergic action of cyclic AMP on cyclooxygenase 2 expression and PG E2 synthesis. J Biol Chem 1997; 272 : 31065-72.
7. Perkins DJ, Kniss DA. TNF-alpha promotes sustained cyclooxygenase 2 expression: Attenuation by dexamethasone and NSAIDs. Prostaglandins 1997; 54 : 727-43.
8. Yamamoto K, Arakawa T, Taketani Y, Takahashi Y, Hayashi Y, Ueda N, et al. TNF-alpha dependent induction of cyclooxygenase 2 mediated by NF kappa B and NF-IIL 6. Adv Exp Med Biol 1997; 407 : 185-9.
9. Wang B, Chen MZ. Effects of indomethacin on secretory function of synoviocytes from adjuvant arthritis rats. Int J Tissue React 1998; 20 : 91-4.
10. Sacca S, Agnello D, Sottocorno M, Lozza G, Monopoli A, Villa P, et al. NSAIDs increase TNF production in the periphery but not in the CNS of mice and rats. J Neurochem 1998; 71 : 2063-70.
11. Bertrand V, Guimbaud R, Tulliez M, Mauprivez C, Sogni P, Couturier D, et al. Increase in TNF-alpha production linked to toxicity of indomethacin for rat small intestine. Br J Pharmacol 1998; 124 : 1385-94.
12. Schumacher HR Jr, Meng Z, Sieck M, Zonay L, Clayburne G, Baker JF, et al. Effect of an NSAID on synovial fluid in osteoarthritis. J Rheumatol 1996; 23 : 1774-7.
13. Mansilla-Rosello A, Ferron-Orihuela JA, Ruiz-Cabello F, Garrote-Lara D, Fernandez-Mondejar E, Delgado-Carrasco ML. Differential effects of IL-beta and ibuprofen after endotoxic challenge in mice. J Surg Res 1997; 67 : 199-204.
14. Slomiany BL, Piotrowski J, Slomiany A. Induction of TNF-alpha and apoptosis in gastric mucosal injury by indomethacin: Effect of omperizole and ebrotidine. Scand J Gastroenterol 1997; 32 : 638-42.
15. Appleyard CB, McCafferty DM, Tigley AW, Swain MG, Wallace JL. TNF mediation of NSAID induced gastric damage: Role of leukocyte adherence. Amer J Physiol 1996; 270 : G42-8.
16. Endres S, Whitaker RE, Ghorbani R, Meydani SN, Dinarello CA. Oral aspirin and ibuprofen increase cytokine induced synthesis of IL-1 beta and of TNF-alpha ex vivo. Immunology 1996; 87 : 264-70.
17. Chou RC, Stinson MW, Noble BK, Spengler RN. Beta adrenergic receptor regulation of macrophage derived TNF production from rats with experimental arthritis. J Neuroimmunol 1996; 67 : 7-16.
18. Choi SS, Gatanaga M, Granger GA, Gatanaga T. Prostaglandin-E2 regulation of TNF receptor release in human monocytic THP-1 cells. Cell Immunol 1996; 170 : 178-84.
19. Seldon PM, Barnes PJ, Giembyez MA. Interleukin-10 does not mediate the inhibitory effect of PDE-4 inhibitors and other cAmp elevating drugs on LPS-induced TNF generation from human peripheral blood monocytes. Cell Biochem Biophys 1998; 29 : 179-201.
20. Ding SZ, Lam SK, Yuen ST, Wong BC, Hui WM, Ho J, et al. Prostaglandin, TNF-alpha and neutrophils: Causative relationship in indomethacin induced stomach injuries. Euro J Pharmacol 1998; 348 : 257-63.
21. Blackburn WD. Management of osteoarthritis and rheumatoid arthritis: Prospects and possibilities. Amer J Med 1996; 100 : 24S-30S.
22. Broks PM. Treatment of rheumatoid arthritis: From symptom relief to potential cure. Br J Rheumatol 1998; 37 : 1265-71.
23. Camussi G, Lupia E. The future of anti-TNF products in the treatment of rheumatoid arthritis. Drugs 1998; 55 : 613-20.
24. Goldenberg MM. Etanercept, a novel drug for the treatment of patients with severe, active rheumatoid arthritis. Clin Ther 1999; 21 : 75-87.
25. Davies NM. Review article: NSAID induced gastrointestinal permeability. Aliment Pharmacol Ther 1998; 12 : 303-20.
26. Mielants H, Goemaere S, 47 M, Schelstraete K, Goethals K, Maertens M, et al. Intestinal mucosal permeability in inflammatory rheumatic diseases. 1. Role of anti-inflammatory drugs. J Rheumatol 1991; 18 : 389-93.