Inhibition and uncoupling of oxidative phosphorylation by nonsteroidal anti-inflammatory drugs. Study in mitochondria, submitochondrial particles, cells, and whole heart

Biochemical Pharmacology

Volumn 57, Issue 7, 1999, Pages 743-752

  Moreno Sánchez, Rafael ^a,b   Bravo, Concepción ^a   Vásquez, César ^a   Ayala, Guadalupe ^c   Silveira, Luis H ^a   Martínez Lavín, Manuel ^a  

^a INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

^b UNIVERSIDAD MICHOACANA DE SAN NICOLÁS DE HIDALGO   (Mexico)

^c INSTITUTO NACIONAL DE SALUD PÚBLICA   (Mexico)

Author keywords

Mitochondria; NSAIDS; Oxidative phosphorylation; Uncoupling

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ADENOSINE TRIPHOSPHATE; DICLOFENAC; GLUTAMIC ACID; INDOMETACIN; MALIC ACID; MELOXICAM; NABUMETONE; NAPROXEN; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SUCCINIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HEART MUSCLE CONTRACTILITY; INOTROPISM; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; HEART; HYDROGEN-ION CONCENTRATION; LIVER; MEMBRANE POTENTIALS; MITOCHONDRIA, HEART; MITOCHONDRIA, LIVER; MYOCARDIUM; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; RATS; SUBMITOCHONDRIAL PARTICLES; UNCOUPLING AGENTS;

EID: 0344097396     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00330-X     Document Type: Article

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