Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

Leukemia

Volumn 12, Issue 9, 1998, Pages 1333-1337

  Kiyoi, H ^a   Towatari, M ^a   Yokota, S ^b   Hamaguchi, M ^a   Ohno, R ^c   Saito, H ^a   Naoe, T ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Acute myeloid leukemia; FLT3; Length mutation; Phosphorylation; Tandem duplication

Indexed keywords

TYROSINE;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ARTICLE; CODON; GENE DUPLICATION; GENE INSERTION; GENE MUTATION; MYELODYSPLASTIC SYNDROME; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SOMATIC MUTATION; TANDEM REPEAT;

EID: 0031686409     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401130     Document Type: Article

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