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Volumn 96, Issue 12, 2000, Pages 3907-3914

Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways

Author keywords

[No Author keywords available]

Indexed keywords

STAT5 PROTEIN;

EID: 0034554796     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.12.3907     Document Type: Article
Times cited : (522)

References (43)
  • 4
  • 5
    • 0027146421 scopus 로고
    • Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells
    • (1993) Cell , vol.75 , pp. 1157-1167
    • Lyman, S.D.1    James, L.2    Vanden Bos, T.3
  • 6
    • 0028203747 scopus 로고
    • Cloning of the human homologue of the murine flt3 ligand: A growth factor for early hematopoietic progenitor cells
    • (1994) Blood , vol.83 , pp. 2795-2801
    • Lyman, S.D.1    James, L.2    Johnson, L.3
  • 11
    • 0030002950 scopus 로고    scopus 로고
    • Expression of FLT3 receptor and response to FLT3 ligand by leukemic cells
    • (1996) Leukemia , vol.10 , pp. 588-599
    • Drexler, H.G.1
  • 15
    • 0028865727 scopus 로고
    • Effects of human FLT3 ligand on myeloid leukemia cell growth: Heterogeneity in response and synergy with other hematopoietic growth factors
    • (1995) Blood , vol.86 , pp. 4105-4114
    • Piacibello, W.1    Fubini, L.2    Sanavio, F.3
  • 16
    • 10544226868 scopus 로고    scopus 로고
    • Flt3 ligand stimulates proliferation and inhibits apoptosis of acute myeloid leukemia cells: Regulation of Bcl-2 and Bax
    • (1996) Blood , vol.88 , pp. 3987-3997
    • Lisovsky, M.1    Estrov, Z.2    Zhang, X.3
  • 20
    • 0031686409 scopus 로고    scopus 로고
    • Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product
    • (1998) Leukemia , vol.12 , pp. 1333-1337
    • Kiyoi, H.1    Towatari, M.2    Yokota, S.3
  • 21
    • 0032931560 scopus 로고    scopus 로고
    • Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia: The Children's Cancer and Leukemia Study Group, Japan
    • (1999) Leukemia , vol.13 , pp. 38-43
    • Iwai, T.1    Yokota, S.2    Nakao, M.3
  • 30
    • 16944365287 scopus 로고    scopus 로고
    • Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies: A study on a large series of patients and cell lines
    • (1997) Leukemia , vol.11 , pp. 1605-1609
    • Yokota, S.1    Kiyoi, H.2    Nakao, M.3
  • 31
    • 0030032943 scopus 로고    scopus 로고
    • Constitutive activation of c-kit in FMA3 murine mastocytoma cells caused by deletion of seven amino acids at the juxtamembrane domain
    • (1996) Blood , vol.87 , pp. 273-283
    • Tsujimura, T.1    Morimoto, M.2    Hashimoto, K.3
  • 32
  • 33
    • 0033557589 scopus 로고    scopus 로고
    • Activating mutation in the catalytic domain of c-kit elicits hematopoietic transformation by receptor self-association not at the ligand-induced dimerization site
    • (1999) Blood , vol.93 , pp. 1319-1329
    • Tsujimura, T.1    Hashimoto, K.2    Kitayama, H.3
  • 36
    • 0029810842 scopus 로고    scopus 로고
    • Phosphatidylinositol-3' kinase is not required for mitogenesis or internalization of the Flt3/Flk2 receptor tyrosine kinase
    • (1996) J Biol Chem , vol.271 , pp. 20075-20081
    • Beslu, N.1    LaRose, J.2    Casteran, N.3
  • 37
    • 0033582304 scopus 로고    scopus 로고
    • p85 subunit of P13 kinase does not bind to human Flt3 receptor, but associates with SHP2, SHIP, and a tyrosine-phosphorylated 100-kDa protein in Flt3 ligand-stimulated hematopoietic cells
    • (1999) Biochem Biophys Res Commun , vol.254 , pp. 440-445
    • Zhang, S.1    Broxmeyer, H.E.2
  • 41
    • 0034598830 scopus 로고    scopus 로고
    • Tandemduplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines
    • (2000) Oncogene , vol.19 , pp. 624-631
    • Hayakawa, F.1    Towatari, M.2    Kiyoi, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.