Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

Oncogene

Volumn 19, Issue 5, 2000, Pages 624-631

  Hayakawa, Fumihiko ^a   Towatari, Masayuki ^a   Kiyoi, Hitoshi ^a   Tanimoto, Mitsune ^a   Kitamura, Toshio ^b   Saito, Hidehiko ^a   Naoe, Tomoki ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

AML; Flt3; MAP kinase; STAT proteins; Tandem duplication

Indexed keywords

FLT3 LIGAND; INTERLEUKIN 3; MITOGEN ACTIVATED PROTEIN KINASE; STAT5 PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVATION; GENE DUPLICATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0034598830     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203354     Document Type: Article

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