Kinetics of inhibition of glutathione-mediated degradation of ferriprotoporphyrin IX by antimalarial drugs

Biochemical Pharmacology

Volumn 58, Issue 1, 1999, Pages 59-68

  Famin, Oleg ^a   Krugliak, Miriam ^a   Ginsburg, Hagai ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

4 aminoquinolines; Antimalarial drugs; Ferriprotoporphyrin IX degradation; Glutathione; Mode of action

Indexed keywords

4 AMINOQUINOLINE DERIVATIVE; AMODIAQUINE; ANTIMALARIAL AGENT; ARTEMISININ; CHLOROQUINE; GLUTATHIONE; HALOFANTRINE; HEMATIN; MEFLOQUINE; PYRONARIDINE; QUININE; VERAPAMIL;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION; DRUG MECHANISM; ERYTHROCYTE; HUMAN; HUMAN CELL; KINETICS; PARTITION COEFFICIENT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

AMODIAQUINE; ANIMALS; ANTIMALARIALS; CHLOROQUINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; GLUTATHIONE; HEMIN; HUMANS; KINETICS; PLASMODIUM FALCIPARUM;

EID: 0033168578     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00059-3     Document Type: Article

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