Deletion of the parasite-specific insertions and mutation of the catalytic triad in glutathione reductase from chloroquine-sensitive Plasmodium falciparum 3D7

Molecular and Biochemical Parasitology

Volumn 107, Issue 2, 2000, Pages 169-179

  Gilberger, Tim W ^a   Schirmer, R Heiner ^b   Walter, Rolf D ^a   Müller, Sylke ^a  

^a BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Catalytic mechanism; Chloroquine resistance; Glutathione reductase; Inhibitor design; Malaria; Plasmodium falciparum

Indexed keywords

CHLOROQUINE; GLUTATHIONE REDUCTASE;

ABSORPTION SPECTROSCOPY; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; CONTROLLED STUDY; DELETION MUTANT; IMMUNOBLOTTING; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTIMALARIALS; CATALYSIS; CHLOROQUINE; FLAVINS; GENE DELETION; GLUTATHIONE REDUCTASE; KINETICS; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; POINT MUTATION; SPECTRUM ANALYSIS;

FELIS CATUS; PLASMODIUM FALCIPARUM;

EID: 0034655152     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(00)00188-2     Document Type: Article

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