Binding-induced activation of DNA alkylation by duocarmycin SA: Insights from the structure of an indole derivative - DNA adduct

Journal of the American Chemical Society

Volumn 121, Issue 24, 1999, Pages 5645-5652

  Schnell, Jason R ^a   Ketchem, Randal R ^a   Boger, Dale L ^a   Chazin, Walter J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; DUOCARMYCIN SA; INDOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING SITE; CATALYSIS; DNA ALKYLATION; DNA SEQUENCE; DRUG DNA BINDING;

EID: 0033597629     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja983556j     Document Type: Article

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