Damage-induced apoptosis in intestinal epithelia from bcl-2-null and bax-null mice: Investigations of the mechanistic determinants of epithelial apoptosis in vivo

Oncogene

Volumn 18, Issue 51, 1999, Pages 7287-7293

  Pritchard, D Mark ^a,b   Potten, Christopher S ^b   Korsmeyer, Stanley J ^c   Roberts, Steven ^b   Hickman, John A ^a  

^a School of Biological Sciences   (United Kingdom)

^b CHRISTIE HOSPITAL   (United Kingdom)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

5 Fluorouracil; Apoptosis; bax; bcl 2; Intestinal epithelia; irradiation

Indexed keywords

FLUOROURACIL; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; GAMMA IRRADIATION; GENE EXPRESSION; INTESTINE CRYPT; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

EID: 0033518139     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203150     Document Type: Article

References (38)

1. Canman CE, Gilmer TM, Coutts SB and Kastan MB. (1995). Genes Dev., 9, 600-611.
2. Chresta CM, Masters JRW and Hickman JA. (1996). Cancer Res., 56, 1834-1841.
3. Clarke AR, Gledhill S, Hooper ML, Bird CC and Wyllie AH. (1994). Oncogene, 9, 1767-1773.
4. Clarke AR, Howard LA, Harrison DJ and Winton DJ. (1997). Oncogene, 14, 2015-2018.
5. Dive C and Hickman JA. (1991). Br. J. Cancer, 64, 192-196.
6. Hague A, Moorghen M, Hicks D, Chapman M and Paraskeva C. (1994). Oncogene, 9, 3367-3370.
7. Hockenberry DM, Zutter M, Hickey W, Nahm M and Korsmeyer SJ. (1991). Proc. Natl. Acad. Sci. USA, 88, 6961-6965.
8. Ijiri K and Potten CS. (1983). Br. J. Cancer, 47, 175-185.
9. Ijiri K and Potten CS. (1987). Br. J. Cancer, 55, 113-123.
10. Knudson CM, Tung KSK, Tourtellotte WG, Brown GAJ and Korsmeyer SJ. (1995). Science, 270, 96-99.
11. Krajewski S, Tanaka S, Takayama S, Schibler MJ, Fenton W and Reed JC. (1993). Cancer Res., 53, 4701-4714.
12. Krajewski S, Krajewska M, Shabaik A, Miyashita T, Wang HG and Reed JC. (1994). Am. J. Path., 115, 1323-1336.
13. Lamb JR and Friend SH. (1997). Nature Med, 3, 962-963.
14. McCurrach ME, Connor TMF, Knudson CM, Korsmeyer SJ and Lowe SW. (1997). Proc. Natl. Acad Sci. USA, 94, 2345-2349.
15. Merritt AJ, Potten CS, Kemp CJ, Hickman JA, Balmain A, Lane DP and Hall PA. (1994). Cancer Res., 54, 614-617.
16. Merritt AJ, Potten CS, Watson AJM, Loh DY, Nakayama K, Nakayama K and Hickman JA. (1995). J. Cell Science, 108, 2261-2271.
17. Merritt AJ, Jones LS and Potten CS. (1996). In: Techniques in Apoptosis. Cotter TG and Martin SJ. (eds). Portland Press Ltd. London. pp. 269-300.
18. Merritt AJ, Allen TD, Potten CS and Hickman JA. (1997). Oncogene, 14, 2759-2766.
19. Miyashita T and Reed JC. (1995). Cell, 80, 293-299.
20. Nakayama K, Nakayama K, Negishi I, Kuidba K, Shinkai Y, Louie MC, Fields LE, Lucas PJ, Stewart V, Alt FW and Loh DY. (1993). Science, 261, 1584-1588.
21. Nakayama K, Nakayama K, Negishi I, Kuida K, Sawa H and Loh DY. (1994). Proc. Natl. Acad. Sci. USA, 91, 3700-3704.
22. Perez GI, Robles R, Knudson CM, Korsmeyer SJ and Tilly JL. (1997). Nature Medicine, 3, 1228-1232.
23. Potten CS (1977) Nature, 269, 518-521.
24. Potten CS. (1990). Int. J. Rad. Biol., 58, 925-973.
25. Potten CS. (1992). Cancer Metastasis Rev., 11, 179-195.
26. Potten CS. (1996). Br. J. Cancer, 74, 1743-1748.
27. Potten CS and Grant HK. (1998). Br. J. Cancer, 78, 993-1003.
28. Potten CS, Owen G and Roberts SA. (1990). Int. J. Radiat. Biol., 57, 185-199.
29. Potten CS, Booth C and Pritchard DM. (1997). Int. J. Exp. Path., 78, 219-243.
30. Pritchard DM, Watson AJ, Potten CS, Jackman AL and Hickman JA. (1997). Proc. Natl. Acad. Sci. USA, 94, 1795-1799.
31. Pritchard DM, Potten CS and Hickman JA. (1998). Cancer Res., 58, 5453-5465.
32. Rampino N, Yamamoto H, Ionov Y, Li Y, Sawai H, Reed JC and Perucho M. (1997). Science, 275, 967-969.
33. Reed JC. (1999). In: Apoptosis and Cancer Chemotherapy. Hickman JA and Dive C. (eds). Humana Press: Totowa, NJ. pp. 99-116.
34. Salvesen GS and Dixit VM. (1997). Cell, 91, 443-446.
35. Simms LA, Radford-Smith G, Biden, KG, Buttenshaw R, Cummings M, Jass JR, Young J, Meltzer SJ and Leggett BA. (1998). Oncogene, 17, 2003-2008.
36. Watson AJM, Merritt AJ, Jones LS, Askew JN, Anderson E, Becciolini A, Balzi M, Potten CS and Hickman JA. (1996). Br. J. Cancer, 73, 889-895.
37. Wilson JW and Potten CS. (1996). Apoptosis, 1, 183-190.
38. Yin C, Knudson CM, Korsmeyer SJ and Van Dyke T. (1997). Nature, 385, 637-640.