Effector lymphocytes in autoimmunity

Current Opinion in Immunology

Volumn 13, Issue 6, 2001, Pages 663-669

  Santamaria, P ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CELL RECEPTOR; CYTOKINE; GRANZYME B; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

AUTOIMMUNE DISEASE; AUTOIMMUNITY; CELL INTERACTION; CELL MEDIATED CYTOTOXICITY; CELL SUBPOPULATION; CELL SURFACE; CELL TYPE; EFFECTOR CELL; HUMAN; IMMUNE RESPONSE; KINETICS; LYMPHOCYTE; NONHUMAN; REVIEW; TARGET CELL; TISSUE INJURY;

EID: 0035546053     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(01)00276-X     Document Type: Review

References (72)

1. The nonobese diabetic mouse as a model of autoimmune diabetes: Immune disregulation gets the NOD
2. Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library
3. Progression of autoimmune diabetes driven by avidity maturation of a T-cell population
4. + T cells from non-obese diabetic mice use highly homologous T cell receptor α chain CDR3 sequences
5. + T cells expressing identical endogenous TCRα chains
6. Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice
7. Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor α chain gene rearrangement
8. + T cell response against one peptide/MHC complex in autoimmune diabetes
9. Expansion of the antigenic repertoire of a single T cell receptor upon T-cell activation
10. In situ characterization of autoimmune phenomenon: An expression of HLA molecules in the pancreas of diabetic insulinitis
11. Recurrent diabetes mellitus in the pancreas iso- and allograft
12. Inflammatory cytokine regulation of Fas-mediated apoptosis in thyroid follicular cells
13. h4 and NOD mice
14. Tolerance and autoimmunity in TCR transgenic mice specific for myelin basic protein
15. k mice
16. + T-cells are encephalitogenic and produce severe disease in C57BL/6 mice
17. + T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
18. Pro-apoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
19. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
20. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
21. TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation
22. + T cell killing of antigen-presenting macrophages
23. Different modes of pathogenesis in T-cell-dependent autoimmunity: Clues from two TCR transgenic systems
24. Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
25. Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity
26. + T cell-mediated insulin-dependent diabetes mellitus
27. Virus-induced autoimmune diabetes: Most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes
28. Mechanisms of beta cell death in diabetes: A minor role for CD95
29. In autoimmune diabetes the transition from benign to pernicious insulitis requires an inslet cell response to tumor necrosis factor α
30. Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice
31. Significant role for Fas in the pathogenesis of autoimmune diabetes
32. The role of Fas in autoimmune diabetes
33. + T lymphocytes in transgenic nonobese diabetic mice
34. + T-lymphocytes
35. Fas and Fas ligand expression in inflamed islets in pancreas sections of patients with recent-onset Type I diabetes mellitus
36. + T cells by a self-derived peptide
37. Impaired binding of perforin on the surface of tumor cells is a cause of target cell resistance against cytotoxic effector cells
38. Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis
39. Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system
40. Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis
41. Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis
42. A targeted DNA vaccine encoding fas ligand defines its dual role in the regulation of experimental autoimmune encephalomyelitis
43. Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis
44. Fas and Fas ligand expressed on cells of the immune system, not on the target tissue, control induction of experimental autoimmune uveitis
45. The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity
46. Fas and Fas ligand mutations inhibit autoantibody production in pristane-induced lupus
47. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis
48. Fas ligand expression in thyroid carcinomas: A potential mechanism for immune evasion
49. Functional fas ligand expresion in thyrocytes from patients with Graves' disease
50. T cell-mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis
51. The temporal importance of TNFα expression in the development of diabetes
52. Monitoring gene expression of TNFR family members by beta-cells during development of autoimmune diabetes
53. Tumor necrosis factor receptor-1 is critically involved in the development of experimental autoimmune myasthenia gravis
54. Severity of symptoms and demyelination in MOG-induced EAE depends on TNFR1
55. 35-55-induced experimental autoimmune encephalomyelitis
56. Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: Implications for pathogenesis and therapy of autoimmune demyelination
57. TNF-induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53
58. hi T cells
59. TNFRSF1A mutations and autoinflammatory syndromes
60. Etanercept in children with polyarticular juvenile rheumatoid arthritis
61. Mechanisms of disease: Cytokine pathways and joint inflammation in rheumatoid arthritis
62. Distinction between interleukin-1-induced necrosis and apoptosis of islet cells
63. Unusual resistance of ALR/Lt mouse beta cells to autoimmune destruction: Role for beta cell-expressed resistance determinants
64. TRAIL death pathway expression and induction in thyroid follicular cells
65. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression
66. Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis
67. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
68. Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in crohn's disease and experimental colitis in vivo
69. Genetic models for CNS inflammation
70. Oxazolone colitis: A murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4
71. Alteration of interleukin 4 production results in the inhibition of T helper type 2 cell-dominated inflammatory bowel disease in T cell receptor α chain-deficient mice
72. IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis