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Volumn 164, Issue 5, 2000, Pages 2523-2532

Significant role for Fas in the pathogenesis of autoimmune diabetes

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; LIGAND;

EID: 0034162513     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.5.2523     Document Type: Article
Times cited : (105)

References (69)
  • 1
    • 0029954214 scopus 로고    scopus 로고
    • Insulin-dependent diabetes mellitus
    • Tisch, R., and H. McDevitt. 1996. Insulin-dependent diabetes mellitus. Cell 85: 291.
    • (1996) Cell , vol.85 , pp. 291
    • Tisch, R.1    McDevitt, H.2
  • 2
    • 0028922437 scopus 로고
    • Genetic control of autoimmune diabetes in the NOD mouse
    • Wicker, L. S., J A. Todd,. and L. B. Peterson. 1995. Genetic control of autoimmune diabetes in the NOD mouse. Annu. Rev. Immunol. 13:179.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 179
    • Wicker, L.S.1    Todd, J.A.2    Peterson, L.B.3
  • 3
    • 43949152435 scopus 로고
    • Prevention of diabetes in the NOD mouse: Implication for therapeutic intervention in human disease
    • Bowman, M. A., E. H. Leiter, and M. A. Atkinson. 1994. Prevention of diabetes in the NOD mouse: implication for therapeutic intervention in human disease. Immunol. Today 15:115.
    • (1994) Immunol. Today , vol.15 , pp. 115
    • Bowman, M.A.1    Leiter, E.H.2    Atkinson, M.A.3
  • 4
    • 0030937468 scopus 로고    scopus 로고
    • Apoptosis is the mode of β-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse
    • O'Brien, B. A., B. V. Harmon, D. P. Cameron, and D. J. Allan. 1997. Apoptosis is the mode of β-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse. Diabetes 46:750.
    • (1997) Diabetes , vol.46 , pp. 750
    • O'Brien, B.A.1    Harmon, B.V.2    Cameron, D.P.3    Allan, D.J.4
  • 5
    • 0030731917 scopus 로고    scopus 로고
    • Nitric oxide primes pancreatic β cells for Fas-mediated destruction in insulin-dependent diabetes mellitus
    • Stassi, G., R. D. Maria, G. Trucco, W. Rudert, R. Testi, A. Galluzzo, C. Giordano, and M. Trucco. 1997. Nitric oxide primes pancreatic β cells for Fas-mediated destruction in insulin-dependent diabetes mellitus. J. Exp. Med. 186:1193.
    • (1997) J. Exp. Med. , vol.186 , pp. 1193
    • Stassi, G.1    Maria, R.D.2    Trucco, G.3    Rudert, W.4    Testi, R.5    Galluzzo, A.6    Giordano, C.7    Trucco, M.8
  • 8
    • 1842289172 scopus 로고    scopus 로고
    • Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
    • Kagi, D., B. Odermatt, P. Seiler, R. M. Zinkernagel, T. W. Mak, and H. Hengartner. 1997. Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice. J. Exp. Med. 186:989.
    • (1997) J. Exp. Med. , vol.186 , pp. 989
    • Kagi, D.1    Odermatt, B.2    Seiler, P.3    Zinkernagel, R.M.4    Mak, T.W.5    Hengartner, H.6
  • 9
    • 0027990811 scopus 로고
    • Effect of tumor necrosis factor α on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process
    • Yang, X., R. Tisch, S. M. Singer, Z. A. Cao, R. S. Liblau, R. D. Schreiber, and H. O. McDevitt. 1994. Effect of tumor necrosis factor α on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process. J. Exp. Med. 180:995.
    • (1994) J. Exp. Med. , vol.180 , pp. 995
    • Yang, X.1    Tisch, R.2    Singer, S.M.3    Cao, Z.A.4    Liblau, R.S.5    Schreiber, R.D.6    McDevitt, H.O.7
  • 10
    • 0033561630 scopus 로고    scopus 로고
    • TNF receptor 1-dependent β cell toxicity as an effector pathway in autoimmune diabetes
    • Kagi, D., A. Ho, B. Odermatt, A. Zakarian, P. S. Ohashi, and T. W. Mak. 1999. TNF receptor 1-dependent β cell toxicity as an effector pathway in autoimmune diabetes. J. Immunol. 162:4598.
    • (1999) J. Immunol. , vol.162 , pp. 4598
    • Kagi, D.1    Ho, A.2    Odermatt, B.3    Zakarian, A.4    Ohashi, P.S.5    Mak, T.W.6
  • 11
    • 0033526068 scopus 로고    scopus 로고
    • In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor α
    • Pakala, S. V., M. Chivetta, C. B. Kelly, and J. D. Katz. 1999. In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor α. J. Exp. Med. 189:1053.
    • (1999) J. Exp. Med. , vol.189 , pp. 1053
    • Pakala, S.V.1    Chivetta, M.2    Kelly, C.B.3    Katz, J.D.4
  • 12
    • 0032214715 scopus 로고    scopus 로고
    • Local expression of TNF or in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens
    • Green, E. A., E. E. Eynon, and R. A. Flavell. 1998. Local expression of TNF or in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens. Immunity 9:733.
    • (1998) Immunity , vol.9 , pp. 733
    • Green, E.A.1    Eynon, E.E.2    Flavell, R.A.3
  • 13
    • 0029834839 scopus 로고    scopus 로고
    • Local expression of transgene encoded TNF or in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells
    • Grewal, I. S., K. D. Grewal, F. S. Wong, D. E. Picarella, C. A. Janeway, Jr., and R. A. Flavell. 1996. Local expression of transgene encoded TNF or in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells. J. Exp. Med. 184:1963.
    • (1996) J. Exp. Med. , vol.184 , pp. 1963
    • Grewal, I.S.1    Grewal, K.D.2    Wong, F.S.3    Picarella, D.E.4    Janeway C.A., Jr.5    Flavell, R.A.6
  • 14
    • 0032932324 scopus 로고    scopus 로고
    • β-Cell destruction in NOD mice correlates with Fas (CD95) expression on β-cells and proinflammatory cytokine expression in islets
    • Suarez-Pinzon, W., O. Sorensen, R. C. Bleackley, J. F. Elliott, R. V. Rajotte, and A. Rabinovitch. 1999. β-Cell destruction in NOD mice correlates with Fas (CD95) expression on β-cells and proinflammatory cytokine expression in islets. Diabetes 48:21.
    • (1999) Diabetes , vol.48 , pp. 21
    • Suarez-Pinzon, W.1    Sorensen, O.2    Bleackley, R.C.3    Elliott, J.F.4    Rajotte, R.V.5    Rabinovitch, A.6
  • 15
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga R., C. I. Brannan, N. G. Copeland, N. A. Jenkins, and S. Nagata. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314.
    • (1992) Nature , vol.356 , pp. 314
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 16
    • 0028928654 scopus 로고
    • Massive upregulation of the Fas ligand in lpr and gld mice: Implication for Fas regulation and the graft-versus-host disease-like wasting syndrome
    • Chu, J. L., P. Ramos, A. Rosendorff, J. Nikolic-Zugic, E. Lacy, A. Matsuzawa, and K. B. Elkon. 1995. Massive upregulation of the Fas ligand in lpr and gld mice: implication for Fas regulation and the graft-versus-host disease-like wasting syndrome. J. Exp. Med. 181:393.
    • (1995) J. Exp. Med. , vol.181 , pp. 393
    • Chu, J.L.1    Ramos, P.2    Rosendorff, A.3    Nikolic-Zugic, J.4    Lacy, E.5    Matsuzawa, A.6    Elkon, K.B.7
  • 17
    • 0032506224 scopus 로고    scopus 로고
    • Mechanisms of β cell diabetes: A minor role for CD95
    • Allison, J., and A. Strasser. 1998. Mechanisms of β cell diabetes: a minor role for CD95. Proc. Natl. Acad Sci. USA 95:13818.
    • (1998) Proc. Natl. Acad Sci. USA , vol.95 , pp. 13818
    • Allison, J.1    Strasser, A.2
  • 18
    • 0028786340 scopus 로고
    • Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping
    • Ikegami, H., S. Makino, E. Yamato, Y. Kawaguchi, H. Ueda, T. Sakamoto, K. Takekawa, and T. Ogihara. 1995. Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping. J. Clin. Invest. 96:1936.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1936
    • Ikegami, H.1    Makino, S.2    Yamato, E.3    Kawaguchi, Y.4    Ueda, H.5    Sakamoto, T.6    Takekawa, K.7    Ogihara, T.8
  • 20
    • 0022492875 scopus 로고
    • Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice
    • Wicker, L. S., B. J. Miller, and Y. Mullen. 1986. Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice. Diabetes 35:855.
    • (1986) Diabetes , vol.35 , pp. 855
    • Wicker, L.S.1    Miller, B.J.2    Mullen, Y.3
  • 22
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse, T. J., and J. A. Todd. 1996. Genetic analysis of autoimmune disease. Cell 85:311.
    • (1996) Cell , vol.85 , pp. 311
    • Vyse, T.J.1    Todd, J.A.2
  • 25
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
    • Takahashi, T., M. Tanaka, C. I. Brannan, N. A. Jenkins, N. G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969.
    • (1994) Cell , vol.76 , pp. 969
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3    Jenkins, N.A.4    Copeland, N.G.5    Suda, T.6    Nagata, S.7
  • 28
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata, S., and P. Golstein. 1995. The Fas death factor. Science 267:1449.
    • (1995) Science , vol.267 , pp. 1449
    • Nagata, S.1    Golstein, P.2
  • 30
    • 0029802697 scopus 로고    scopus 로고
    • Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity
    • Drappa, J., A. K. Vaishnaw, K. E. Sullivan, J. L. Chu, and K. B. Elkon. 1996. Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity. N. Engl. J. Med 335:1643.
    • (1996) N. Engl. J. Med , vol.335 , pp. 1643
    • Drappa, J.1    Vaishnaw, A.K.2    Sullivan, K.E.3    Chu, J.L.4    Elkon, K.B.5
  • 31
    • 0030952229 scopus 로고    scopus 로고
    • Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: A molecular and immu-nological analysis
    • Bettinardi, A., D. Brugnoni, E. Quiros-Roldan, A. Malagoli, S. La Grutta, A. Correra, and L. D. Notarangelo. 1997. Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: a molecular and immu-nological analysis. Blood 89:902.
    • (1997) Blood , vol.89 , pp. 902
    • Bettinardi, A.1    Brugnoni, D.2    Quiros-Roldan, E.3    Malagoli, A.4    La Grutta, S.5    Correra, A.6    Notarangelo, L.D.7
  • 32
    • 0029737324 scopus 로고    scopus 로고
    • Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease
    • Wu, J., J. Wilson, J. He, L. Xiang, P. H. Schur, and J. D. Mountz. 1996. Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease. J. Clin. Invest. 98:1107.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1107
    • Wu, J.1    Wilson, J.2    He, J.3    Xiang, L.4    Schur, P.H.5    Mountz, J.D.6
  • 37
    • 0029808372 scopus 로고    scopus 로고
    • The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
    • O'Connell, J., G. C. O'Sullivan, J. K. Collins, and F. Shanahan. 1996. The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand. J. Exp. Med. 184:1075.
    • (1996) J. Exp. Med. , vol.184 , pp. 1075
    • O'Connell, J.1    O'Sullivan, G.C.2    Collins, J.K.3    Shanahan, F.4
  • 38
    • 0029840585 scopus 로고    scopus 로고
    • Fas ligand and immune evasion
    • Nagata, S. 1996. Fas ligand and immune evasion. Nat. Med. 2:1306.
    • (1996) Nat. Med. , vol.2 , pp. 1306
    • Nagata, S.1
  • 39
    • 0031789409 scopus 로고    scopus 로고
    • Fas ligand expression in primary colon adenocarcinomas: Evidence that the Fas counterattack is a prevalent mechanism of immune evasion in human colon cancer
    • O'Connell, J., M. W. Bennett, G. C. O'Sullivan, D. Roche, J. Kelly, J. K. Collins, and F. Shanahan. 1998. Fas ligand expression in primary colon adenocarcinomas: evidence that the Fas counterattack is a prevalent mechanism of immune evasion in human colon cancer. J. Pathol. 186:240.
    • (1998) J. Pathol. , vol.186 , pp. 240
    • O'Connell, J.1    Bennett, M.W.2    O'Sullivan, G.C.3    Roche, D.4    Kelly, J.5    Collins, J.K.6    Shanahan, F.7
  • 40
    • 0031252369 scopus 로고    scopus 로고
    • Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system
    • Sabelko, K. A., K. A. Kelly, M. H. Nahm, A. H. Cross, and J. H. Russell. 1997. Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system. J. Immunol. 159:3096.
    • (1997) J. Immunol. , vol.159 , pp. 3096
    • Sabelko, K.A.1    Kelly, K.A.2    Nahm, M.H.3    Cross, A.H.4    Russell, J.H.5
  • 41
    • 0031253737 scopus 로고    scopus 로고
    • Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis
    • Waldner, H., R. A. Sobel, E. Howard, and V. K. Kuchroo. 1997. Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis. J. Immunol. 159:3100.
    • (1997) J. Immunol. , vol.159 , pp. 3100
    • Waldner, H.1    Sobel, R.A.2    Howard, E.3    Kuchroo, V.K.4
  • 42
    • 0031868315 scopus 로고    scopus 로고
    • Fas has a crucial role in the progression of experimental autoimmune encephalomyelitis
    • Okuda, Y., C. C. Bernard, H. Fujimura, T. Yanagihara, and S. Sakoda. 1998. Fas has a crucial role in the progression of experimental autoimmune encephalomyelitis. Mol. Immunol. 35:317.
    • (1998) Mol. Immunol. , vol.35 , pp. 317
    • Okuda, Y.1    Bernard, C.C.2    Fujimura, H.3    Yanagihara, T.4    Sakoda, S.5
  • 43
    • 0033583427 scopus 로고    scopus 로고
    • Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis
    • Sabelko-Downes, K. A., A. H. Cross, and J. H. Russell. 1999. Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis. J. Exp. Med. 189:1195.
    • (1999) J. Exp. Med. , vol.189 , pp. 1195
    • Sabelko-Downes, K.A.1    Cross, A.H.2    Russell, J.H.3
  • 46
    • 0031002790 scopus 로고    scopus 로고
    • Essential role of Fas ligand in the development of hepatitis
    • Kendo, T., T. Suda, H. Fukuyama, M. Adachi, and S. Nagata. 1997. Essential role of Fas ligand in the development of hepatitis. Nat. Med. 3:409.
    • (1997) Nat. Med. , vol.3 , pp. 409
    • Kendo, T.1    Suda, T.2    Fukuyama, H.3    Adachi, M.4    Nagata, S.5
  • 48
    • 0032532381 scopus 로고    scopus 로고
    • Involvement of the CD95 (APO-1/Fas) receptor and ligand system in Helicobacter pylori-induced gastric epithelial apoptosis
    • Rudi, J., D. Kuck, S. Strand, A. von Herbay, S. M. Mariani, P. H. Krammer, P. R. Galle, and W. Stremmel. 1998. Involvement of the CD95 (APO-1/Fas) receptor and ligand system in Helicobacter pylori-induced gastric epithelial apoptosis. J. Clin. Invest. 102:1506.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1506
    • Rudi, J.1    Kuck, D.2    Strand, S.3    Von Herbay, A.4    Mariani, S.M.5    Krammer, P.H.6    Galle, P.R.7    Stremmel, W.8
  • 49
    • 0028053599 scopus 로고
    • Human Fas ligand: Gene structure, chromosomal location and species specificity
    • Takahashi, T., M. Tanaka, J. Inazawa, T. Abe, T. Suda, and S. Nagata. 1994. Human Fas ligand: gene structure, chromosomal location and species specificity. Int. Immunol. 6:1567.
    • (1994) Int. Immunol. , vol.6 , pp. 1567
    • Takahashi, T.1    Tanaka, M.2    Inazawa, J.3    Abe, T.4    Suda, T.5    Nagata, S.6
  • 52
    • 0023601773 scopus 로고
    • Human necrosis factor potentiates human interlukin-1 mediated rat pancreatic β-cell cytotoxicity
    • Mandrup-Poulsen, T., K. Bendtzen, C.A., Dinarello, and J. Nerup. 1987. Human necrosis factor potentiates human interlukin-1 mediated rat pancreatic β-cell cytotoxicity. J. Immunol. 139:4077.
    • (1987) J. Immunol. , vol.139 , pp. 4077
    • Mandrup-Poulsen, T.1    Bendtzen, K.2    Dinarello, C.A.3    Nerup, J.4
  • 53
    • 0027934873 scopus 로고
    • TNF-α and IFn-γ potentiate the deleterious effects of IL-1β on mouse pancreatic islets mainly via generation of nitric oxide
    • Cetkovic-Cvrlje, M., and D. L. Eizirik. 1994. TNF-α and IFN-γ potentiate the deleterious effects of IL-1β on mouse pancreatic islets mainly via generation of nitric oxide. Cytokines 6:399.
    • (1994) Cytokines , vol.6 , pp. 399
    • Cetkovic-Cvrlje, M.1    Eizirik, D.L.2
  • 54
    • 0030997703 scopus 로고    scopus 로고
    • IFN-γ increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1
    • Heitmeier, M. R., A. L. Scarim, and J. A. Corbett. 1997. IFN-γ increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1. J. Biol. Chem. 272:13697.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13697
    • Heitmeier, M.R.1    Scarim, A.L.2    Corbett, J.A.3
  • 56
    • 0032523104 scopus 로고    scopus 로고
    • Cytokines and their roles in pancreatic islet β cell destruction and insulin-dependent diabetes mellitus
    • Rabinovitch, A., and W. L. Suarez-Pinzon. 1998. Cytokines and their roles in pancreatic islet β cell destruction and insulin-dependent diabetes mellitus. Biochem. Pharmacol. 55:1139.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1139
    • Rabinovitch, A.1    Suarez-Pinzon, W.L.2
  • 58
    • 0023784346 scopus 로고
    • INF-γ and tumor necrosis factor-α cytotoxicity to murine islets of Langerhans
    • Campbell, I. L., A. Iscaro, and L. C. Harrison. 1988. INF-γ and tumor necrosis factor-α cytotoxicity to murine islets of Langerhans. J. Immunol. 141:2325.
    • (1988) J. Immunol. , vol.141 , pp. 2325
    • Campbell, I.L.1    Iscaro, A.2    Harrison, L.C.3
  • 59
    • 0031033767 scopus 로고    scopus 로고
    • Prevention of autoimmune diabetes mellitus in NOD mice by transgenic expression of soluble tumor necrosis factor p55
    • Hunger, R. E., C. Carnaud, I. Garcia, P. Vassalli, and C. Mueller. 1997. Prevention of autoimmune diabetes mellitus in NOD mice by transgenic expression of soluble tumor necrosis factor p55. Eur. J. Immunol. 27:255.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 255
    • Hunger, R.E.1    Carnaud, C.2    Garcia, I.3    Vassalli, P.4    Mueller, C.5
  • 60
    • 0023841728 scopus 로고
    • Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-γ
    • Sarvetnick, N., D. Liggitt, S. L. Pitts, S. E. Hansen, and T. A. Stewart. 1988. Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-γ. Cell 52:773.
    • (1988) Cell , vol.52 , pp. 773
    • Sarvetnick, N.1    Liggitt, D.2    Pitts, S.L.3    Hansen, S.E.4    Stewart, T.A.5
  • 61
    • 0031051747 scopus 로고    scopus 로고
    • Interferon γ is essential for destruction of β cells and development of insulin-dependent diabetes mellitus
    • von Herrath, M. G., and M. B. A. Oldstone. 1996. Interferon γ is essential for destruction of β cells and development of insulin-dependent diabetes mellitus. J. Exp. Med. 185:531.
    • (1996) J. Exp. Med. , vol.185 , pp. 531
    • Von Herrath, M.G.1    Oldstone, M.B.A.2
  • 63
    • 0023001495 scopus 로고
    • Combined treatment with nicotinamide and desferrioxamine prevents islet allograft destruction in NOD mice
    • Nomikos, I. N., S. J. Prowse, P. Carotenuto, and K. J. Lafferty. 1986. Combined treatment with nicotinamide and desferrioxamine prevents islet allograft destruction in NOD mice. Diabetes 35:1302.
    • (1986) Diabetes , vol.35 , pp. 1302
    • Nomikos, I.N.1    Prowse, S.J.2    Carotenuto, P.3    Lafferty, K.J.4
  • 65
    • 0024463482 scopus 로고
    • Oxygen free radical scavengers protect rat islet cells from damage by cytokines
    • Sumoski, W., H. Baquerizo, and A. Rabinovitch. 1989. Oxygen free radical scavengers protect rat islet cells from damage by cytokines. Diabetologia 32:792.
    • (1989) Diabetologia , vol.32 , pp. 792
    • Sumoski, W.1    Baquerizo, H.2    Rabinovitch, A.3
  • 66
    • 0031968921 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms for the initiation and progression of β cell destruction resulting from the collaboration between macrophages and T cells
    • Yoon, J. W., H. S. Jun, and P. Santamaria. 1998. Cellular and molecular mechanisms for the initiation and progression of β cell destruction resulting from the collaboration between macrophages and T cells. Autoimmunity 27:109.
    • (1998) Autoimmunity , vol.27 , pp. 109
    • Yoon, J.W.1    Jun, H.S.2    Santamaria, P.3
  • 67
    • 0030890588 scopus 로고    scopus 로고
    • Cell death mediators in autoimmune diabetes: No shortage of suspects
    • Benoist, C., and D. Mathis. 1997. Cell death mediators in autoimmune diabetes: no shortage of suspects. Cell 89:1.
    • (1997) Cell , vol.89 , pp. 1
    • Benoist, C.1    Mathis, D.2
  • 69
    • 0033010882 scopus 로고    scopus 로고
    • Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases
    • Zhou, T., L. Song, P. Yang, Z. Wang, D. Lui, and R. S. Jope. 1999. Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases. Nat. Med. 5:42.
    • (1999) Nat. Med. , vol.5 , pp. 42
    • Zhou, T.1    Song, L.2    Yang, P.3    Wang, Z.4    Lui, D.5    Jope, R.S.6


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