Fas and Fas ligand expressed on cells of the immune system, not on the target tissue, control induction of experimental autoimmune uveitis

Journal of Immunology

Volumn 165, Issue 10, 2000, Pages 5480-5486

  Wahlsten, J L ^a   Gitchell, H L ^a   Chan, C C ^a   Wiggert, B ^a   Caspi, R R ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; FAS LIGAND;

ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNE DISEASE; BONE MARROW; CHIMERA; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UVEITIS;

EID: 0034670016     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.10.5480     Document Type: Article

References (34)

1. Identification of an immunodominant and highly immunopathogenic determinant in the retinal interphotoreceptor retinoid-binding protein (IRBP)
2. T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat
3. + T cell line and clone that induce experimental autoimmune uveoretinitis in B10.A mice
4. Retinal specific antigens and immunopathogenic processes they provoke
5. The Fas death factor
6. CD95(APO-1/Fas)-mediated apoptosis: Live and let die
7. Fas ligand-induced apoptosis as a mechanism of immune privilege
8. CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance
9. Apoptosis in patients with posterior uveitis
10. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
11. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
12. Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
13. Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system
14. Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis
15. Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis
16. Interphotoreceptor retinoid-binding protein (IRBP): Molecular biology and physiological role in the visual cycle of rhodopsin
17. Pathology of experimental autoimmune uveoretinitis in mice
18. Selective elimination of non-lpr lymphoid cells in mice undergoing lpr-mediated graft-vs-host disease
19. Association of lpr gene with graft-vs.-host disease-like syndrome
20. Massive up-regulation of the Fas ligand in lpr and gld mice: Implications for Fas regulation and the graft-versus-host disease-like wasting syndrome
21. Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders
22. Fas-FasL interactions: A common pathogenetic mechanism in organ-specific autoimmunity
23. Role of Fas/FasL interaction in physiology and pathology: The good and the bad
24. Effect of aqueous humor on apoptosis of inflammatory cell types
25. Regulation of the proinflammatory effects of Fas ligand (CD95L)
26. Chemotactic activity of soluble Fas ligand against phagocytes
27. Fas transduces activation signals in normal human T lymphocytes
28. Regulation of apoptosis and T cell activation by Fas-specific mAb
29. Development of inflammatory angiogenesis by local stimulation of Fas in vivo
30. Fas-mediated stimulation induces IL-8 secretion by rheumatoid arthritis synoviocytes independently of CPP32-mediated apoptosis
31. Histochemical localization of superoxide production in experimental autoimmune uveitis
32. Super-oxide generated by polymorphonuclear leukocytes and retinal lipid peroxidation in uveoretinitis
33. Agonist antibody and Fas ligand mediate different sensitivity to death in the signaling pathways of Fas and cytoplasmic mutants