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Volumn 22, Issue 8, 2001, Pages 420-426

Pharmacogenetic determinants of anti-cancer drug activity and toxicity

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; 7 HYDROXYSTAUROSPORINE; ALKYLATING AGENT; ANTHRACYCLINE ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CYCLOPHOSPHAMIDE; CYTARABINE; CYTOSINE; DAUNORUBICIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOCETAXEL; FLUOROURACIL; FOLIC ACID DERIVATIVE; GEMCITABINE; IRINOTECAN; MERCAPTOPURINE; METHOTREXATE; NAVELBINE; NUCLEOSIDE DERIVATIVE; PACLITAXEL; PREDNISOLONE; PYRIMIDINE DERIVATIVE; RIBONUCLEOTIDE REDUCTASE; TAXANE DERIVATIVE; TIOGUANINE; UNINDEXED DRUG; VINCA ALKALOID; VINCRISTINE;

EID: 0035425225     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(00)01742-9     Document Type: Review
Times cited : (55)

References (52)
  • 2
    • 0032896336 scopus 로고    scopus 로고
    • Review of the efficacy of individualized chemotherapy selected by in vitro drug sensitivity testing for patients with cancer
    • (1999) J. Clin. Oncol. , vol.17 , pp. 1625-1631
    • Cortazar, P.1    Johnson, B.E.2
  • 3
    • 0025870820 scopus 로고
    • Relation of cellular drug resistance to long-term clinical outcome in childhood acute lymphoblastic leukaemia
    • (1991) Lancet , vol.338 , pp. 399-403
    • Pieters, R.1
  • 4
    • 0034661614 scopus 로고    scopus 로고
    • Thymidylate synthase quantitation and in vitro chemosensitivity testing predicts responses and survival of patients with isolated nonresectable liver tumors receiving hepatic arterial infusion chemotherapy
    • (2000) Cancer , vol.89 , pp. 288-296
    • Link, K.H.1
  • 5
    • 0034109492 scopus 로고    scopus 로고
    • Correlation of drug response with the ATP tumor chemosensitivity assay in primary FIGO stage III ovarian cancer
    • (2000) Gynecol. Oncol. , vol.77 , pp. 258-263
    • Konecny, G.1
  • 7
    • 0034660560 scopus 로고    scopus 로고
    • Pharmacogenetics and the practice of medicine
    • (2000) Nature , vol.405 , pp. 857-865
    • Roses, A.D.1
  • 8
    • 0032809387 scopus 로고    scopus 로고
    • Gene expression profiling, genetic networks, and cellular states: An integrating concept for tumorigenesis and drug discovery
    • (1999) J. Mol. Med. , vol.77 , pp. 469-480
    • Huang, S.1
  • 12
    • 0033571118 scopus 로고    scopus 로고
    • In vivo gene expression profile analysis of human breast cancer progression
    • (1999) Cancer Res. , vol.59 , pp. 5656-5661
    • Sgroi, D.C.1
  • 14
    • 0033198464 scopus 로고    scopus 로고
    • Overexpression of ribonucleotide reductase as a mechanism of resistance to 2,2-difluorodeoxycytidine in the human KB cancer cell line
    • (1999) Cancer Res. , vol.59 , pp. 4204-4207
    • Goan, Y.G.1
  • 15
    • 18544412314 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer
    • (2000) J. Clin. Oncol. , vol.18 , pp. 927-941
    • Zujewski, J.1
  • 16
    • 0033757346 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents
    • (2000) Drugs , vol.60 , pp. 25-32
    • Ciardiello, F.1
  • 17
    • 0032701521 scopus 로고    scopus 로고
    • Disruption of p53 in human cancer cells alters the responses to therapeutic agents
    • (1999) J. Clin. Invest. , vol.104 , pp. 263-269
    • Bunz, F.1
  • 18
    • 0034729756 scopus 로고    scopus 로고
    • Spontaneous development of drug resistance: Mismatch repair and p53 defects in resistance to cisplatin in human tumor cells
    • (2000) Oncogene , vol.19 , pp. 3138-3145
    • Branch, P.1
  • 20
    • 0034660892 scopus 로고    scopus 로고
    • The Pezcoller lecture: Cancer cell cycles revisited
    • (2000) Cancer Res. , vol.60 , pp. 3689-3695
    • Sherr, C.J.1
  • 21
    • 0030609024 scopus 로고    scopus 로고
    • p16INK4 expression is associated with the increased sensitivity of human non-small cell lung cancer cells to DNA topoisomerase I inhibitors
    • (1997) Jpn. J. Cancer Res. , vol.88 , pp. 1009-1016
    • Fukuoka, K.1
  • 22
    • 0033568223 scopus 로고    scopus 로고
    • Cell cycle checkpoint abrogator UCN-01 inhibits DNA repair: Association with attenuation of the interaction of XPA and ERCC1 nucleotide excision repair proteins
    • (1999) Cancer Res. , vol.59 , pp. 4529-4534
    • Jiang, H.1    Yang, L.Y.2
  • 23
    • 0032852874 scopus 로고    scopus 로고
    • RB status as a determinant of response to UCN-01 in non-small cell lung carcinoma
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2596-2604
    • Mack, P.C.1
  • 24
    • 0032188839 scopus 로고    scopus 로고
    • Reversal of CPT-11 resistance of lung cancer cells by adenovirus-mediated gene transfer of the human carboxylesterase cDNA
    • (1998) Cancer Res. , vol.58 , pp. 4368-4374
    • Kojima, A.1
  • 25
    • 0034234872 scopus 로고    scopus 로고
    • dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: Association with survival and response to 5-fluorouracil in colorectal cancer
    • (2000) Cancer Res. , vol.60 , pp. 3493-3503
    • Ladner, R.D.1
  • 26
    • 0013357203 scopus 로고    scopus 로고
    • Pharmacogenetics of nucleoside metabolizing system in non small cell lung cancer: Implication for the chemotherapeutic efficacy of gemcitabine
    • (2001) Proc. Am. Assoc. Cancer Res. , vol.42 , pp. 1433
    • De Braud, F.1
  • 27
    • 0032946239 scopus 로고    scopus 로고
    • ATP-dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P
    • (1999) Mol. Pharmacol. , vol.55 , pp. 921-928
    • Chen, Z.S.1
  • 28
    • 0033568540 scopus 로고    scopus 로고
    • Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line
    • (1999) Cancer Res. , vol.59 , pp. 4559-4563
    • Maliepaard, M.1
  • 29
    • 0033897693 scopus 로고    scopus 로고
    • P-glycoprotein and multidrug resistance protein activities in relation to treatment outcome in acute myeloid leukemia
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3205-3214
    • Van der Kolk, D.M.1
  • 31
    • 0034669625 scopus 로고    scopus 로고
    • Expression of apoptosis-related proteins is an independent determinant of patient prognosis in advanced ovarian cancer
    • (2000) J. Clin. Oncol. , vol.18 , pp. 3775-3781
    • Baekelandt, M.1
  • 32
    • 0033066589 scopus 로고    scopus 로고
    • Apoptosis and Bcl-2 expression in relation to age, tumor characteristics and prognosis in breast cancer
    • (1999) Int. J. Biol. Markers , vol.14 , pp. 84-91
    • Holmqvist, P.1
  • 34
    • 0032129272 scopus 로고    scopus 로고
    • Bcl-xL is phosphorylated in malignant cells following microtubule disruption
    • (1998) Cancer Res. , vol.58 , pp. 3331-3338
    • Poruchynsky, M.S.1
  • 35
    • 0032212479 scopus 로고    scopus 로고
    • BAX expression is associated with enhanced intracellular accumulation of paclitaxel: A novel role for BAX during chemotherapy-induced cell death
    • (1998) Cancer Res. , vol.58 , pp. 4776-4781
    • Strobel, T.1
  • 36
    • 0031018983 scopus 로고    scopus 로고
    • Estrogen increases intracellular p26Bcl-2 to p21Bax ratios and inhibits taxol-induced apoptosis of human breast cancer MCF-7 cells
    • (1997) Breast Cancer Res. Treat. , vol.42 , pp. 73-81
    • Huang, Y.1
  • 37
    • 0030062205 scopus 로고    scopus 로고
    • Induction of the death-promoting gene bax-alpha sensitizes cultured breast-cancer cells to drug-induced apoptosis
    • (1996) Int. J. Cancer , vol.67 , pp. 138-141
    • Wagener, C.1
  • 38
    • 0033587157 scopus 로고    scopus 로고
    • Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein
    • (1999) Oncogene , vol.18 , pp. 3166-3172
    • Li, Y.1
  • 39
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor-γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 8806-8811
    • Elstner, E.1
  • 40
    • 0031687587 scopus 로고    scopus 로고
    • Bcl-2 overexpression is associated with resistance to paclitaxel, but not gemcitabine, in multiple myeloma cells
    • (1998) Int. J. Oncol. , vol.13 , pp. 839-848
    • Gazitt, Y.1
  • 41
    • 0034488052 scopus 로고    scopus 로고
    • Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: Identification of new mutations in the DPD gene
    • (2000) Clin. Cancer Res. , vol.6 , pp. 4705-4712
    • Van Kuilenburg, A.B.P.1
  • 42
    • 0032940053 scopus 로고    scopus 로고
    • Correlation between uracil and dihydrouracil plasma ratio, fluorouracil (5-FU) pharmacokinetic parameters, and tolerance in patients with advanced colorectal cancer: A potential interest for predicting 5-FU toxicity and determining optimal 5-FU dosage
    • (1999) J. Clin. Oncol. , vol.17 , pp. 1105-1112
    • Gamelin, E.1
  • 43
    • 0034034158 scopus 로고    scopus 로고
    • Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia
    • (2000) Leukemia , vol.14 , pp. 567-572
    • McLeod, H.L.1
  • 44
    • 0030934850 scopus 로고    scopus 로고
    • Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
    • (1997) Ann. Intern. Med. , vol.126 , pp. 608-614
    • Yates, C.R.1
  • 45
    • 0033998678 scopus 로고    scopus 로고
    • MTHFR gene polymorphism and severe toxicity during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil (CMF)
    • (2000) Ann. Oncol. , vol.11 , pp. 373-374
    • Toffoli, G.1
  • 47
    • 0034671387 scopus 로고    scopus 로고
    • Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis
    • (2000) Cancer Res. , vol.60 , pp. 6921-6926
    • Ando, Y.1
  • 48
    • 0033790607 scopus 로고    scopus 로고
    • Glutathione S-transferase genetic polymorphisms and individual sensitivity to the ototoxic effect of cisplatin
    • (2000) Anticancer Drugs , vol.11 , pp. 639-643
    • Peters, U.1
  • 51
    • 0031031373 scopus 로고    scopus 로고
    • Kinetics of arylamine N-acetyltransferase in tissues from human breast cancer
    • (1997) Cancer Lett. , vol.111 , pp. 39-50
    • Lee, J.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.