-
1
-
-
0029902591
-
Clinical, toxicological and pharmacological aspects of gemcitabine
-
Guchelaar, H. J., Richel, D. J., and van Knapen, A. Clinical, toxicological and pharmacological aspects of gemcitabine. Cancer Treat. Rev., 22: 15-31, 1983.
-
(1983)
Cancer Treat. Rev.
, vol.22
, pp. 15-31
-
-
Guchelaar, H.J.1
Richel, D.J.2
Van Knapen, A.3
-
2
-
-
0028799108
-
Gemcitabine: Metabolism, mechanisms of action, and self-potentiation
-
Plunkett, W., Huang, P., Xu, Y. Z., Heinemann, V., Grunewald, R., and Gandhi, V. Gemcitabine: metabolism, mechanisms of action, and self-potentiation. Semin. Oncol., 22 (Suppl. 11): 3-10, 1995.
-
(1995)
Semin. Oncol.
, vol.22
, Issue.SUPPL. 11
, pp. 3-10
-
-
Plunkett, W.1
Huang, P.2
Xu, Y.Z.3
Heinemann, V.4
Grunewald, R.5
Gandhi, V.6
-
3
-
-
0023783698
-
Comparison of the cellular pharmacokinetics and toxicity of 2,2-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine
-
Heinemann, V., Hertel, L. W., Grindey, G. B., and Plunkett, W. Comparison of the cellular pharmacokinetics and toxicity of 2,2-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine. Cancer Res., 48: 4024-4031, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 4024-4031
-
-
Heinemann, V.1
Hertel, L.W.2
Grindey, G.B.3
Plunkett, W.4
-
4
-
-
10344266073
-
Regulation of ribonucleotide reductase activity in mammalian cells
-
Cory, J. G., and Sato, A. Regulation of ribonucleotide reductase activity in mammalian cells. Mol. Cell. Biochem., 53: 257-266, 1983.
-
(1983)
Mol. Cell. Biochem.
, vol.53
, pp. 257-266
-
-
Cory, J.G.1
Sato, A.2
-
5
-
-
0022799261
-
Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase
-
Thelander, L., and Berg, P. Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase. Mol. Cell. Biol., 6: 3433-3422, 1986.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 3433-13422
-
-
Thelander, L.1
Berg, P.2
-
6
-
-
0031938457
-
Overexpression of transfected human ribonucleotide reductase M2 subunit in human cancer cells enhance their invasion potential
-
Zhou, B. S., Tsai, P., Ker, R., Tsai, J., Ho, R., Yu, J., Shih, J., and Yen, Y. Overexpression of transfected human ribonucleotide reductase M2 subunit in human cancer cells enhance their invasion potential. Clin. Exp. Metastasis, 16: 43-49, 1998.
-
(1998)
Clin. Exp. Metastasis
, vol.16
, pp. 43-49
-
-
Zhou, B.S.1
Tsai, P.2
Ker, R.3
Tsai, J.4
Ho, R.5
Yu, J.6
Shih, J.7
Yen, Y.8
-
7
-
-
0030450403
-
Ribonucleotide reductase R2 component is a novel malignancy determination that cooperates with activated oncogenes to determine transformation and malignant potential
-
Fan H., Villegas, C., and Wright, J. A. Ribonucleotide reductase R2 component is a novel malignancy determination that cooperates with activated oncogenes to determine transformation and malignant potential. Proc. Natl. Acad. Sci. USA, 93: 14036-14040, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14036-14040
-
-
Fan, H.1
Villegas, C.2
Wright, J.A.3
-
8
-
-
0025325071
-
Evaluation of the antitumor activity of gemcitabine (2,2-difluoro-2-deoxycytidine)
-
Hertel, L. W., Boder, G. B., Kroin, J. S., Rinzel, S. M., Poore, G. A., Todd, G. C., and Grindey, G. B. Evaluation of the antitumor activity of gemcitabine (2,2-difluoro-2-deoxycytidine). Cancer Res., 50: 4417-4422, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 4417-4422
-
-
Hertel, L.W.1
Boder, G.B.2
Kroin, J.S.3
Rinzel, S.M.4
Poore, G.A.5
Todd, G.C.6
Grindey, G.B.7
-
9
-
-
0025977171
-
Preclinical in vivo activity of 2,2-difluorodeoxycytidine (gemcitabine) against human head and neck cancer
-
Braakhuis, B. J. M., Van Dongen, G. A. M. S., Vermorken, J. B., and Snow, G. B. Preclinical in vivo activity of 2,2-difluorodeoxycytidine (gemcitabine) against human head and neck cancer. Cancer Res., 51: 211-214, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 211-214
-
-
Braakhuis, B.J.M.1
Van Dongen, G.A.M.S.2
Vermorken, J.B.3
Snow, G.B.4
-
10
-
-
0028067217
-
Development and molecular characterization of a 2, 2-difluorodeoxycytidine resistant variant of the human ovarian carcinoma cell line A2780
-
Ruiz van Haperen V. W. T., Veerman, G., Eriksson, S., Boven, E., Stegmann, A. P. A., Hermsen, M., Vermorken, J. B., Pinedo, H. M., and Peters, G. J. Development and molecular characterization of a 2, 2-difluorodeoxycytidine resistant variant of the human ovarian carcinoma cell line A2780. Cancer Res., 54: 4138-4143, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 4138-4143
-
-
Ruiz Van Haperen, V.W.T.1
Veerman, G.2
Eriksson, S.3
Boven, E.4
Stegmann, A.P.A.5
Hermsen, M.6
Vermorken, J.B.7
Pinedo, H.M.8
Peters, G.J.9
-
11
-
-
0021719254
-
Isolation and characterization of a deoxycytidine kinase-deficient human promyelocytic leukemic cell line highly resistant to 1-β-D-arabinofuranosylcytosine
-
Bhalla, K., Nayak, R., and Grant, S. Isolation and characterization of a deoxycytidine kinase-deficient human promyelocytic leukemic cell line highly resistant to 1-β-D-arabinofuranosylcytosine. Cancer Res., 44: 5029-5037, 1984.
-
(1984)
Cancer Res.
, vol.44
, pp. 5029-5037
-
-
Bhalla, K.1
Nayak, R.2
Grant, S.3
-
12
-
-
0020072941
-
1-β-D-arabinofuranosylcytosine influx and nucleoside transport sites in acute leukemia
-
Wiley, J. S., Jones, S. P., Sawyer, W. H., and Paterson, A. R. P. 1-β-D-arabinofuranosylcytosine influx and nucleoside transport sites in acute leukemia. J. Clin. Invest., 69: 479-489, 1982.
-
(1982)
J. Clin. Invest.
, vol.69
, pp. 479-489
-
-
Wiley, J.S.1
Jones, S.P.2
Sawyer, W.H.3
Paterson, A.R.P.4
-
13
-
-
0024397460
-
Augmentation of 1-β-D-arabinofuranosylcytosine cytotoxicity in human tumor cells by inhibiting drug efflux
-
Chan, T. C. K., Augmentation of 1-β-D-arabinofuranosylcytosine cytotoxicity in human tumor cells by inhibiting drug efflux. Cancer Res., 49: 2656-2660, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 2656-2660
-
-
Chan, T.C.K.1
-
14
-
-
0028107848
-
Characterization of a hydroxyurea-resistant human KB cell line with supersensitivity to 6-thioguanine
-
Yen, Y., Grill, S. P., Dutschman, G. E., Chang, C. N., Zhou, B. S., and Cheng, Y. C. Characterization of a hydroxyurea-resistant human KB cell line with supersensitivity to 6-thioguanine. Cancer Res., 54: 3686-3691, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3686-3691
-
-
Yen, Y.1
Grill, S.P.2
Dutschman, G.E.3
Chang, C.N.4
Zhou, B.S.5
Cheng, Y.C.6
-
15
-
-
0028928261
-
Overexpression of ribonucleotide reductase in transfected human KB cells increases their resistance to hydroxyurea: M2 but not M1 is sufficient to increase resistance to hydroxyurea in transfected cells
-
Zhou, B. S., Hsu, N. Y., Pan, B. C., Doroshow, J. H., and Yen, Y. Overexpression of ribonucleotide reductase in transfected human KB cells increases their resistance to hydroxyurea: M2 but not M1 is sufficient to increase resistance to hydroxyurea in transfected cells. Cancer Res., 55: 1328-1333, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 1328-1333
-
-
Zhou, B.S.1
Hsu, N.Y.2
Pan, B.C.3
Doroshow, J.H.4
Yen, Y.5
-
16
-
-
0032524942
-
Determination of deoxyribonucleoside triphosphate pool size in ribonucleotide reductase cDNA transfected human KB cells
-
Zhou, B. S., Ker, R., Ho, R., Yu J., Zhao, Y. R., Shih, J., and Yen, Y. Determination of deoxyribonucleoside triphosphate pool size in ribonucleotide reductase cDNA transfected human KB cells. Biochem. Pharmacol., 55: 1657-1665, 1998.
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 1657-1665
-
-
Zhou, B.S.1
Ker, R.2
Ho, R.3
Yu, J.4
Zhao, Y.R.5
Shih, J.6
Yen, Y.7
-
17
-
-
0014759788
-
A rapid assay for CDP reductase activity in mammalian cell extracts
-
Steeper, J. P., and Stuart, C. D. A rapid assay for CDP reductase activity in mammalian cell extracts. Anal. Biochem., 34: 123-130, 1970.
-
(1970)
Anal. Biochem.
, vol.34
, pp. 123-130
-
-
Steeper, J.P.1
Stuart, C.D.2
-
18
-
-
0014663461
-
Rapid determination of nucleoside kinase and nucleotidase activities with tritium-labeled substrates
-
Ivies, D. H., Durhan, J. P., and Tucker, V. S. Rapid determination of nucleoside kinase and nucleotidase activities with tritium-labeled substrates. Anal. Biochem., 28: 192-205, 1968.
-
(1968)
Anal. Biochem.
, vol.28
, pp. 192-205
-
-
Ivies, D.H.1
Durhan, J.P.2
Tucker, V.S.3
-
19
-
-
0017184389
-
A rapid and sensitive method for the qualification of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. A. A rapid and sensitive method for the qualification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72: 248-254, 1976.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.A.1
-
20
-
-
0031837962
-
Induction of in vivo resistance against gemcitabine
-
Ruiz van Haperen, V. M. T., Veerman, G., van Moorsel, C. T. A., and Peters, G. J. Induction of in vivo resistance against gemcitabine. Adv. Exp. Med. Biol., 431: 637-640, 1998.
-
(1998)
Adv. Exp. Med. Biol.
, vol.431
, pp. 637-640
-
-
Ruiz Van Haperen, V.M.T.1
Veerman, G.2
Van Moorsel, C.T.A.3
Peters, G.J.4
|