-
1
-
-
0031603399
-
New antimetabolites in cancer chemotherapy and their clinical impact
-
(1998)
Br. J. Cancer
, vol.78
, Issue.SUPPL. 3
, pp. 1-7
-
-
Kaye, S.B.1
-
2
-
-
0030870485
-
Gemcitabine. A review of its pharmacology and clinical potential in non-small cell lung cancer and pancreatic cancer
-
(1997)
Drugs
, vol.54
, pp. 447-472
-
-
Noble, S.1
Goa, K.L.2
-
6
-
-
0029053894
-
Metabolism and actions of 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine in human lymphoblastoid cells
-
(1995)
Cancer Res.
, vol.55
, pp. 2847-2852
-
-
Xie, C.1
Plunkett, W.2
-
7
-
-
0032697561
-
The ribonucleoside diphosphate reductase inhibitor (E)-2′-deoxy-(fluoromethylene)cytidine as a cytotoxic radiosensitizer in vitro
-
(1999)
Cancer Res.
, vol.59
, pp. 5219-5226
-
-
Coucke, P.A.1
Decosterd, L.A.2
Li, Y.X.3
Cottin, E.4
Chen, X.5
Sun, L.Q.6
Stern, S.7
Paschoud, N.8
Denekamp, J.9
-
11
-
-
0025872936
-
1-β-D-arabinofuranosylcytosine in the treatment of acute myeloid leukemia: The role and place of high-dose regimens
-
(1991)
Ann. Hematol.
, vol.62
, pp. 119-128
-
-
Hiddemann, W.1
-
14
-
-
0019213534
-
Prediction of response to chemotherapy in acute myelocytic leukemia
-
(1980)
Blood
, vol.56
, pp. 361-367
-
-
Preisler, H.D.1
-
17
-
-
0025876872
-
Cellular and pharmacologic aspects of drug resistance in acute myeloid leukemia
-
(1991)
Curr. Opin. Oncol.
, vol.3
, pp. 21-29
-
-
Ross, D.D.1
-
26
-
-
0021832010
-
S1-phase cells of the leukemic cell cycle sensitive to 1-β-D-arabinofuranosylcytosine at a high-dose level
-
(1985)
Cancer Res.
, vol.45
, pp. 3113-3117
-
-
Smets, L.A.1
Homan-Blok, J.2
-
34
-
-
0034616329
-
Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10342-10348
-
-
Zhou, B.B.1
Chaturvedi, P.2
Spring, K.3
Scott, S.P.4
Johanson, R.A.5
Mishra, R.6
Mattern, M.R.7
Winkler, J.D.8
Khanna, K.K.9
-
37
-
-
0033199892
-
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
-
(1999)
Cancer Res.
, vol.59
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Busby, E.C.2
Tibbetts, R.S.3
Roos, P.4
Taya, Y.5
Karnitz, L.M.6
Abraham, R.T.7
-
39
-
-
0032729120
-
Comparison of the efficacy of 7-hydroxystaurosporine (UCN-01) and other staurosporine analogs to abrogate cisplatin-induced cell cycle arrest in human breast cancer cell lines
-
(1999)
Biochem. Pharmacol.
, vol.58
, pp. 1713-1721
-
-
Lee, S.I.1
Brown, M.K.2
Eastman, A.3
-
41
-
-
0033104319
-
Altered pharmacokinetics of a novel anticancer drug, UCN-01, caused by specific high affinity binding to α-1-acid glycoprutein in humans
-
(1999)
Cancer Res.
, vol.59
, pp. 1054-1060
-
-
Fuse, E.1
Tanii, H.2
Takai, K.3
Asanome, K.4
Kurata, N.5
Kobayashi, H.6
Kuwabara, T.7
Kobayashi, S.8
Sugiyama, Y.9
-
42
-
-
0031672099
-
Clinical pharmacology of UCN-01: Initial observations and comparison to preclinical models
-
(1998)
Cancer Chemother. Pharmacol.
, vol.42
, Issue.SUPPL.
-
-
Sausville, E.A.1
Lush, R.D.2
Headiee, D.3
Smith, A.C.4
Figg, W.D.5
Arbuck, S.G.6
Senderuwicz, A.M.7
Fuse, E.8
Tanii, H.9
Kuwabara, T.10
Kobayashi, S.11
-
48
-
-
0030811613
-
7-Hydruxystaurosporine (UCN-01) causes redistribution of proliferating cell nuclear antigen and abrogates cisplatin-induced S-phase arrest in Chinese hamster ovary cells
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 779-788
-
-
Bunch, R.T.1
Eastman, A.2
-
49
-
-
0033953099
-
UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G(2) checkpoint abrogation
-
(2000)
Int. J. Cancer
, vol.85
, pp. 703-709
-
-
Sugiyama, K.1
Shimizu, M.2
Akiyama, T.3
Tamaoki, T.4
Yamaguchi, K.5
Takahashi, R.6
Eastman, A.7
Akinaga, S.8
-
54
-
-
0025224518
-
Direct relationship between remission duration in acute myeloid leukemia and cell cycle kinetics: A leukemia intergroup study
-
(1990)
Blood
, vol.76
, pp. 2191-2197
-
-
Raza, A.1
Preisler, H.D.2
Day, R.3
Yasin, Z.4
White, M.5
Lykins, J.6
Kukla, C.7
Barcos, M.8
Bennett, J.9
Browman, G.10
-
57
-
-
0032766844
-
Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6183-6194
-
-
Blomberg, I.1
Hoffmann, I.2
-
63
-
-
0033566082
-
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
-
(1999)
Oncogene
, vol.18
, pp. 4047-4054
-
-
Chaturvedi, P.1
Eng, W.K.2
Zhu, Y.3
Mattern, M.R.4
Mishra, R.5
Hurle, M.R.6
Zhang, X.7
Annan, R.S.8
Lu, Q.9
Faucette, L.F.10
Scott, G.F.11
Li, X.12
Cart, S.A.13
Johnson, R.K.14
Winker, J.D.15
Zhou, B.B.16
-
72
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.I.2
Chan, T.O.3
Datta, K.4
Kazlauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
74
-
-
0005994703
-
Inhibition of the PI 3-kinase/Akt-BAD survival pathway by UCN-01 is associated with abrogation of gemcitabine-induced S phase arrest and induction of apoptosis
-
(2000)
Proc. Am. Assoc. Cancer Res.
, vol.41
, pp. 313
-
-
Shi, Z.1
Plunkett, W.2
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