Structural analysis of two HLA-DR-presented autoantigenic epitopes: Crucial role of peripheral but not central peptide residues for T-cell receptor recognition

Molecular Immunology

Volumn 37, Issue 14, 2000, Pages 813-825

  De Oliveira, Daniel B ^a   Harfouch Hammoudl, Elham ^b   Otto, Heike ^c   Papandreou, Nicolaos A ^d   Stern, Lawrence J ^a   Cohen, Hélène ^b   Boehm, Bernhard O ^e   Bach, Jean Marie ^b   Caillat Zucman, Sophie ^b   Walk, Tilmann ^c   Jung, Günther ^c   Eliopoulos, Elias ^d   Papadopoulos, George K ^f   Van Endert, Peter M ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b INSERM   (France)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d AGRICULTURAL UNIVERSITY OF ATHENS   (Greece)

^e UNIVERSITY HOSPITAL ULM   (Germany)

^f Faculty of Agricultural Technology   (Greece)

Author keywords

Antigen presentation; Autoimmunity; Major histocompatibility complex; Peptides epitopes; T cell receptors

Indexed keywords

EPITOPE; HLA DR ANTIGEN; PEPTIDE; T LYMPHOCYTE RECEPTOR;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; CELLULAR DISTRIBUTION; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; EPITOPE MAPPING; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STRUCTURE ANALYSIS; T LYMPHOCYTE ACTIVATION;

EID: 0035106138     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(00)00109-7     Document Type: Article

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