T-cell receptor peptide-MHC interactions: Biological lessons from structural studies

Current Opinion in Biotechnology

Volumn 9, Issue 4, 1998, Pages 338-343

  Garcia, K Christopher ^a   Teyton, Luc ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE RECEPTOR;

CRYSTAL STRUCTURE; HUMAN; MODEL; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE RECEPTOR GENE;

EID: 0032146406     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0958-1669(98)80004-9     Document Type: Article

References (37)

1. Davis MM, Bjorkman PJ. T-cell antigen receptor genes and T-cell recognition. Nature. 334:1988;395-402.
2. Fields BA, Ysern X, Poljak RJ, Shao X, Ward ES, Mariuzza RA. Crystallization and preliminary X-ray diffraction study of a bacterially produced T-cell antigen receptor Vα domain. J Mol Biol. 239:1994;339-341.
3. Boulot G, Bentley GA, Karjalainen K, Mariuzza RA. Crystallization and preliminary X-ray diffraction analysis of the β-chain of a T-cell antigen receptor. J Mol Biol. 235:1994;795-797.
4. Garboczi DN, Utz U, Ghosh P, Seth A, Kim J, VanTienhoven EA, Biddison WE, Wiley DC. Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2. J Immunol. 157:1996;5403-5410.
5. Garcia KC, Tallquist MD, Pease LR, Brunmark A, Scott CA, Degano M, Stura EA, Peterson PA, Wilson IA, Teyton L. αβ T-cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization. Proc Natl Acad Sci USA. 94:1997;13838-13843.
6. Liu J, Tse AGD, Chang HC, Liu J, Wang J, Hussey RE, Chishti Y, Rheinhold B, Spoerl R, Nathenson SG, et al. Crystallization of a deglycosylated T cell receptor (TCR) complexed with an anti-TCR Fab fragment. J Biol Chem. 271:1996;33639-33646.
7. Gregoire C, Malissen B, Mazza G. Characterization of T cell receptor single-chain Fv fragments secreted by myeloma cells. Eur J Immunol. 26:1996;2410-2416.
8. Lin AY, Devaux B, Green A, Sagerstrom C, Elliott JF, Davis MM. Expression of T cell antigen receptor heterodimers in a lipid-linked form. Science. 249:1990;677-679.
9. Corr MA, Slanetz A, Boyd L, Jelonek M, Khiko S, Al-Ramidi B, Kim Y, Maher S, Bothwell A, Margulies D. T cell receptor-MHC class I peptide interactions: affinity, kinetics and specificity. Science. 265:1994;946-948.
10. Engel I, Ottenhoff TH, Klausner RD. High-efficiency expression and solubilization of functional T cell antigen receptor heterodimers. Science. 256:1992;1318-1321.
11. Chung S, Wucherpfennig KW, Friedman SM, Hafler DA, Strominger JL. Functional three-domain single-chain T-cell receptors. Proc Natl Acad Sci USA. 91:1994;12654-12658.
12. Weber S, Traunecker A, Oliveri F, Gerhard W, Karjalainen K. Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptor. Nature. 356:1992;793-796.
13. Hilyard KL, Reyburn H, Chung S, Bell JI, Strominger JL. Binding of soluble natural ligands to a soluble human T-cell receptor fragment produced in Escherichia coli. Proc Natl Acad Sci USA. 91:1994;9057-9061.
14. Plaksin D, Polakova K, McPhie P, Margulies DH. A three-domain T cell receptor is biologically active and specifically stains cell surface MHC/peptide complexes. J Immunol. 158:1997;2218-2227.
15. Schlueter CJ, Schodin BA, Tetin SY, Kranz DM. Specificity and binding properties of a single-chain T cell receptor. J Mol Biol. 256:1996;859-869.
16. Chothia CD, Boswell DR, Lesk AM. The outline structure of the T-cell αβ receptor. EMBO J. 7:1988;3745-3755.
17. Novotny J, Tonegawa S, Saito H, Kranz D, Eisen H. Secondary, tertiary and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains. Proc Natl Acad Sci USA. 83:1986;742-746.
18. Fields BA, Ober B, Malchiodi EL, Lebedeva MI, Braden BC, Ysern X, Kim JK, Shao Z, Ward ES, Mariuzza RA. Crystal structure of the Vα domain of a T cell antigen receptor. Science. 270:1995;1821-1824.
19. Bentley G, Boulot G, Karjalainen K, Mariuzza RA. Crystal structure of the β chain of a T cell antigen receptor. Science. 267:1995;1984-1987.
20. Garcia KC, Degano M, Stanfield RL, Brunmark A, Jackson MR, Peterson PA, Teyton L, Wilson IA. An αβ T cell receptor structure at 2.5 Å and its orientation in the TCR-MHC complex. Science. 274:1996;209-219.
21. Garboczi DN, Ghosh P, Utz U, Fan QR, Biddison WE, Wiley DC. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature. 384:1996;134-141.
22. Housset D, Mazza G, Gregoire C, Piras C, Malissen B, Fontecilla Camps JC. The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain. EMBO J. 16:1997;4205-4216.
23. Wang J, Lim K, Smolyar A, Teng M, Liu J, Tse AG, Liu J, Hussey RE, Chishti Y, Thomson CT, et al. Atomic structure of an αβ T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. EMBO J. 17:1998;10-26.
24. Garcia KC, Degano M, Pease LR, Huang M, Peterson PA, Teyton L, Wilson AI. Structural basis of plasticity in T cell receptor recognition of a self peptide - MHC antigen. Science. 279:1998;1166-1172.
25. Wilson IA, Garcia KC. T-cell receptor structure and TCR complexes. Curr Opin Struct Biol. 7:1997;839-848.
26. Fields BA, Mariuzza RA. Structure and function of the T-cell receptor: insights from X-ray crystallography. Immunol Today. 17:1996;330-336.
27. Stanfield RL, Wilson IA. Protein-peptide interactions. Curr Opin Struct Biol. 5:1995;103-113.
28. Jorgensen JL, Esser U, de St Groth BF, Reay PA, Davis MM. Mapping T-cell receptor - peptide contacts by variant peptide immunization of single-chain transgenics. Nature. 355:1992;224-230.
29. Sant'Angelo D, Waterbury G, Preston-Hurlburt P, Yoon R, Medzhitov R, Hong S, Janeway C. The specificity and orientation of a TCR to its peptide - MHC class II ligands. Immunity. 4:1996;367-376.
30. b molecule. Immunity. 3:1995;573-582.
31. Sim BC, Zerva L, Greene MI, Gascoigne MR. Control of MHC restriction by TCR Valpha CDR1 and CDR2. Science. 273:1996;963-966.
32. Nikolic-Zugic J, Bevan MJ. Role of self-peptides in positively selecting the T-cell repertoire. Nature. 344:1990;65-67.
33. Tallquist MD, Weaver AJ, Pease LR. Degenerative recognition of alloantigenic peptides on a positively-selecing class I molecule. J Immunol. 1998;. in press.
34. Exley M, Wileman T, Mueller B, Terhorst C. Evidence for multivalent structure of T-cell antigen receptor complex. Mol Immunol. 32:1995;829-839.
35. Weiss A. T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinases. Cell. 73:1993;209-212.
36. Reich Z, Boniface JJ, Lyons DS, Borochov N, Wachtel EJ, Davis MM. Ligand-specific oligomerization of T-cell receptor molecules. Nature. 387:1997;617-620.
37. Schodin BA, Tsomides TJ, Kranz DM. Correlation between the number of T cell receptors required to T cell activation and TCR-ligand affinity. Immunity. 5:1996;137-146.