메뉴 건너뛰기




Volumn 10, Issue 4, 1997, Pages 375-386

High affinity presentation of an autoantigenic peptide in type I diabetes by an HLA class II, protein encoded in a haplotype protecting from disease

Author keywords

Glutamic acid decarboxylase; HLA class II presentation; Insulin dependent diabetes mellitus; T cell epitopes

Indexed keywords

AUTOANTIGEN; HLA ANTIGEN CLASS 2;

EID: 0031214615     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.1997.0143     Document Type: Article
Times cited : (58)

References (45)
  • 2
    • 0024232747 scopus 로고
    • Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: Transfer of protection by splenic T cells
    • Boitard C., Bendelac A., Richard M.F., Carnaud C., Bach J.F. Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: transfer of protection by splenic T cells. Proc. Natl. Acad. Sci. USA. 85:1988;9719-9723.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 9719-9723
    • Boitard, C.1    Bendelac, A.2    Richard, M.F.3    Carnaud, C.4    Bach, J.F.5
  • 3
    • 0027468997 scopus 로고
    • Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice
    • Christianson S.W., Shultz L.D., Leiter E.H. Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Diabetes. 42:1993;44-55.
    • (1993) Diabetes , vol.42 , pp. 44-55
    • Christianson, S.W.1    Shultz, L.D.2    Leiter, E.H.3
  • 4
    • 0025817428 scopus 로고
    • MHC class-II molecules and autoimmunity
    • Nepom G.T., Erlich H. MHC class-II molecules and autoimmunity. Annu. Rev. Immunol. 9:1991;493-525.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 493-525
    • Nepom, G.T.1    Erlich, H.2
  • 5
    • 0027238178 scopus 로고
    • Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type I (insulin-dependent) diabetes mellitus
    • Thorsby E., Ronningen K.S. Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type I (insulin-dependent) diabetes mellitus. Diabetologia. 36:1993;371-377.
    • (1993) Diabetologia , vol.36 , pp. 371-377
    • Thorsby, E.1    Ronningen, K.S.2
  • 7
    • 0020568890 scopus 로고
    • The genetic susceptibility of type-1 (insulin dependent) diabetes: Analysis of the HLA-DR association
    • Wolf E., Spencer K.M., Cudworth A.G. The genetic susceptibility of type-1 (insulin dependent) diabetes: analysis of the HLA-DR association. Diabetologia. 24:1983;224-230.
    • (1983) Diabetologia , vol.24 , pp. 224-230
    • Wolf, E.1    Spencer, K.M.2    Cudworth, A.G.3
  • 8
    • 0021707829 scopus 로고
    • HLA-DR antigens and susceptibility to insulin-dependent diabetes mellitus
    • Thomson G. HLA-DR antigens and susceptibility to insulin-dependent diabetes mellitus. Am. J. Hum. Genet. 36:1984;1309-1317.
    • (1984) Am. J. Hum. Genet. , vol.36 , pp. 1309-1317
    • Thomson, G.1
  • 10
    • 0025729141 scopus 로고
    • Distribution of HLA-DRB1, -DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus
    • Ronningen K.S., Spurkland A., Iwe T., Vartdal F., Thorsby E. Distribution of HLA-DRB1, -DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus. Tissue Antigens. 37:1991;105-111.
    • (1991) Tissue Antigens , vol.37 , pp. 105-111
    • Ronningen, K.S.1    Spurkland, A.2    Iwe, T.3    Vartdal, F.4    Thorsby, E.5
  • 11
    • 0027408095 scopus 로고
    • Both DQA1 and DQB1 genes are implicated in HLA-associated protection from type 1 (insulin-dependent) diabetes mellitus in a British Caucasian population
    • Cavan D.A., Jacobs K.H., Penny M.A., Kelly M.A., Mijovic C., Jenkins D., Fletcher J.A., Barnett A.H. Both DQA1 and DQB1 genes are implicated in HLA-associated protection from type 1 (insulin-dependent) diabetes mellitus in a British Caucasian population. Diabetologia. 36:1993;252-257.
    • (1993) Diabetologia , vol.36 , pp. 252-257
    • Cavan, D.A.1    Jacobs, K.H.2    Penny, M.A.3    Kelly, M.A.4    Mijovic, C.5    Jenkins, D.6    Fletcher, J.A.7    Barnett, A.H.8
  • 12
    • 0028989040 scopus 로고
    • HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM
    • Pugliese A., Gianani R., Moromisato R., Awdeh Z.L., Alper C.A., Erlich H.A., Jackson R.A., Eisenbarth G.S. HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM. Diabetes. 44:1995;608-613.
    • (1995) Diabetes , vol.44 , pp. 608-613
    • Pugliese, A.1    Gianani, R.2    Moromisato, R.3    Awdeh, Z.L.4    Alper, C.A.5    Erlich, H.A.6    Jackson, R.A.7    Eisenbarth, G.S.8
  • 16
    • 0025358777 scopus 로고
    • Autoimmune diseases: The failure of self tolerance
    • Sinha A.A., Lopez M.T., McDevitt H.O. Autoimmune diseases: the failure of self tolerance. Science. 248:1990;1380-1388.
    • (1990) Science , vol.248 , pp. 1380-1388
    • Sinha, A.A.1    Lopez, M.T.2    McDevitt, H.O.3
  • 17
    • 0029010646 scopus 로고
    • In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleen of diabetic NOD mice
    • Healey D., Ozegbe P., Arden S., Chandler P., Hutton J., Cooke A. In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleen of diabetic NOD mice. J. Clin. Invest. 95:1995;2979-2985.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2979-2985
    • Healey, D.1    Ozegbe, P.2    Arden, S.3    Chandler, P.4    Hutton, J.5    Cooke, A.6
  • 18
    • 0028890866 scopus 로고
    • Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases
    • Liblau R.S., Singer S.M., McDevitt H.O. Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol. Today. 16:1995;34-38.
    • (1995) Immunol. Today , vol.16 , pp. 34-38
    • Liblau, R.S.1    Singer, S.M.2    McDevitt, H.O.3
  • 19
    • 0029030964 scopus 로고
    • T helper cell subsets in insulin-dependent diabetes
    • Katz J.D., Benoist C., Mathis D. T helper cell subsets in insulin-dependent diabetes. Science. 268:1995;1185-1188.
    • (1995) Science , vol.268 , pp. 1185-1188
    • Katz, J.D.1    Benoist, C.2    Mathis, D.3
  • 20
    • 0025131118 scopus 로고
    • A unified hypothesis for the complex genetics of HLA associations with IDDM
    • Nepom G.T. A unified hypothesis for the complex genetics of HLA associations with IDDM. Diabetes. 39:1990;1153-1157.
    • (1990) Diabetes , vol.39 , pp. 1153-1157
    • Nepom, G.T.1
  • 21
    • 0026500805 scopus 로고
    • HLA and insulin-dependent diabetes. A protective perspective
    • Sheehy M.J. HLA and insulin-dependent diabetes. A protective perspective. Diabetes. 41:1992;123-129.
    • (1992) Diabetes , vol.41 , pp. 123-129
    • Sheehy, M.J.1
  • 25
    • 0027908753 scopus 로고
    • Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
    • Tisch R., Yand X.-D., Singer S.M., Liblau R.S., Fugger L., McDevitt H.O. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature. 366:1993;72-75.
    • (1993) Nature , vol.366 , pp. 72-75
    • Tisch, R.1    Yand, X.-D.2    Singer, S.M.3    Liblau, R.S.4    Fugger, L.5    McDevitt, H.O.6
  • 28
    • 0027176158 scopus 로고
    • Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes
    • Harrison L.C., Honeyman M.C., DeAizpurua H.J., Schmidli R.S., Colman P.G., Tait B.D., Cram D.S. Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes. Lancet. 341:1993;1365-1369.
    • (1993) Lancet , vol.341 , pp. 1365-1369
    • Harrison, L.C.1    Honeyman, M.C.2    Deaizpurua, H.J.3    Schmidli, R.S.4    Colman, P.G.5    Tait, B.D.6    Cram, D.S.7
  • 29
    • 0029550748 scopus 로고
    • T cell proliferative responses to glutamic acid decarboxylase-65 in IDDM are negatively associated with HLA DR3/4
    • Worsaae A., Hejnaes K., Moody A., Ludvigsson J., Pociot F., Lorenzen T., Dyrberg T. T cell proliferative responses to glutamic acid decarboxylase-65 in IDDM are negatively associated with HLA DR3/4. Autoimmunity. 22:1995;183-189.
    • (1995) Autoimmunity , vol.22 , pp. 183-189
    • Worsaae, A.1    Hejnaes, K.2    Moody, A.3    Ludvigsson, J.4    Pociot, F.5    Lorenzen, T.6    Dyrberg, T.7
  • 30
    • 0028333066 scopus 로고
    • Immunodominant epitopes of glutamic acid decarboxylase 65 and 67 in insulin-dependent diabetes mellitus
    • Lohmann T., Leslie R.D.G., Hawa M., Geysen M., Rodda S., Londei M. Immunodominant epitopes of glutamic acid decarboxylase 65 and 67 in insulin-dependent diabetes mellitus. Lancet. 343:1994;1607-1608.
    • (1994) Lancet , vol.343 , pp. 1607-1608
    • Lohmann, T.1    Leslie, R.D.G.2    Hawa, M.3    Geysen, M.4    Rodda, S.5    Londei, M.6
  • 31
    • 0028007192 scopus 로고
    • Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes
    • Atkinson M.A., Bowman M.A., Campbell L., Darrow B.L., Kaufman D.L., Mclaren N.K. Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes. J. Clin. Invest. 94:1994;2125-2129.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2125-2129
    • Atkinson, M.A.1    Bowman, M.A.2    Campbell, L.3    Darrow, B.L.4    Kaufman, D.L.5    McLaren, N.K.6
  • 33
    • 0023879477 scopus 로고
    • Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase
    • Chang Y.C., Gottlieb D.I. Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase. J. Neurosci. 8:1988;2123-2130.
    • (1988) J. Neurosci. , vol.8 , pp. 2123-2130
    • Chang, Y.C.1    Gottlieb, D.I.2
  • 34
    • 0025103048 scopus 로고
    • A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis
    • King D.S., Fields C.G., Fields G.B. A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis. Int. J. Pept. Protein Res. 36:1990;255-266.
    • (1990) Int. J. Pept. Protein Res. , vol.36 , pp. 255-266
    • King, D.S.1    Fields, C.G.2    Fields, G.B.3
  • 35
    • 0023391680 scopus 로고
    • An acid-labile anchoring linkage for solid-phase synthesis of C-terminal peptide amides under mild conditions
    • Albericio F., Barany G. An acid-labile anchoring linkage for solid-phase synthesis of C-terminal peptide amides under mild conditions. Int. J. Pept. Protein Res. 30:1987;206-216.
    • (1987) Int. J. Pept. Protein Res. , vol.30 , pp. 206-216
    • Albericio, F.1    Barany, G.2
  • 36
    • 0029051101 scopus 로고
    • HLA-DQ polymorphisms are highly selective for peptide binding interactions
    • Kwok W.W., Nepom G.T., Raymond F.C. HLA-DQ polymorphisms are highly selective for peptide binding interactions. J. Immunol. 155:1995;2468-2476.
    • (1995) J. Immunol. , vol.155 , pp. 2468-2476
    • Kwok, W.W.1    Nepom, G.T.2    Raymond, F.C.3
  • 38
    • 0028120895 scopus 로고
    • Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones
    • Wucherpfennig K.W., Sette A., Southwood S., Oseroff C., Matsui M., Strominger J.L., Hafler D.A. Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones. J. Exp. Med. 179:1994;279-290.
    • (1994) J. Exp. Med. , vol.179 , pp. 279-290
    • Wucherpfennig, K.W.1    Sette, A.2    Southwood, S.3    Oseroff, C.4    Matsui, M.5    Strominger, J.L.6    Hafler, D.A.7
  • 39
    • 0027389119 scopus 로고
    • Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients
    • Valli A., Sette A., Kappos L., Oseroff C., Sidney J., Miescher G., Hochberger M., Albert E.D., Adorini L. Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients. J. Clin. Invest. 91:1993;616-628.
    • (1993) J. Clin. Invest. , vol.91 , pp. 616-628
    • Valli, A.1    Sette, A.2    Kappos, L.3    Oseroff, C.4    Sidney, J.5    Miescher, G.6    Hochberger, M.7    Albert, E.D.8    Adorini, L.9
  • 40
    • 0028985984 scopus 로고
    • MHC ligands and peptide binding motifs: First listing
    • Rammensee H.G., Friede T., Stefanoviç S. MHC ligands and peptide binding motifs: first listing. Immunogenetics. 41:1995;178-228.
    • (1995) Immunogenetics , vol.41 , pp. 178-228
    • Rammensee, H.G.1    Friede, T.2    Stefanoviç, S.3
  • 42
    • 0025898544 scopus 로고
    • Implication of specific DQB1 alleles in genetic susceptibility and resistance by identification of IDDM siblings with a novel HLA-DQB1 allele and unusual DR2 and DR1 haplotypes
    • Erlich H.A., Griffith R.L., Bugawan T.L., Ziegler R., Alper C., Eisenbarth G. Implication of specific DQB1 alleles in genetic susceptibility and resistance by identification of IDDM siblings with a novel HLA-DQB1 allele and unusual DR2 and DR1 haplotypes. Diabetes. 40:1991;478-480.
    • (1991) Diabetes , vol.40 , pp. 478-480
    • Erlich, H.A.1    Griffith, R.L.2    Bugawan, T.L.3    Ziegler, R.4    Alper, C.5    Eisenbarth, G.6
  • 44
    • 0029979525 scopus 로고    scopus 로고
    • Allele-specific motifs characterize HLA-DQ interactions with a diabetes-associated peptide derived from glutamic acid decarboxylase
    • Kwok W.K., Domeier M.E., Raymond F.C., Byers P., Nepom G.T. Allele-specific motifs characterize HLA-DQ interactions with a diabetes-associated peptide derived from glutamic acid decarboxylase. J. Immunol. 156:1996;2171-2177.
    • (1996) J. Immunol. , vol.156 , pp. 2171-2177
    • Kwok, W.K.1    Domeier, M.E.2    Raymond, F.C.3    Byers, P.4    Nepom, G.T.5
  • 45
    • 0028143519 scopus 로고
    • T cell cross-reactivity between Coxsackie virus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele
    • Tian J., Lehman P.V., Kaufman D.L. T cell cross-reactivity between Coxsackie virus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele. J. Exp. Med. 180:1994;1979-1984.
    • (1994) J. Exp. Med. , vol.180 , pp. 1979-1984
    • Tian, J.1    Lehman, P.V.2    Kaufman, D.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.