Visualization of bisphosphonate-induced caspase-3 activity in apoptotic osteoclasts in vitro

Bone

Volumn 28, Issue 5, 2001, Pages 465-473

  Benford, H L ^a   McGowan, N W A ^a   Helfrich, M H ^a   Nuttall, M E ^b   Rogers, M J ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Apoptosis; Bisphosphonate; Caspase; GGTI 298; Osteoclast; Prenylation

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CASPASE 3; CLODRONIC ACID; ETIDRONIC ACID; GGTI 298; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; PAMIDRONIC ACID; RISEDRONIC ACID; TILUDRONIC ACID; ZOLEDRONIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; OSTEOCLAST; RABBIT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BONE AND BONES; BONE DISEASES, METABOLIC; CASPASE 3; CASPASE 6; CASPASE 7; CASPASES; DIPHOSPHONATES; ENZYME INHIBITORS; FLUORESCENT DYES; HUMANS; NITROGEN; OSTEOCLASTS; PROTEIN ISOPRENYLATION; RABBITS; TUMOR CELLS, CULTURED;

EID: 0035051719     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(01)00412-4     Document Type: Article

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