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Volumn 11, Issue 10, 1996, Pages 1482-1491

Bisphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CLODRONIC ACID; DNA FRAGMENT; ETIDRONIC ACID; GAMMA INTERFERON; IBANDRONIC ACID; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PAMIDRONIC ACID;

EID: 0029766224     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.5650111015     Document Type: Article
Times cited : (196)

References (71)
  • 1
    • 0001219905 scopus 로고
    • Bisphosphonates: A new class of drugs in diseases of bone and calcium metabolism
    • Baker PF (ed.) Springer, Berlin, Germany
    • Fleisch H 1988 Bisphosphonates: A new class of drugs in diseases of bone and calcium metabolism. In: Handbook of Experimental Pharmacology, Vol 83. Baker PF (ed.) Springer, Berlin, Germany, pp. 441-466.
    • (1988) Handbook of Experimental Pharmacology , vol.83 , pp. 441-466
    • Fleisch, H.1
  • 2
    • 0026318521 scopus 로고
    • Bisphosphonates, pharmacology and use in the treatment of tumour-induced hypercalcaemic and metastatic bone disease
    • Fleisch H 1991 Bisphosphonates, pharmacology and use in the treatment of tumour-induced hypercalcaemic and metastatic bone disease. Drugs 42:919-942.
    • (1991) Drugs , vol.42 , pp. 919-942
    • Fleisch, H.1
  • 3
    • 0025366467 scopus 로고
    • Effect of intermittent cyclical etidronate therapy on bone mass and fracture rate in women with postmenopausal osteoporosis
    • Storm T, Thamsborg G, Steiniche T, Genant HK, Sorensen OH 1990. Effect of intermittent cyclical etidronate therapy on bone mass and fracture rate in women with postmenopausal osteoporosis. New Engl J Med 322:1265-1271.
    • (1990) New Engl J Med , vol.322 , pp. 1265-1271
    • Storm, T.1    Thamsborg, G.2    Steiniche, T.3    Genant, H.K.4    Sorensen, O.H.5
  • 5
    • 0015274723 scopus 로고
    • The effects of disodium ethane-1-hydroxy-1,1-diphosphonate on adjuvant induced arthritis in rats
    • Francis MD, Flora L, King WR 1972 The effects of disodium ethane-1-hydroxy-1,1-diphosphonate on adjuvant induced arthritis in rats. Calcif Tissue Res 9:109-121.
    • (1972) Calcif Tissue Res , vol.9 , pp. 109-121
    • Francis, M.D.1    Flora, L.2    King, W.R.3
  • 6
    • 0018595947 scopus 로고
    • Comparative antiinflammatory and bone protective effects of two diphosphonates in adjuvant arthritis
    • Flora L 1979 Comparative antiinflammatory and bone protective effects of two diphosphonates in adjuvant arthritis. Arthritis Rheum 22:340-346.
    • (1979) Arthritis Rheum , vol.22 , pp. 340-346
    • Flora, L.1
  • 7
    • 0022652969 scopus 로고
    • Studies on the chronic phase of adjuvant arthritis: Effect of SR 41319, a new diphosphonate
    • Barbier A, Breliere JC, Remandet B, Roncucci R 1986 Studies on the chronic phase of adjuvant arthritis: effect of SR 41319, a new diphosphonate. Ann Rheum Dis 45:67-74.
    • (1986) Ann Rheum Dis , vol.45 , pp. 67-74
    • Barbier, A.1    Breliere, J.C.2    Remandet, B.3    Roncucci, R.4
  • 8
    • 0024953794 scopus 로고
    • NE 58095: A diphosphonate which prevents bone erosion and preserves joint architecture in experimental arthritis
    • Francis MD, Hovancik K, Boyce RW 1989 NE 58095: A diphosphonate which prevents bone erosion and preserves joint architecture in experimental arthritis. Int J Tissue Reac XI:239-252.
    • (1989) Int J Tissue Reac , vol.11 , pp. 239-252
    • Francis, M.D.1    Hovancik, K.2    Boyce, R.W.3
  • 10
    • 0024428780 scopus 로고
    • The liposome mediated macrophage 'suicide' technique
    • Van Rooijen N 1989 The liposome mediated macrophage 'suicide' technique. J Immunol Meth 124:1-6.
    • (1989) J Immunol Meth , vol.124 , pp. 1-6
    • Van Rooijen, N.1
  • 11
    • 0025240113 scopus 로고
    • Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate
    • Van Rooijen N, Kors N, van den Ende M, Dijkstra CD 1990 Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate. Cell Tissue Res 260:215-222.
    • (1990) Cell Tissue Res , vol.260 , pp. 215-222
    • Van Rooijen, N.1    Kors, N.2    Van Den Ende, M.3    Dijkstra, C.D.4
  • 12
    • 0025015655 scopus 로고
    • Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages
    • Huitinga I, van Rooijen N, de Groot CJA, Uitdehaag BMJ, Dijkstra CD 1990 Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J Exp Med 172:1025-1033.
    • (1990) J Exp Med , vol.172 , pp. 1025-1033
    • Huitinga, I.1    Van Rooijen, N.2    De Groot, C.J.A.3    Uitdehaag, B.M.J.4    Dijkstra, C.D.5
  • 15
    • 0026329441 scopus 로고
    • Inhibition of bone resorption by bisphosphonates: Interactions between bisphosphonates, osteoclasts and bone
    • Flanagan AM, Chambers TJ 1991 Inhibition of bone resorption by bisphosphonates: Interactions between bisphosphonates, osteoclasts and bone. Calcif Tissue Int 49:407-415.
    • (1991) Calcif Tissue Int , vol.49 , pp. 407-415
    • Flanagan, A.M.1    Chambers, T.J.2
  • 16
    • 0025091788 scopus 로고
    • Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro
    • Carano A, Teitelbaum SA, Konsek JD, Schlesinger PH, Blair HC 1990 Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro. J Clin Invest 85:456-461.
    • (1990) J Clin Invest , vol.85 , pp. 456-461
    • Carano, A.1    Teitelbaum, S.A.2    Konsek, J.D.3    Schlesinger, P.H.4    Blair, H.C.5
  • 18
    • 0024406012 scopus 로고
    • Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow
    • Hughes DE, MacDonald BR, Russell RGG, Gowen M 1989 Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow. J Clin Invest 83:1930-1935.
    • (1989) J Clin Invest , vol.83 , pp. 1930-1935
    • Hughes, D.E.1    MacDonald, B.R.2    Russell, R.G.G.3    Gowen, M.4
  • 21
    • 0027193759 scopus 로고
    • Bisphosphonates act on rat bone resorption through the mediation of osteoblasts
    • Sahni M, Guenther H, Fleisch H, Collin P, Martin TJ 1993 Bisphosphonates act on rat bone resorption through the mediation of osteoblasts. J Clin Invest 91:2004-2011.
    • (1993) J Clin Invest , vol.91 , pp. 2004-2011
    • Sahni, M.1    Guenther, H.2    Fleisch, H.3    Collin, P.4    Martin, T.J.5
  • 22
    • 0017280279 scopus 로고
    • The alteration in osteoclast morphology by diphosphonates in bone organ culture
    • Rowe DJ, Hausmann E 1976 The alteration in osteoclast morphology by diphosphonates in bone organ culture. Calcif Tissue Res 20:53-60.
    • (1976) Calcif Tissue Res , vol.20 , pp. 53-60
    • Rowe, D.J.1    Hausmann, E.2
  • 23
    • 0018939767 scopus 로고
    • The effects of calcitonin and colchicine on the cellular response to diphosphonate
    • Rowe DJ, Hausmann E 1980 The effects of calcitonin and colchicine on the cellular response to diphosphonate. Br J Exp Path 61:303-309.
    • (1980) Br J Exp Path , vol.61 , pp. 303-309
    • Rowe, D.J.1    Hausmann, E.2
  • 24
    • 0021049981 scopus 로고
    • Inhibition of bone resorption by difluoromethylene diphosphonate in organ culture
    • Rowe DJ, Hays SJ 1983 Inhibition of bone resorption by difluoromethylene diphosphonate in organ culture. Metab Bone Dis Rel Res 5:13-16.
    • (1983) Metab Bone Dis Rel Res , vol.5 , pp. 13-16
    • Rowe, D.J.1    Hays, S.J.2
  • 28
    • 0028059006 scopus 로고
    • Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum
    • Rogers MJ, Ji X, Russell RGG, Blackburn GM, Williamson MP, Bayless AV, Ebetino FH, Watts DJ 1994 Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum. Biochem J 303:303-311.
    • (1994) Biochem J , vol.303 , pp. 303-311
    • Rogers, M.J.1    Ji, X.2    Rgg, R.3    Blackburn, G.M.4    Williamson, M.P.5    Bayless, A.V.6    Ebetino, F.H.7    Watts, D.J.8
  • 29
    • 0028965149 scopus 로고
    • Structure-activity relationships of new heterocycle-containing bisphosphonates as inhibitors of bone resorption and as inhibitors of growth of Dictyostelium discoideum amoebae
    • Rogers MJ, Xiong X, Brown RJ, Watts DJ, Russell RGG, Bayless AV, Ebetino FH 1995 Structure-activity relationships of new heterocycle-containing bisphosphonates as inhibitors of bone resorption and as inhibitors of growth of Dictyostelium discoideum amoebae. Mol Pharmacol 47:398-402.
    • (1995) Mol Pharmacol , vol.47 , pp. 398-402
    • Rogers, M.J.1    Xiong, X.2    Brown, R.J.3    Watts, D.J.4    Russell, R.G.G.5    Bayless, A.V.6    Ebetino, F.H.7
  • 31
    • 0019170675 scopus 로고
    • Diphosphonates inhibit bone resorption by macrophages in vitro
    • Chambers TJ 1980 Diphosphonates inhibit bone resorption by macrophages in vitro. J Pathol 132:255-262.
    • (1980) J Pathol , vol.132 , pp. 255-262
    • Chambers, T.J.1
  • 33
    • 0022654308 scopus 로고
    • Cytotoxic and migration inhibitory effects of bisphosphonates on macrophages
    • Stevenson PH, Stevenson JR 1986 Cytotoxic and migration inhibitory effects of bisphosphonates on macrophages. Calcif Tissue Int 38:227-233.
    • (1986) Calcif Tissue Int , vol.38 , pp. 227-233
    • Stevenson, P.H.1    Stevenson, J.R.2
  • 34
    • 0023318392 scopus 로고
    • Effect of bisphosphonates on proliferation and viability of mouse bone marrow-derived macrophages
    • Cecchini MG, Felix R, Fleisch H, Cooper PH 1987 Effect of bisphosphonates on proliferation and viability of mouse bone marrow-derived macrophages. J Bone Miner Res 2:135-142.
    • (1987) J Bone Miner Res , vol.2 , pp. 135-142
    • Cecchini, M.G.1    Felix, R.2    Fleisch, H.3    Cooper, P.H.4
  • 35
    • 0025175649 scopus 로고
    • Bisphosphonates in vitro specifically inhibit, among the hematopoietic series, the development of the mouse mononuclear phagocyte lineage
    • Cecchini MG, Fleisch H 1990 Bisphosphonates in vitro specifically inhibit, among the hematopoietic series, the development of the mouse mononuclear phagocyte lineage. J Bone Miner Res 5:1019-1027.
    • (1990) J Bone Miner Res , vol.5 , pp. 1019-1027
    • Cecchini, M.G.1    Fleisch, H.2
  • 36
    • 0025371890 scopus 로고
    • Effects of bisphosphonates on isolated rat osteoclasts as examined by reflected light microscopy
    • Sato M, Grasser W 1990 Effects of bisphosphonates on isolated rat osteoclasts as examined by reflected light microscopy. J Bone Miner Res 5:31-40.
    • (1990) J Bone Miner Res , vol.5 , pp. 31-40
    • Sato, M.1    Grasser, W.2
  • 37
    • 0028154940 scopus 로고
    • Growth inhibition of macrophage-like and other cell types by liposome-encapsulated, calcium-bound and free bisphosphonates in vitro
    • Mönkkönen J, Taskinen M, Auriola SOK, Urtti A 1994 Growth inhibition of macrophage-like and other cell types by liposome-encapsulated, calcium-bound and free bisphosphonates in vitro. J Drug Targetting 2:299-308.
    • (1994) J Drug Targetting , vol.2 , pp. 299-308
    • Mönkkönen, J.1    Taskinen, M.2    Auriola, S.O.K.3    Urtti, A.4
  • 38
    • 0000156360 scopus 로고
    • Osteoclast ontogeny and function
    • Mundy GR, Roodman GD 1987 Osteoclast ontogeny and function. Bone Miner Res 5:209-279.
    • (1987) Bone Miner Res , vol.5 , pp. 209-279
    • Mundy, G.R.1    Roodman, G.D.2
  • 39
    • 0027231742 scopus 로고
    • Nitric oxidemediated apoptosis in murine peritoneal macrophages
    • Albina JE, Cui S, Mateo RB, Reichner JS 1993 Nitric oxidemediated apoptosis in murine peritoneal macrophages. J Immunol 150:5080-5085.
    • (1993) J Immunol , vol.150 , pp. 5080-5085
    • Albina, J.E.1    Cui, S.2    Mateo, R.B.3    Reichner, J.S.4
  • 40
    • 0027186493 scopus 로고
    • Nitric oxide synthase induces macrophage death by apoptosis
    • Sarih M, Souvannavong V, Adam A 1993 Nitric oxide synthase induces macrophage death by apoptosis. Biochem Biophys Res Commun 191:503-508.
    • (1993) Biochem Biophys Res Commun , vol.191 , pp. 503-508
    • Sarih, M.1    Souvannavong, V.2    Adam, A.3
  • 41
    • 0028944339 scopus 로고
    • Nitric oxide-induced apoptosis in RAW264.7 macrophages is antagonized by protein kinase C- and protein kinase A-activating compounds
    • Meßmer UK, Lapetina EG, Brüne B 1995 Nitric oxide-induced apoptosis in RAW264.7 macrophages is antagonized by protein kinase C- and protein kinase A-activating compounds. Mol Pharm 47:757-765.
    • (1995) Mol Pharm , vol.47 , pp. 757-765
    • Meßmer, U.K.1    Lapetina, E.G.2    Brüne, B.3
  • 42
    • 0028294282 scopus 로고
    • Inducible production of nitric oxide in osteoblast-like cells and in fetal mouse bone explants is associated with suppression of osteoclastic bone resorption
    • Löwik CWGM, Nibbering PH, van de Ruit M, Papapoulos SE 1994 Inducible production of nitric oxide in osteoblast-like cells and in fetal mouse bone explants is associated with suppression of osteoclastic bone resorption. J Clin Invest 93:1465-1472.
    • (1994) J Clin Invest , vol.93 , pp. 1465-1472
    • Löwik, C.W.G.M.1    Nibbering, P.H.2    Van De Ruit, M.3    Papapoulos, S.E.4
  • 46
    • 10144247866 scopus 로고
    • Cytokine-induced nitric oxide production inhibits bone resorption in mouse bone marrow cultures by inducing apoptosis in osteoclast progenitors
    • abstract
    • Van't Hof RJ, Ralston SH 1995 Cytokine-induced nitric oxide production inhibits bone resorption in mouse bone marrow cultures by inducing apoptosis in osteoclast progenitors. Bone 17:587 (abstract).
    • (1995) Bone , vol.17 , pp. 587
    • Van't Hof, R.J.1    Ralston, S.H.2
  • 47
    • 0027411984 scopus 로고
    • Apoptosis of S-phase HL-60 cells induced by DNA topoisomerase inhibitors: Detection of DNA strand breaks by flow cytometry using the in situ nick translation assay
    • Gorczyca W, Melamed MR, Darzynkiewicz Z 1993 Apoptosis of S-phase HL-60 cells induced by DNA topoisomerase inhibitors: Detection of DNA strand breaks by flow cytometry using the in situ nick translation assay. Toxicol Letts 67:249-258.
    • (1993) Toxicol Letts , vol.67 , pp. 249-258
    • Gorczyca, W.1    Melamed, M.R.2    Darzynkiewicz, Z.3
  • 48
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RMJ, Higgs EA 1991 Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharm Rev 43:109-142.
    • (1991) Pharm Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 50
  • 52
    • 0024603904 scopus 로고
    • Calcium-activated DNA fragmentation kills immature thymocytes
    • McConkey DJ, Hartzell P, Nicotera P, Orrenius S 1989 Calcium-activated DNA fragmentation kills immature thymocytes. FASEB J 3:1843-1849.
    • (1989) FASEB J , vol.3 , pp. 1843-1849
    • McConkey, D.J.1    Hartzell, P.2    Nicotera, P.3    Orrenius, S.4
  • 53
    • 0028070221 scopus 로고
    • Inhibition of topoisomerase II by aurintricarboxylic acid: Implications for mechanisms of apoptosis
    • Catchpoole DR, Stewart BW 1994 Inhibition of topoisomerase II by aurintricarboxylic acid: implications for mechanisms of apoptosis. Anticancer Res 14:853-856.
    • (1994) Anticancer Res , vol.14 , pp. 853-856
    • Catchpoole, D.R.1    Stewart, B.W.2
  • 54
    • 10144222856 scopus 로고
    • Mammalian chain initiation: The effect of aurintricarboxylic acid
    • Mathews MB 1971 Mammalian chain initiation: The effect of aurintricarboxylic acid. FEBS Letts 15:201-204.
    • (1971) FEBS Letts , vol.15 , pp. 201-204
    • Mathews, M.B.1
  • 58
    • 0028132836 scopus 로고
    • Redox signaling: Nitrosylation and related target interactions of nitric oxide
    • Stamler JS 1994 Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell 78:931-936.
    • (1994) Cell , vol.78 , pp. 931-936
    • Stamler, J.S.1
  • 60
    • 0028913960 scopus 로고
    • Bone cell function, regulation, and communication: A role for nitric oxide
    • Collin-Osdoby P, Nickols GA, Osdoby P 1995 Bone cell function, regulation, and communication: a role for nitric oxide. J Cell Biochem 57:399-408.
    • (1995) J Cell Biochem , vol.57 , pp. 399-408
    • Collin-Osdoby, P.1    Nickols, G.A.2    Osdoby, P.3
  • 61
    • 0018091543 scopus 로고
    • The effects of diphosphonates on the growth and glycolysis of connective-tissue cells in culture
    • Fast DE, Felix R, Dowse C, Neumann WF, Fleisch H 1978 The effects of diphosphonates on the growth and glycolysis of connective-tissue cells in culture. Biochem J 172:97-107.
    • (1978) Biochem J , vol.172 , pp. 97-107
    • Fast, D.E.1    Felix, R.2    Dowse, C.3    Neumann, W.F.4    Fleisch, H.5
  • 63
    • 0019826634 scopus 로고
    • Increase in fatty acid oxidation in calvaria cells cultured with diphosphonates
    • Felix R, Fleisch H 1981 Increase in fatty acid oxidation in calvaria cells cultured with diphosphonates. Biochem J 196:237-245.
    • (1981) Biochem J , vol.196 , pp. 237-245
    • Felix, R.1    Fleisch, H.2
  • 65
    • 0025050661 scopus 로고
    • DNA fragmentation induced in macrophages by gliotoxin does not require protein synthesis and is preceded by raised inositol triphosphate levels
    • Waring P 1990 DNA fragmentation induced in macrophages by gliotoxin does not require protein synthesis and is preceded by raised inositol triphosphate levels. J Biol Chem 265:14476-14480.
    • (1990) J Biol Chem , vol.265 , pp. 14476-14480
    • Waring, P.1
  • 66
    • 0029565958 scopus 로고
    • Long-term amelioration of rat adjuvant arthritis following systemic elimination of macrophages by clodronate-containing liposomes
    • Kinne RW, Schmidt-Weber CB, Hoppe R, Buchner E, Palombo-Kinne E, Nurnberg E, Emmrich F 1995 Long-term amelioration of rat adjuvant arthritis following systemic elimination of macrophages by clodronate-containing liposomes. Arthritis Rheum 38:1777-1790.
    • (1995) Arthritis Rheum , vol.38 , pp. 1777-1790
    • Kinne, R.W.1    Schmidt-Weber, C.B.2    Hoppe, R.3    Buchner, E.4    Palombo-Kinne, E.5    Nurnberg, E.6    Emmrich, F.7
  • 68
    • 0005916684 scopus 로고
    • Bisphosphonates stimulate the production of cytokines by human peripheral blood mononuclear cells in vitro
    • abstract
    • Pioli G, Hughes DE, Mian M, Aarden L, Meager A, Chapman K, Russell RGG 1990 Bisphosphonates stimulate the production of cytokines by human peripheral blood mononuclear cells in vitro. Calcif Tiss Int 46 (Suppl 2):A54 (abstract).
    • (1990) Calcif Tiss Int , vol.46 , Issue.2 SUPPL.
    • Pioli, G.1    Hughes, D.E.2    Mian, M.3    Aarden, L.4    Meager, A.5    Chapman, K.6    Russell, R.G.G.7
  • 70
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
    • Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR 1993 The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75:641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.