Mesenchymal stem cells

Experimental Biology and Medicine

Volumn 226, Issue 6, 2001, Pages 507-520

  Minguell, José J ^a   Erices, Alejandro ^a,b   Conget, Paulette ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b CLÍNICA LAS CONDES   (Chile)

Author keywords

Characteristics mesenchymal progenitors; Human mesenchymal stem cells; Marrow stromal cells; Mesenchymal stem cells; Uncommitted mesenchymal progenitors

Indexed keywords

ADOPTIVE IMMUNOTHERAPY; BONE MARROW CELL; CARTILAGE CELL; CELL MOTILITY; CELL PROLIFERATION; GENE THERAPY; MESENCHYME CELL; MYOTUBE; NERVE CELL; OSTEOBLAST; SHORT SURVEY; STEM CELL;

EID: 0034991924     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: 10.1177/153537020122600603     Document Type: Short Survey

References (172)

1. Bone marrow as a potential source of hepatic oval cells
2. Regulatory mechanisms in stem cell biology
3. Stem cells in the central nervous system
4. Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo
5. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
6. Turning marrow into brain: Generation of glial and neuronal cells from adult bone marrow mesenchymal stem cells
7. Muscle regeneration by bone marrow-derived myogenic progenitors
8. Translating stem and progenitor cell biology to the clinic: Barriers and opportunities
9. Circulation of CD34+ hematopoietic stem cells in the peripheral blood of high-dose cyclophosphamide-treated patients: Enhancement by intravenous recombinant human granulocyte-macrophage colony-stimulating factor
10. Gestational age changes in circulating CD34+ hematopoietic stem/progenitor cells in fetal cord blood
11. Detection of stromal cells in peripheral blood progenitor cell collections from breast cancer patients
12. Mesenchymal progenitor cells in human umbilical cord blood
13. Peripheral blood as an alternative source of mesenchymal stem cells
14. Homing of hemopoietic progenitor cells to the marrow
15. Out of Eden: Stem cells and their niches
16. Stem cell is a stem cell is a stem cell
17. Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt
18. The stromal cells' guide to the stem cell universe
19. Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
20. Stem cell therapy and gene transfer for regeneration
21. Embryonic stem cell lines derived from human blastocysts
22. Derivation of pluripotent stem cells from cultured human primordial germ cells
23. The mesengenic process
24. Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells
25. A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse
26. Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny
27. Characterization of fibroblastic stromal cells from murine bone marrow
28. Factors required for bone marrow fibroblast colony formation in vitro
29. Marrow stromal cells as stem cells for nonhematopoietic tissues
30. Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells
31. Characterization of stromal progenitor cells enriched by flow cytometry
32. Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model
33. Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow
34. Long-term culture of human bone marrow cells
35. Extracellular matriz gene expresión by human bone marrow stroma and by marrow fibroblast
36. Fibroblast precursors in normal and irradiated mouse hematopoietic organs
37. Stem cell factor inhibits erythroid differentiation by modulating the activity of G1-cyclin-dependent kinase complexes: A role for p27 in erythroid differentiation coupled G1 arrest
38. Growth kinetics, selfrenewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryo-preservation
39. Propagation and senescence of human marrow stromal cells in culture: A simple colony-formaing assay identifies samples with the greatest potential to propagate and differentiate
40. Donor variation in the growth propierties and osteogenic potential of human marrow stromal cells
41. Large-scale recovery and characterization of stromal cell-associated primitive haemopoietic progenitor cells from filter-retained human bone marrow
42. Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases
43. Stromal damage as consequence of high-dose chemo/radiotherapy in bone marrow transplant recipients
44. Multilineage potential of adult human mesenchymal stem cells
45. Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies
46. Monoclonal antibodies reactive with human osteogenic cell surface antigens
47. Stromal cells from human long-term marrow cultures are mesenchymal cells that differentiate following a vascular smooth muscle differentiation pathway
48. Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, Stro-1
49. The growth factor requirements of STRO-1-positive human marrow stromal precursors under-deprived conditions in vitro
50. Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL-1 alpha
51. The extracellular matrix of the hematopoietic microenvironment
52. Human mesenchymal stem cells provide stromal support for efficient CD34+ transduction
53. Human mesenchymal stem cells support megakaryocyte and pro-platelet formation from CD34(+) hematopoietic progenitor cells
54. Is hyaluronic acid the "organizer" of the extracellular matrix in marrow stroma?
55. Spatial and temporal distribution of CD44 and osteopontin in fracture callus
56. The origin of bone formed in composite grafts of porous calcium phosphate ceramic loaded with marrow cells
57. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice
58. Culture expanded canine mesenchymal stem cells possess osteochondrogenic potential in vivo and in vitro
59. Marrow-derived progenitor cell injections enhance new bone formation during distraction
60. Transplant of bone marrow- and musclederived connective tissue cultures in diffusion chambers for biossay of bone marrow morphogenetic protein
61. Use of mesenchymal stem cells in a collagen matrix for Achilles tendon repair
62. Autologous mesenchymal stem cell-mediated repair of tendon
63. Functional isolation and characterization of human hematopoietic stem cells
64. Cell cycle analysis by flow and laser scanning cytometry
65. Antitumor activity of antizyme which targets the ornithine decarboxylase (ODC) required for cell growth and transformation
66. In vivo and in vitro characterization of long-term repopulating primitive hematopoiectic cells isolated by sequential Hoechst 33342-rhodamine 123 FACS selection
67. Prolonged expression of the c-kit receptor in germ cells of intersex fetal testes
68. De novo adipogenesis in mice at site of injection of basement membrane and basic fibroblasts growth factor
69. Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures
70. Development and characterization of conditionally immortalized osteoblast precursor cell lines from human bone marrow stroma
71. Analysis of the developmental potential of conditionally immortal marrow-derived mesenchymal progenitor cells isolated from the H-2Kb-tsA58 transgenic mouse
72. Cell cycles in cell hierarchies
73. Expansion of haematopoietic stem cells in vitro: A challenge to stem cell biologists
74. Stem cells: The intestinal stem cell as a paradigm
75. Hematopoietic stem cells and microenvironment: The proliferation and differentiation of stromal cells
76. Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells
77. Cell therapy: Achievements and perspectives
78. Cells isolated from adult human skeletal muscle capable of differentiating into multiple mesodermal phenotypes
79. Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bonederived clonal cell population: Effect of dexamethasone
80. Dynamics of myoblast transplantation reveal a discrete minority of precursors with stem cell-like properties as the myogenic source
81. Cell heterogeneity upon myogenic differentiation: Down-regulation of MyoD and Myf-5 generates reserve cells
82. Heterogeneity in the progeny of single human muscle satellite cells
83. Muscle precursor cells injected into irradiated mdx mouse muscle persist after serial injury
84. Satellite cell proliferative compartments in growing skeletal muscles
85. A population of cells isolated from rat heart capable of differentiating into several mesodermal phenotypes
86. Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: Implications for osteopenic disorders
87. Continuously growing bipotential and monopotential myogenic, adipogenic, and chondrogenic subclones isolated from the multipotential RCJ 3.1 clonal cell line
88. Stromal mesenchymal progenitor cells
89. Simultaneous detection of multiple bone-related mRNAs and protein expression during osteoblast differentiation: Polymerase chain reaction and immunocyto-chemical studies at the single cell level
90. Principles of cartilage repair and regeneration
91. Evidence for insufficient chondrocytic differentiation during repair of full-thickness defects of articular cartilage
92. Beneficial effect of basic fibroblast growth factor on the repair of full-thickness defects in rabbit articular cartilage
93. Bone morphogenetic protein-2 does not alter the differentiation pathway of committed progenitors of osteoblasts and chondroblasts
94. Developmental restriction of embryonic calvarial cell populations as characterized by their in vitro potential for chondrogenic differentiation
95. Characterization of the cells in the repair tissue of full-thickness articular cartilage defects
96. Cartilage tissue differentiation from mesenchymal cells derived from mature muscle in tissue culture
97. Cell origin and differentiation in the repair of full-thickness defects of articular cartilage
98. Osteochondral progenitor cells in acute and chronic canine non-unions
99. Culture and characterization of juvenile rabbit tenocytes
100. Intrinsic tendon cell proliferation in tissue culture
101. Matrix synthesis and cell proliferation in repaired flexor tendons within e-PTFE reconstructed flexor tendon sheaths
102. Effects of hyaluronan on cell proliferation and collagen synthesis: A study of rabbit flexor tendons in vitro
103. Similar effects of recombinant human insulin-like growth factor-I and II on cellular activities in flexor tendons of young rabbits: Experimental studies in vitro
104. Ideal concentration of growth factors in rabbit's flexor tendon culture
105. Proliferation and differentiation of brown adipocytes from interstitial cells during cold acclimation
106. Impaired adipogenesis in insulin-like growth factor binding protein-1 transgenic mice
107. Ultrastructural analysis of differentiation of rat endoderm in vitro: Adipose vascular-stromal cells induce endoderm differentiation, which in turn induces differentiation of the vascular-stromal cells into chondrocytes
108. Interconversion potential of cloned human marrow adipocytes in vitro
109. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
110. Characterization of human bone marrow stromal cells with respect to osteoblastic differentiation
111. Agerelated osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow
112. Developmental changes in the function of hematopoietic stem cells
113. Transplantation of bone marrow fibroblastoid stromal cells in mice via the intravenous route
114. Failure to detect spindle-shaped fibroblastoid cell progenitors in PBPC collections
115. Human bone marrow-derived mesenchymal (stromal) progenitor cells (MPCs) cannot be recovered from peripheral blood progenitor cell collections
116. A cell-based gene therapy targeting fracture repair
117. Granulocyte-macrophage colony stimulating factor expands the circulating haemopoietic progenitor cell compartment in man
118. Cells with osteoblastic phenotypes can be explanted from human gingiva and periodontal ligament
119. Epidermal stem cells: Markers, patterning and the control of stem cell fate
120. Stimulation of differentiation and proliferation of hematopoietic cells in vitro
121. Stem cells in epithelial tissues
122. Mammalian neural stem cells
123. Direct bone induction in the subperiosteal space of rat clavaria demineralized bone allografts
124. Development of a human adipocyte synthetic polymer scafflod
125. Hyaluronic acidbased polymers as cell carriers for tissue-engineered repair of bone and cartilage
126. Organization of extracellular matrix components during differentiation of adipocytes in long-term cultures
127. Autologous mesenchymal progenitor cells in articular cartilage repair
128. The homing of hematopoietic stem cells to the bone marrow
129. Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy
130. Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation
131. Donor origin of the in vitro haematopoietic microenvironment after marrow transplantation in man
132. Host origin of marrow stromal cells following allogeneic bone marrow transplantation
133. Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta
134. Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero
135. Cell cycle-related changes in repopulating capacity of human mobilized peripheral blood CD34(+) cells in non-obese diabetic/severe combined immune-deficient mice
136. Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): Implications for therapeutic use
137. Mesenchymal stem cells: No longer second class marrow citizens
138. Abnormal osteogenesis in osteoporotic patients is reflected by altered mesenchymal stem cells dynamics
139. Selective interactions between epithelial turnout cells and bone marrow mesenchymal stem cells
140. High-efficiency transduction and long-term gene expression with a murine stem cell retroviral vector encoding the green fluorescent protein in human marrow stromal cells
141. Gene therapy: Adenovirus-mediated human bone morphogenetic protein-2 gene transfer induces mesenchymal progenitor cell proliferation and differentiation in vitro and bone formation in vivo
142. Effect of bone morphogenetic protein-12 gene transfer on mesenchymal progenitor cells
143. Adenoviral-mediated gene transfer into ex vivo expanded human bone marrow mesenchymal progenitor cells
144. Mesenchymal progenitor cells: Biology and clinical utilization
145. Dystrophin expression in the mdx mouse restored by stem cell transplantation
146. Neural stem cells: From cell biology to cell replacement
147. Neural stem cells
148. Epithelial stem cell repertoire in the gut: Clues to the origin of cell lineages, proliferative units and cancer
149. Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters
150. A modified culture system for epidermal cells for grafting purposes: An in vitro and in vivo study
151. Receptor tyrosine kinase expression in human boen marrow stromal cells
152. Mesenchymal stem cell surface antigen SB-10 corresponds to activated leukocyte cell adhesion molecule and is involved in osteogenic differentiation
153. Differentiation of human marrow stromal precursor cells: Bone morphogenetic protein-2 increases OSF2/CBFA1, enhances osteoblast commitment, and inhibits late adipocyte maturation
154. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
155. Extracellular factors, signalling pathways and differentiation of adipose precursor cells
156. Osf2/Cbfal: A transcriptional activator of osteoblast differentiation
157. Molecular mechanism mediating proliferation/differentiation interrrelationships during progressive development of the osteoblast phenotype
158. Marrow stromal stem cells
159. Human mesenchymal stem cells promote human osteoclast differentiation from CD34+ bone marrow hematopoietic progenitors
160. Myogenic cells derived from rat bone marrow mesenchymal stromal cells exposed to 5-azacytidine
161. Skeletal, smooth and cardiac muscle differentiation from single adult marrow derived mesodermal progenitor cells
162. Bcl-2 expression identifies an early stage of myogenesis and promotes clonal expansion of muscle cells
163. 1,25-Dihydroxy vitamin D3 inhibits adipocytes differentiation and gene expression in murine bone marrow stromal cell clones and primary cultures
164. The anabolic effect of PGE2 in rat bone marrow cultures is mediated via the EP4 receptor subtype
165. Growth hormone, osteoblasts, and marrow adipocytes: A case report
166. Leukemia inhibitor factor and its receptor promote adipocyte differentiation via the mitogen-activated protein kinase cascade
167. Interleukin-6-type cytokines stimulate mesenchymal progenitor differentiation toward the osteoblastic lineage
168. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes
169. Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2Cl2 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation
170. Bone morphogenetic proteins inhibit adipocyte differentiation by bone marrow stromal cells
171. Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages
172. Atherogenic diet and minimally oxidized low-density lipoprotein inhibit osteogenic and promote adipogenic differentiation of marrow stromal cells