Effect of bone morphogenetic protein-12 gene transfer on mesenchymal progenitor cells

Clinical Orthopaedics and Related Research

Volumn 369, Issue , 1999, Pages 333-339

  Lou, Jueren ^a   Tu, Yizheng ^a   Ludwig, Fredrick J ^a   Zhang, Jingfan ^a   Manske, Paul R ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CARTILAGE; CELL DIFFERENTIATION; CELL LINEAGE; ENZYME ACTIVITY; GENE TRANSFER; MESENCHYME CELL; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TENDON;

EID: 0032804051     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1097/00003086-199912000-00035     Document Type: Article

References (23)

1. Celeste AJ, Iannazzi JA, Taylor RC, et al: Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone. Proc Natl Acad Sci USA 87:9843-9847, 1990.
2. Celeste AJ, Ross AJ, Yamaji N, Wozney JM: The molecular cloning of human bone morphogenetic proteins-10,-11,-12, three new members of the transforming growth factor-β superfamily. J Bone Miner Res 10(Suppl 1): S336, 1995. Abstract.
3. Dube JL, Celeste AJ: Human bone morphogenetic protein-13, a molecule which is highly related to human bone morphogenetic-12. J Bone Miner Res 10(Suppl 1): S336, 1995. Abstract.
4. Gazit D, Ebner R, Kahn AJ, Derynck R: Modulation of expression and cell surface binding of members of the transforming growth factor-β superfamily during retinoic acid-induced osteoblastic differentiation of multipotential mesenchymal cells. Mol Endocrinol 7:189-198, 1993.
5. Horwitz MS, Tufariello J, Grunhaus A, Fejer G: Model system for studying the effects of adenovirus E3 gene on virulence in vivo. Curr Top Microbiol Immunol 99:195-211, 1995.
6. Inada M, Katagiri T, Akiyama S, et al: Bone morphogenetic protein-12 and -13 inhibit terminal differentiation of myoblasts, but do not include their differentiation into osteoblasts. Biochem Biophys Res Comm 222:317-322, 1996.
7. Katagiri T, Yamaguchi A, Ikeda T, et al: The non-osteogenic mouse pluripotent cell line, C3H 10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenic protein-2. Biochem Biophys Res Commun 172:295-299, 1990.
8. Lou J, Xu F, Merkel K, Manske PR: Gene therapy: Adenovirus mediated human BMP-2 gene transfer induces mesenchymal progenitor cell proliferation and differentiation in vitro and bone formation in vivo. J Orthop Res 17:43-50, 1999.
9. Lou J, Manske PR, Aoki M, Joyce M: Adenovirus mediated gene transfer into tendon and tendon sheath. J Orthop Res 14:513-517, 1996.
10. Luyten FP, Cunningham NS, Ma S, et al: Purification and partial amino acid sequence of osteogenin, a protein differentiating bone differentiation. J Biol Chem 264:13377-13380, 1989.
11. Ozkaynak E, Rueger DC, Drier EA, et al: OP-1 cDNA encodes an osteogenic protein in the TGF-β family. EMBO J 9:2085-2093, 1990.
12. Preece A: Paraffin Tissue Processing Method. In Preece A (ed). A Manual for Histologic Technicians. Boston. Little, Brown and Company 57-73, 1992.
13. Reddi AH: Cell biology and biochemistry of endochondral bone development. Coll Rel Res 1:209-226, 1981.
14. Sampath TK, Coughlin JE, Whetsone RM, et al: Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth-β superfamily. J Biol Chem 265:13198-13205, 1990.
15. Taylor SM, Jones PA: Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell 17:771-779, 1979.
16. Urist MR: Bone: Formation by autoinduction. Science 50:893-899, 1965.
17. Wang EA, Rosen V, Cordes P, et al: Purification and characterization of other distinct bone-inducing factors. Proc Natl Acad Sci USA 85:9484-9488, 1988.
18. Wolfman NM, Celeste AJ, Cox K, et al: Preliminary characterization of the biological activities of rhBMP-12. J Bone Miner Res 10(Suppl 1):S148, 1995. Abstract.
19. Wolfman NM, Hattersley G, Cox K, et al: Ectopic induction of tendon and ligament in rats by growth and differentiation factor 5, 6, 7, members of the TGF-β gene family. J Clin Invest 100:321-330, 1997.
20. Wozney JM: The bone morphogenetic proteins. Prog Growth Factor Res 1:267-280, 1989.
21. Wozney JM: The bone morphogenetic protein family. Multifunctional cellular regulators in the embryo and adult Eur J Oral Sci 106(Suppl 10):160-166, 1998.
22. Wozney JM, Rosen V: Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair. Clin Orthop 346:26-37, 1998.
23. Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ: Novel regulators of bone formation: Molecular clones and activities. Science 242:1528-1534, 1988.