Biology and clinical utilization of mesenchymal progenitor cells

Brazilian Journal of Medical and Biological Research

Volumn 33, Issue 8, 2000, Pages 881-887

  Minguell, J J ^a,b   Conget, P ^a   Erices, A ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b CLÍNICA LAS CONDES   (Chile)

Author keywords

Differentiation; Mesenchymal progenitor cells; Transplantation

Indexed keywords

ANIMAL; BONE MARROW CELL; CELL TRANSPLANTATION; CYTOLOGY; HUMAN; MESODERM; METHODOLOGY; PHYSIOLOGY; REVIEW; STEM CELL; STEM CELL TRANSPLANTATION;

ANIMALS; BONE MARROW CELLS; CELL TRANSPLANTATION; HUMANS; MESODERM; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 0034244385     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2000000800003     Document Type: Article

References (62)

1. Friedenstein AJ, Gorskaja JF & Kulagina NN (1976). Fibroblast precursors in normal and irradiated mouse hematopoietic organs. Experimental Hematology, 4: 267-274.
2. Castro-Malaspina H, Gay RE, Resnick G, Kapoor N, Meyers P, Chiarieri D, McKenzie S, Broxmeyer HE & Moore MA (1980). Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny. Blood, 56: 289-301.
3. Owen M (1988). Marrow stromal stem cells. Journal of Cell Science (Suppl), 10: 63-76.
4. Caplan AI (1994). The mesengenic process. Clinics in Plastic Surgery, 21: 429-435
5. Prockop DJ (1997). Marrow stromal cells as stem cells for nonhematopoietic tissues. Science, 276: 71-74.
6. Bordignon C, Carlo-Stella C, Colombo MP, De Vincentns A, Lanata L, Lemoli RM, Locatelli F, Olivieri A, Rondeili D, Zanon P & Tura S (1999). Cell therapy: achievements and perspectives. Haematologica, 84: 1110-1149.
7. Kuznetsov SA, Friedenstein AJ & Robey PG (1997). Factors required for bone marrow fibrobfast colony formation in vitro. British Journal of Haematology, 97: 561-570.
8. Conget F & Minguell JJ (2000). Adenoviral-mediated gene transfer into ex vivo expanded human bone marrow mesenchymal progenitor cells. Experimental Hematology, 28: 382-390.
9. Piltenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S & Marshak DR (1999). Multihneage potential of adult human mesenchymal stem cells. Science, 284: 143-147.
10. Pereira RF, Halford KW, O'Hara MD, Leeper DB, Sokolov BP, Pollard MD, Bagasra O & Prockop DJ (1995). Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice. Proceedings of the National Academy of Sciences, USA, 92: 4857-4861.
11. Dennis JE, Merriam A, Awadallah A, Yoo JU, Johnstone B & Caplan AI (1999). A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse. Journal of Bone and Mineral Research, 14: 700-709.
12. Beresford JN, Bennett JH, Devlin C, Leboy PS & Owen ME (1992). Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures. Journal of Cell Science, 102: 341-351.
13. Awad HA, Butler DL, Boivin GP, Smith FN, Malaviya P, Huibregtse B & Caplan AI (1999). Autologous mesenchymal stem cell-mediated repair of tendon. Tissue Engineering, 5: 267-277.
14. Galmiche MC, Koteliansky VE, Briere J, Herve P & Charbord P (1993). Stromal cells from human long-term marrow cultures are mesenchymal cells that differentiate following a vascular smooth muscle differentiation pathway. Blood, 82: 66-76.
15. Wakitani S, Saito T & Caplan AI (1995). Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine. Muscle and Nerve, 18: 1417-1426.
16. Kopen GC, Prockop DJ & Phinney DG (1999). Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proceedings of the National Academy of Sciences, USA, 96: 10711-10716.
17. Gartner S & Kaplan HS (1980). Long-term culture of human bone marrow cells. Proceedings of the National Academy of Sciences, USA, 77: 4756-4759.
18. Majumdar MK, Thiede MA, Mosca JD, Moorman M & Gerson SL (1998). Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MPCs) and stromal cells. Journal of Cellular Physiology, 176: 57-66.
19. Chichester CO, Fernandez M & Minguell JJ (1993). Extracellular matrix gene expression by human bone marrow stroma and by marrow fibroblasts. Cell Adhesion and Communication, 1: 93-99.
20. Conget PA & Minguell JJ (1999). Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells. Journal of Cellular Physiology, 181: 67-73.
21. Phinney DG, Kopen G, Righter W, Webster S, Tremain N & Prockop DJ (1999). Donor variation in the growth properties and osteogenic potential of human marrow stromal cells. Journal of Cellular Biochemistry, 75: 424-436.
22. Digirolamo CM, Stokes D, Colter D, Phinney DG, Class R & Prockop DJ (1999). Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate. British Journal of Haematology, 107: 275-281.
23. Bruder SP, Jaiswal N & Haynesworth SE (1997). Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation. Journal of Cellular Biochemistry, 64: 278-294.
24. Haynesworth SE, Baber MA & Caplan AI (1992). Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies. Bone, 13: 69-80.
25. Gerson SL (1999). Mesenchymal stem cells: no longer second class marrow citizens. Nature Medicine, 5: 262-263.
26. Haynesworth SE, Baber MA & Caplar AI (1996). Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1 alpha. Journal of Cellular Physiology, 166: 585-592.
27. Sale GE & Storb R (1983). Bilateral diffuse pulmonary ectopic ossification after marrow allograft in a dog. Evidence for allotransplantation of hemopoietic and mesenchymal stem cells. Experimental Hematotogy, 11: 961-966.
28. Richards M, Huibregtse BA, Caplan AI, Goulet JA & Goldstein SA (1999). Marrow-derived progenitor cell injections enhance new bone formation during distraction. Journal of Orthopaedic Research, 17: 900-908.
29. Kadiyala S, Young RG, Thiede MA & Bruder SP (1997). Culture expanded canine mesenchymal stem cells possess osteochondrogenic potential in vivo and in vitro. Cell Transplantation, 6: 125-134.
30. Goshima J, Goldberg VM & Caplan AI (1991). The origin of bone formed in composite grafts of porous calcium phosphate ceramic loaded with marrow cells. Clinical Orthopaedics and Related Research, 269: 274-283.
31. Kataoka H & Urist MR (1993). Transplant of bone marrow and muscle-derived connective tissue cultures in diffusion chambers for bioassay of bone marrow morphogenetic protein. Clinical Orthopaedics and Related Research, 286: 262-270.
32. Young RG, Butler DL, Weber W, Caplan AI, Gordon SL & Fink DJ (1998). Use of mesenchymal stem cells in a collagen matrix for Achilles tendon repair. Journal of Orthopaedic Research, 16: 406-413.
33. Ferrari G, Cusella-De Angelis G, Coletta M, Paolucci E, Stornaiuolo A, Cossu G & Mavilio F (1998). Muscle regeneration by bone marrow-derived myogenic progenitors. Science, 279: 1528-1530.
34. Weissman IL (2000). Translating stem and progenitor cell biology to the clinic: barriers and opportunities. Science, 287: 1442-1446.
35. Jaiswal N, Haynesworth SE, Caplan AI & Bruder SP (1997). Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. Journal of Cellular Biochemistry, 64: 295-312.
36. Ducy P, Zhang R, Geoffroy V, Ridall AL & Karsenty G (1997). Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell, 89: 743-754.
37. Tontonoz P, Hu E & Spiegelman BM (1994). Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell, 79: 1147-1156.
38. Gori F, Thomas T, Hicok KC, Spelsberg TC & Riggs BL (1999). Differentiation of human marrow stromal precursor cells: bone morphogenetic protein-2 increases OSF2/CBFA1, enhances osteoblast commitment, and inhibits late adipocyte maturation. Journal of Bone and Mineral Research, 14: 1522-1535.
39. Bruder SP, Horowitz MC, Mosca JD & Haynesworth SE (1997). Monoclonal antibodies reactive with human osteogenic cell surface antigens. Bone, 21: 225-235.
40. Erices A, Conget P & Minguell JJ (2000). Mesenchymal progenitor cells in human umblical cord blood. British Journal of Haematology (in press).
41. Shields LE & Andrews RG (1998). Gestational age changes in circulating CD34+ hematopoietic stem/progenitor cells in fetal cord blood. American Journal of Obstetrics and Gynecology, 178: 931-937.
42. Tavassoli M (1991). Embryonic and fetal hemopoiesis: an overview Blood Cells, 1 269-281.
43. Piersma AH, Ploemacher RE & Brockbank KG (1983). Transplantation of bone marrow fibroblastoid stromal cells in mice via the intravenous route. British Journal of Haematology, 54: 285-290.
44. Fernandez M, Simon V, Herrera G, Cao C. Del Favero H & Minguell JJ (1997). Detection of stromal cells in peripheral blood progenitor cell collections from breast cancer patients. Bone Marrow Transplantation, 20: 265-271.
45. Lazarus HM, Haynesworth SE, Gerson SL & Caplan AI (1997). Human bone marrow-derived mesenchymal (stromal) progenitor cells (MPCs) cannot be recovered from peripheral blood progenitor cell collections. Journal of Hematotherapy, 6: 447-455.
46. Ojeda-Uribe M, Brunot A, Lenat A & Legros M (1993). Failure to detect spindle-shaped fibroblastoid cell progenitors in PBPC collections. Acta Haematologica, 90: 139-143.
47. Johnstone B & Yoo JU (1999). Autologous mesenchymal progenitor cells in articular cartilage repair. Clinical Orthopaedics and Related Research, 367 (Suppl): S156-S162.
48. Pereira RF, O'Hara MD, Laptev AV, Halford KW, Pollard MD, Class R, Simon D, Livezey K & Prockop DJ (1998). Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogeness imperfecta. Proceedings of the National Academy of Sciences, USA, 95: 1142-1147.
49. Koc ON, Gerson SL, Cooper BW, Dyhouse SM, Haynesworth SE, Caplan AI & Lazarus HM (2000). Rapid hematopoietic recovery after coinfusion of autologousblood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. Journal of Clinical Oncology, 18: 307-316.
50. Koc ON, Peters C, Aubourg P, Raghavan S, Dyhouse S, DeGasperi R, Kolodny EH, Yoseph YB, Gerson SL, Lazarus HM, Caplan AI, Watkins PA & Krivit W (1999). Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases Experimental Hematology, 27: 1675-1681.
51. Simmonds PJ, Przepiorka ED, Thomas ED & Torok-Storb B (1987). Host origin of marrow stromal cells following allogeneic bone marrow transplantation. Nature, 328; 429-432.
52. Galotto M, Berisso G, Delfino L, Podesta M, Ottaggio L, Dallorso S, Dufour C, Ferrara GB, Abbondandolo A, Dim G, Bacigalupo A, Cancedda R & Quarto R (1999). Stromal damage as consequence of high-dose chemo/radiotherapy in bone marrow transplant recipients. Experimental Hematology, 27: 1460-1466.
53. Almeida-Porada G, Flake AW, Glimp HA & Zanjam ED (1999). Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero. Experimental Hematology, 27: 1569-1575.
54. Keating A, Singer JW, Killen PD, Striker GE, Salo AC, Sanders J, Thomas ED, Thorning D & Fialkow PJ (1982). Donor origin of the in vitro haematopoietic microenvironment after marrow transplantation in man. Nature, 298: 280-283.
55. Blazsek I, Delmas Marsalet B, Legras S, Marion S, Machover D & Misset JL (1999). Large scale recovery and characterization of stromal cell-associated primitive haemopoietic progenitor cells from filter-retained human bone marrow. Bone Marrow Transplantation, 23: 647-657.
56. Gothot A, van der Loo JC, Clapp DW & Srour EF (1998). Cell cycle-related changes in repopulating capacity of human mobilized peripheral blood CD34(+) cells in non-obese diabetic/severe combined immune-deficient mice. Blood, 92: 2641-2649.
57. Beauchamp JR, Morgan JE, Pagel CN & Partridge TA (1999). Dynamics of myoblast transplantation reveal a discrete minority of precursors with stem cell-like properties as the myogenic source. Journal of Cell Biology, 144: 1113-1122.
58. Lazarus HM, Haynesworth SE, Gerson SL, Rosenthal NS & Caplan AI (1995). Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use. Bone Marrow Transplantation, 16: 557-564.
59. Horwitz EM, Prockop DJ, Fitzpatrick LA, Koo WW, Gordon PL, Neel M, Sussman M, Orchard P, Marx JC, Pyeritz RE & Brenner MK (1999). Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nature Medicine, 5: 309-313.
60. Kang MI, Lee WY, Oh KW, Han JH, Song KH, Cha BY, Lee KW, Son HY, Kang SK & Kim CC (2000). The short-term changes of bone mineral metabolism following bone marrow transplantation. Bone, 26: 275-279.
61. Marx JC, Allay JA, Persons DA, Nooner SA, Hargrove PW, Kelly PF, Vanin EF & Horwitz EM (1999). High-efficiency transduction and long-term gene expression with a murine stem cell retroviral vector encoding the green fluorescent protein in human marrow stromal cells. Human Gene Therapy, 10: 1163-1173.
62. Lou J, Xu F, Merkel K & Manske P (1999). Gene therapy: adenovirus-mediated human bone morphogenetic protein-2 gene transfer induces mesenchymal progenitor cell proliferation and differentiation in vitro and bone formation in vivo. Journal of Orthopaedic Research, 17: 43-50.