In vivo delivery to tumors of DNA complexed with linear polyethylenimine

Human Gene Therapy

Volumn 10, Issue 10, 1999, Pages 1659-1666

  Coll, Jean Luc ^a   Chollet, Patrice ^a   Brambilla, Elisabeth ^a   Desplanques, Dominique ^a   Behr, Jean Paul ^b   Favrot, Marie ^a  

^a INSTITUT ALBERT BONNIOT   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AZIRIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; FEMALE; GENE TARGETING; GENETIC TRANSFECTION; LUNG; LUNG METASTASIS; MOUSE; NONHUMAN; PSEUDOCYST; REPORTER GENE; SOLID TUMOR; TUMOR CELL;

EID: 0033166095     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950017662     Document Type: Article

References (21)

1. ABDALLAH, B., HASSAN, A., BENOIST, C., GOULA, D., BEHR, J.P., and DEMENEIX, B.A. (1996). A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: Polyethylenimine. Hum. Gene Ther. 7, 1947-1954.
2. BALASUBRAMANIAM, R.P., BENNETT, M.J., ABERLE, A.M., MALONE, J.G., NANTZ, M.H., and MALONE, R.W. (1996). Structural and functional analysis of cationic transfection lipids: The hydrophobic domain. Gene Ther. 3, 163-172.
3. BOUSSIF, O., LEZOUALC'H, F., ZANTA, M.A., MERGNY, M.D., SCHERMAN, D., DEMENEIX, B., and BEHR, J.P. (1995). A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc. Natl. Acad. Sci. U.S.A. 92, 7297-7301.
4. BOUSSIF, O., ZANTA, M.A., and BEHR, J.P. (1996). Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold. Gene Ther. 3, 1074-1080.
5. COLL, J.L., NEGOESCU, A., LOUIS, N., SACHS, L., TENAUD, C., GIRARDOT, V., DEMEINEX, B., BRAMBILLA, E., BRAMBILLA, C., and FAVROT, M. (1998). Antitumor activity of bax and p53 naked gene transfer in lung cancer: In vitro and in vivo analysis. Hum. Gene Ther. 9, 2063-2074.
6. EGILMEZ, N.K., YOSHIMI, I., and BANKERT, R.B. (1996). Evaluation and optimization of different cationic liposome formulations for in vivo gene transfer. Biochem. Biophys. Res. Commun. 221, 169-173.
7. GOLDMAN, C.K., SOROCEANU, L., SMITH, N., GILLESPIE, Y.C., SHAW, W., BURGESS, S., BILBAO, G., and CURIEL, D.T. (1997). In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer. Nature Biotechnol. 15, 462-466.
8. GOULA, D., BENOIST, C., MANTERO, S., MERLO, G., LEVI, G., and DEMENEIX, B.A. (1998a). Polyethylenimine-based intravenous delivery of transgenes to mouse lung. Gene Ther. 5, 1291-1295.
9. GOULA, D., REMY, J.S., ERBACHER, P., WASOWICZ, M., LEVI, G., ABDALLAH, B., and DEMENEIX, B.A. (1998b). Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system. Gene Ther. 5, 712-717.
10. KOLTOVER, I., SALDITT, T., RÄDLER, J.O., and SAFINYA, C.R. (1998). An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery. Nature (London) 281, 78-81.
11. LABAT-MOLEUR, F., STEFFAN, A.M., BRISSON, C., PERRON, H., FEUGEAS, O., FURSTENBERGER, P., OBERLING, F., BRAMBILLA, E., and BEHR, J.P. (1996). An electron microscopy study into the mechanism of gene transfer with lipopolyamines. Gene Ther. 3, 1010-1017.
12. LI, S., RIZZO, M.A., BATTACHARYA, S., and HUANG, L. (1998). Characterization of cationic lipid-protamine-DNA (LPD complexes) for intravenous gene delivery. Gene Ther. 5, 930-937.
13. LIU, Y., MOUNKES, L.C., LIGGITT, H.D., BROWN, C.S., SOLODIN, I., HEATH, T.D., and DEBS, R.J. (1997). Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery. Nature Biotechnol. 15, 167-173.
14. LOLLINI, P.L., DE GIOVANNI, C., LANDUZZI, L., NICOLETTI, G., FRABETTI, F., CAVALLO, F., GIOVARELLI, M., FORNI, G., MODICA, A., MODESTI, A., MUSIANI, P., and NANNI, P. (1995). Transduction of genes coding for a histocompatibility (MHC) antigen and for its physiological inducer interferon-γ in the same cell: Efficient MHC expression and inhibition of tumor and metastasis growth. Hum. Gene Ther. 6, 743-752.
15. NABEL, G.J., NABEL, E.G., YANG, Z.Y., FOX, B.A., PLAUTZ, G., GAO, X., HUANG, L., SHU, S., GORDON, D., and CHANG, A.E. (1993). Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans. Proc. Natl. Acad. Sci. U.S.A. 90, 11307-11311.
16. POLLARD, H., REMY, J.S., LOUSSOUARN, G., DEMOLOMBE, S., BEHR, J.P., and ESCANDE, D. (1998). Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J. Biol. Chem. 273, 7507-7511.
17. STEWART, M.J., PLAUTZ, G., DEL BUONO, L., YANG, Z.Y., XU, L., GAO, X., HUANG, L., NABEL, E.G., and NABEL, G.J. (1992). Gene transfer in vivo with DNA-liposome complexes: Safety and acute toxicity in mice. Hum. Gene Ther. 3, 267-275.
18. TEMPLETON, N.S., LASIC, D.P., FREDERIK, P.M., STREY, H.H., ROBERTS, D.D., and PAVLAKIS, G.N. (1997). Improved DNA: liposome complexes for increased systemic delivery and gene expression. Nature Biotechnol. 15, 647-652.
19. THURSTON, C., McLEAN, J.W., RIZEN, M., BALUK, P., HASKELL, A., MURPHY, T.J., HANAHAN, D., and McDONALD, D.M. (1998). Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice. J. Clin. Invest. 101, 1401-1413.
20. ZHU, J., HANISH, U.K., FELGNER, P.L., and RESZKA, R. (1996). A continuous intracerebral gene delivery system for in vivo liposome-mediated gene therapy. Gene Ther. 3, 472-476.
21. ZHU, N., LIGGITT, D., LIU, Y., and DEBS, R. (1993). Systemic gene expression after intravenous DNA delivery into adult mice. Science 261, 209-211.