In vivo expression of neutrophil inhibitory factor via gene transfer prevents lipopolysaccharide-induced lung neutrophil infiltration and injury by a β2 integrin-dependent mechanism

Journal of Clinical Investigation

Volumn 101, Issue 11, 1998, Pages 2427-2437

  Zhou, Ming Yuan ^a   Lo, Siu K ^b   Bergenfeldt, Magnus ^a   Tiruppathi, Chinnaswamy ^a   Jaffe, Ari ^a   Xu, Ning ^a   Malik, Asrar B ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

CD11a; CD11b; CD18; Intercellular adhesion molecules; Liposome mediated gene transfer

Indexed keywords

INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 2; LIPOPOLYSACCHARIDE; NEUTROPHIL INHIBITORY FACTOR;

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL INJURY; CELL INFILTRATION; ENDOTHELIUM CELL; GENE TRANSFER; LEUKOCYTE ADHERENCE; LUNG INJURY; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE SPECIFICITY; VASCULAR ENDOTHELIUM;

EID: 0032103369     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI407     Document Type: Article

References (41)

1. Brigham, K.L., and B. Meyrick. 1986. Endotoxin and lung injury. Am. Rev. Respir. Dis. 133:913-927.
2. Tate, R.M., and J.E. Repine. 1983. Neutrophils and the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 128:552-559.
3. Harlan, J.M. 1987. Neutrophil-mediated vascular injury. Acta Med. Scand. Suppl. 715:123-129.
4. Xie, J., R. Li, P. Kotovuori, C. Vermont-Desroches, J. Wijdense, M.A. Arnaout, P. Nortamo, and C.G. Gahmberg. 1995. Intercellular adhesion molecule-2 (CD102) binds to the leukocyte integrin CD11b/CD18 through the A domain. J. Immunol. 155:3619-3628.
5. Malik, A.B., and S.K. Lo. 1996. Vascular endothelial adhesion molecules and tissue inflammation. Pharmacol. Rev. 48:213-229.
6. Anderson, D.C., and T.A. Springer. 1987. Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins. Ann. Rev. Med. 38:175-194.
7. Arnaout, M.A., S.K. Gupta, M.W. Pierce, and D.G. Tenen. 1988. Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3). J. Cell Biol. 106:2153-2158.
8. Arnaout, M.A. 1990. Structure and function of the leukocyte adhesion molecules CD11/CD18. Blood. 75:1037-1050.
9. Furie, M.B., M.C.A. Tancinco, and C.W. Smith. 1991. Monoclonal antibodies to leukocyte integrins CD11a/CD18 and CD11b/CD18 or intercellular adhesion molecule-1 inhibit chemoattractant-stimulated neutrophil transendothelial migration in vitro. Blood. 78:2089-2097.
10. Graf, J.M., C.W. Smith, and M.M. Mariscalco. 1996. Contribution of LFA-1 and Mac-1 to CD18-dependent neutrophil emigration in a neonatal rabbit model. J. Appl. Physiol. 80:1984-1992.
11. Lu, H., C.W. Smith, J. Perrard, D. Billiard, L. Tang, S.B. Shappell, M.L. Entman, A.L. Beaudet, and C.M. Ballantyne. 1997. LFA is sufficient in mediating neutrophil emigration in Mac-1-deficient mice. J. Clin. Invest. 99:1340-1350.
12. Lee, J.O., P. Rieu, M.A. Arnaout, and R. Liddington. 1995. Crystal structure of the A domain from the alpha-subunit of integrin CR3 (CD11b/ CD18). Cell. 80:631-638.
13. Zhou, L., D.H.S. Lee, J. Plescia, C.Y. Lau, and D.C. Liddington. 1994. Differential ligand binding specificities of recombinant CD11b/CD18 integrin I-domain. J. Biol. Chem. 269:17075-17079.
14. Rothlein, R., M.L. Dustin, S.D. Marlin, and T.A. Springer. 1986. A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J. Immunol. 137:1270-1274.
15. Vedder, N.B., R.K. Winn, C.L. Rice, and J.M. Harlan. 1989. Neutrophil-mediated vascular injury in shock and multiple organ failure. Prog. Clin. Biol. Res. 299:181-191.
16. Morisaki, T., T. Goya, H. Toh, K. Nishihara, and M. Torisu. 1991. The anti Mac-1 monoclonal antibody inhibits neutrophil sequestration in lung and liver in a septic murine model. Clin. Immunol. Immunopathol. 61:365-375.
17. Tang, W.W., E.S. Yi, D.G. Remick, A. Wittwer, S. Yin, M. Qi, and T.R. Ulich. 1995. Intratracheal injection of endotoxin and cytokines. IX. Contribution of CD11a/ICAM-1 to neutrophil emigration. Am. J. Physiol. 269:L653-L659.
18. Kumasaka, T., W.M. Quinlan, N.A. Doyle, T.P. Condon, and C. Doerschuk. 1997. Role of the intercellular adhesion molecule-1 (ICAM-1) in endotoxin-induced pneumonia evaluated using ICAM-1 antisense oligonucleotides. anti-ICAM-1 monoclonal antibodies, and ICAM-1 mutant mice. J. Clin. Invest. 10:2362-2369.
19. Lu, H., B.J. Hughes, J. Smolen, C.M. Ballantyne, L. Tang, A.L. Beaudet, and C.W. Smith. 1997. Role of Mac-1 (CD1b/CD18) in neutrophil functions in vivo. FASEB (Fed. Am. Soc. Exp. Biol.) J. 11:1963a. (Abstr.)
20. Eichacker, P.Q., W.D. Hoffman, A. Farese, R.L. Danner, A.F. Suffredini, Y. Waisman, S.M. Banks, T. Mougins, L. Wilson, R. Rothlein, et al. 1993. Leukocyte CD18 monoclonal antibody worsens endotoxemia and cardiovascular injury in canines with septic shock. J. Appl. Physiol. 74:1885-1892.
21. McCandless, B.K., R.P. Kaufman, Jr., J.A. Cooper, P.H. Neumann, and A.B. Malik. 1994. Mediation of lung neutrophil uptake after endotoxin by CD18-integrin-dependent and -independent mechanisms. Am. J. Physiol. 266: H1451-H1456.
22. Moyle, M., D.L. Foster, D.E. McGrath, S.M. Brown, Y. Laroche, J.D. Meutter, P. Stanssens, C.A. Bogowitz, V.A. Fried, J.A. Ely, et al. 1994. A hookworm glycoprotein that inhibits neutrophil function is a ligand of the integrin CD11b/CD18.J. Biol. Chem. 269:10008-10015.
23. Muchowski, P.J., L. Zhang, E.R. Chang, H.R. Soule, E.F. Plow, and M. Moyle. 1994. Functional interaction between the integrin antagonist neutrophil inhibitory factor and the I domain of CD11b/CD18. J. Biol. Chem. 269:26419-26423.
24. 2 integrin CR3 (CD11b/CD18) is a receptor for the hookworm-derived neutrophil adhesion inhibitor NIF. J. Cell Biol. 127:2081-2091.
25. Barnard, J.W., M.G. Biro, S.K. Lo, S. Ohno, M.A. Carozza, M. Moyle, H.R. Soule, and A.B. Malik. 1995. Neutrophil inhibitory factor prevents neutrophil-dependent lung injury. J. Immunol. 155:4876-4881.
26. Liu, Y., D. Liggitt, W. Zhong, G. Tu, K. Gaensler, and R. Debs. 1995. Cationic liposome-mcdiated intravenous gene delivery. J. Biol. Chem. 270: 24864-24870.
27. Gao, X., and L. Huang. 1995. Cationic liposome mediated gene transfer. Gene Ther. 2:710-722.
28. Ausubel, F.M., R. Brent, R.E. Kingston, D.D. Moore, J.G. Seidman, J.L. Smith, and K. Struhl. 1995. Current Protocols in Molecular Biology. John Wiley and Sons, New York. 975-976.
29. Saltini, C., A.J. Hance, V.J. Ferrans, F. Basset, P.B. Bitterman, and R.G. Crystal. 1984. Accurate quantification of cells recovered by bronchoalveolar lavage. Am. Rev. Respir. Dis. 130:650-658.
30. Krawisz, J.E., P. Sharon, and W.F. Stenson. 1984. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Gastroenterology. 87:1344-1350.
31. Jin, F., C. Nathan, D. Radzioch, and A. Ding. 1997. Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide. Cell. 88:417-426.
32. Lo, S.K., G.A. Van Seventer, S.M. Levin, and S.D. Wright. 1989. Two leukocyte receptors (CD11a/CD18 and CD11b/CD18) mediate transient adhesion to endothelium by binding to different ligands. J. Immunol. 143:3325-3329.
33. Green, T.P., D.E. Johnson, T.P. Marchessault, and C.W. Gatto. 1988. Transvascular flux and tissue accrual of Evans blue: effects of endotoxin and histamine. J. Lab. Clin. Med. 111:173-183.
34. Glauser, M.P., G. Zanetti, J.-D. Baumgartner, and J. Cohen. 1991. Septic shock: pathogenesis. Lancet. 338:732-739.
35. Springer, T.A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 76:301-314.
36. Diamond, M.S., J. Garcia-Aguilar, J.K. Bickford, A.L. Corbi, and T.A. Springer. 1993. The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. J. Cell Biol. 120: 1031-1043.
37. 2 integrin CD11b in mediating experimental lung injury in mice. Am. J. Respir Cell Mol. Biol. 14:363-373.
38. Curiel, D.T., J.M. Pilewski, and S.M. Albelda. 1996. Gene therapy approaches for inherited and acquired lung diseases. Am. J. Respir. Cell Mol. Biol. 14:1-18.
39. Muller, D.W., D. Gordon, H. San, Z. Yang, and E.G. Nabel. 1994. Catheter-mediated pulmonary vascular gene transfer and expression. Circ. Res. 75: 1039-1049.
40. McLean, J.W., E.A. Fox, P. Baluk, P.B. Bolton, A. Haskell, R. Pearlman, G. Thurston, E.Y. Umemoto, and D.M. McDonald. 1997. Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice. Am. J. Physiol. 273:H387-H404.
41. Standiford, T.J., S.L. Kunkel, N.W. Lukacs, M.J. Greenberger, J.M. Danforth, R.G. Kunkel, and R.M. Streiter. 1995. Macrophage inflammatory protein-1 mediates lung leukocyte recruitment, lung capillary leak, and early mortality in murine endotoxemia. J. Immunol. 155:1515-1524.