Characteristics of Drusen and Bruch's membrane in postmortem eyes with age-related macular degeneration

Archives of Ophthalmology

Volumn 115, Issue 2, 1997, Pages 267-273

  Spraul, Christoph W ^a,b   Grossnihlatis, Hans E ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY EYE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; BASEMENT MEMBRANE; BRUCH MEMBRANE; CADAVER; CALCIFICATION; CONTROLLED STUDY; DRUSEN; EXUDATIVE RETINITIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION;

EID: 0031050490     PISSN: 00039950     EISSN: None     Source Type: Journal    
DOI: 10.1001/archopht.1997.01100150269022     Document Type: Article

References (44)

1. Ferris FL, Fine SL, Hymann L. Age-related macular degeneration and blindness due to neovascular maculopathy. Arch Ophthalmol. 1984;102: 1640-1642.
2. Leibowitz H, Krueger DE, Maunder LR. The Framingham eye study monograph: an ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2361 adults, 1973-1975. Surv Ophthalmol. 1980;24(suppl):335-610.
3. Wetzig PC. Treatment of drusen-related aging macular degeneration by photocoagulation. Trans Am Ophthalmol Soc. 1988:86:276-290.
4. Bressler SB, Maguire MG, Bressler NM, Fine SL, the Macular Photocoagulation Study Group. Relationship of drusen and abnormalities of the retinal pigment epithelium to the prognosis of neovascular macular degeneration. Arch Ophthalmol. 1990;108:1442-1447.
5. Bressler NM, Suva JC, Bressler SB, Fine SL, Green WR. Clincopathologic correlation of drusen and retinal pigment epithelial abnormalities in age-related macular degeneration. Retina. 1994;14: 130-142.
6. Bressler NM, Bressler SB, Seddon JM, Gragoudas VS, Jacobson LP. Drusen characteristics in patients with exudative versus non-exudative agerelated macular degeneration. Retina. 1988;8: 109-114.
7. Gregor Z, Bird AC, Chisholm IH. Senile disciform macular degeneration in the second eye. BrJOphthalmol. 1977:61:141-147.
8. Gass JD. Drusen and disciform macular detachment and degeneration. Arch Ophthalmol. 1973; 90:206-217.
9. Sarks JP, Sarks SH, Killingsworth MC. Evolution of soft drusen in age-related macular degeneration. Eye. 1994;8:269-283.
10. Green WR, Enger C. Age-related macular degeneration histopathologic studies. Ophthalmology. 1993:100:1519-1535.
11. Green WR, McDonnell PJ, Yeo JH. Pathologic features of senile macular degeneration. Ophthalmology. 1985:92:615-627.
12. Loftier KU, Lee WR. Basal linear deposit in the human macula. Craefss Arch Clin Exp Ophthalmol. 1986:224:493-501.
13. Green WR. Retina. In: Spencer WH, ed. Ophthalmic Pathology: An Atlas and Textbook. 3rd ed. Philadelphia, Pa: WB Saunders Co; 1985;2: 924-1033.
14. Sarks SH. Ageing and degeneration in the macular region: a clinico-pathological study. Br J Ophthalmol. 1976:60:324-341.
15. van der Schaft TL, Mooy CM, de Bruijn WC, Oron FG, Mulder PGH, de Jong PTVM. Histologie features of the early stages of age-related macular degeneration: a statistical analysis. Ophthalmology. 1992;99:278-286.
16. Klein R, Davis MD, Magli YL, Segal P, Klein BEK, Hubbard L. The Wisconsin age-related maculopathy grading system. Ophthalmology. 1991; 98:1128-1134.
17. Pauleikhoff D. Drusen in der Bruchschen Membran: Ihre Bedeutung für die Pathogenese und Therapie der altersabhängigen Makuladegeneration. Ophthalmologe. 1992:89:363-386.
18. Pauleikhoff D, Barondes MJ, Minassian D, Chrisholm J, Wessing A, Bird AC. Drusen und ihre Bedeutung bei altersabhängigen Makuladegenerationen. Fortschr Ophthalmol. 1990;87: 429-432.
19. Pauleikhoff D, Barondes MJ, Minassian D, Chisholm IH, Bird AC. Drusen as risk factors in agerelated macular disease. Am J Ophthalmol. 1990; 109:38-43.
20. Strahlmann ER, Fine SL, Hillis A. The second eye of patients with senile macular degeneration. Arch Ophthalmol. 1983;101:1191-1193.
21. Smiddy WE, Fine SL. Prognosis of patients with bilateral macular drusen. Ophthalmology. 1984; 91:271-277.
22. Vinding T. Occurrence of drusen, pigmentary changes and exudative changes in the macula with reference to age-related macular degeneration: an epidemiological study of 1000 aged individuals. Acta Ophthalmol Scand. 1990;68:410-414.
23. Sarks SH. Drusen and their relationship to senile macular degeneration. Aust J Ophthalmol. 1980:8:117-130.
24. Sarks SH, Penfold PL, Killingsworth MC. Patterns in macular degeneration. In: Ryan SJ, Dawson AK, Little HL, eds. Retinal Diseases. New York, NY: Grune & Stratton Inc; 1985:87-93.
25. Jampol LM, Acheson R, Eagle RC, Serjeant G, O'Grady R. Calcification of Bruch's membrane in angioid streaks with homozygous sickle cell disease. Arch Ophthalmol. 1987;105:93-98.
26. Davis WL, Jones RG, Hagler HK. An electron microscopic histochemical and analytical x-ray microprobe study of calcification in Bruch's membrane from human eyes. JHistochem Cytochem. 1981:29:601-608.
27. Walker ER, Frederickson RG, Mayes MD. The mineralization of elastic fibers and alterations of extracellular matrix in pseudoxanthoma elasticum. Arch Dermatol. 1989;125:70-76.
28. Auker C, Carpenter DO. Choroidal blood flow as a heat dissipating mechanism in the macula. Am J Ophthalmol. 1980;89:641-646.
29. Algvere PV, Torstensson PA, Tengroth BM. Light transmittance of ocular media in living rabbit eyes. Invest Ophthalmol Vis Sci. 1993:34:349-354.
30. Boettner EA, Wolter JR. Transmission of the ocular media. Invest Ophthalmol Vis Sci. 1962;1: 776-783.
31. van der Schaft TL, Mooy CM, de Bruijn WC, Mulder PG, Pameyer JH, de Jong PTVM. Increased prevalence of disciform macular degeneration after cataract extraction with implantation of an intraocular lens. Br J Ophthalmol. 1994;78:441-445.
32. Lamy F, Baurain R, Quay M. Photolysis of desmo'sine and isodesmosine by ultraviolet light. In: Sandberg LB, Gray WR, Franzblau C, eds. Elastin and Elastic Tissue. New York, NY: Plenum Publishing Corp; 1977:177-187.
33. Finlayson GR, Sams WM, Smith JG. Erythema ab igné: a histopathological study. J Invest Dermatol. 1966:46:104-108.
34. Blumenkranz MS, Russell SR, Robey MG, KottBlumenkranz R, Penneys N. Risk factors in agerelated maculopattiy complicated by choroidal neovascularization. Ophthalmology. 1986:96:552-558.
35. Newsome DA, Huh W, Green WR. Bruch's membrane age-related changes vary by region. Curr Eye Res. 1987:6:1211-1221.
36. Nakaizumi Y, Hogan MJ, Feeney L. The ultrastructure of Bruch's membrane, 111: the macular area of the human eye. Arch Ophthalmol. 1964; 72:395-400.
37. van der Schaft TL, de Bruijn WC, Mooy CM, Ketelaars DA, de Jong PTVM. Is basal laminar deposit unique for age-related macular degeneration? Arch Ophthalmol. 1991:110:420-425.
38. Eagle RC. Mechanisms of maculopathy. Ophthalmology. 1984:91:613-625.
39. Glaser WR, Campochiaro PA, Davis JL Jr, Sato M. Retinal pigment epithelial cells release an inhibitor of neovascularization. Arch Ophthalmol. 1985;103:1870-1875.
40. Miller H, Miller B, Ryan SJ. The role of retinal pigment epithelium in the involution of subretinal neovascularization. Invest Ophthalmol Vis Sci. 1986:27:1644-1652.
41. Körte GE, Bellhorn RW, Burns MS. Remodeling of the retinal pigment epithelium in response to intraepithelial capillaries: evidence that capillaries influence the polarity of epithelium. Cell Tissue Res. 1986:245:135-142.
42. Amin R, Puklin JE, Frank RN. Growth factor localization in choroidal neovascular membranes of age-related macular degeneration. Invest Ophthalmol Vis Sci. 1994:35:3178-3188.
43. Coffey AJH, Brownstein S. The prevalence of macular drusen in postmortem eyes. Am J Ophthalmol. 1986:102:164-174.
44. Lewis H, Straatsma BR, Foos RY. The prevalence of macular drusen in postmortem eyes. Am J Ophthalmol. 1986:102:801-802.