The lipid composition of drusen, Bruch's membrane, and sclera by hot stage polarizing light microscopy

Investigative Ophthalmology and Visual Science

Volumn 42, Issue 7, 2001, Pages 1592-1599

  Haimovici, R ^a   Gantz, D L ^a   Rumelt, S ^a   Freddo, T F ^a   Small, D M ^a  

^a Gundersen Eye Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL ESTER;

ADOLESCENT; ADULT; AGED; AGING; ANISOTROPY; ARTICLE; BIREFRINGENCE; BRUCH MEMBRANE; CLINICAL ARTICLE; CRYSTALLIZATION; DRUSEN; FEMALE; FROZEN SECTION; HISTOCHEMISTRY; HUMAN; LIPID COMPOSITION; MALE; POLARIZATION MICROSCOPY; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SCLERA; THIN LAYER CHROMATOGRAPHY; TISSUE DISTRIBUTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; AZO COMPOUNDS; BRUCH MEMBRANE; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; LIPID METABOLISM; MALE; MICROSCOPY, POLARIZATION; MIDDLE AGED; RETINAL DRUSEN; SCLERA;

EID: 0035018921     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Aging changes in Bruch's membrane
2. Correlation between lipids extracted from Bruch's membrane and age
3. Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane
4. Correlation between biochemical composition and fluorescein binding of deposits in Bruch's membrane
5. Peripapillary chorioretinal atrophy
6. Characterization of peroxidized lipids in Bruch's membrane
7. Protein analysis of human maculae in relation to age-related maculopathy
8. Vitronectin is a constituent of ocular drusen and the vitronectin gene is expressed in human retinal pigment epithelial cells
9. The histochemistry of drusen
10. Characterization of drusen-associated glycoconjugates
11. Human ocular drusen possess novel core domains with a distinct carbohydrate composition
12. Drusen in age-related macular degeneration: Pathogenesis, natural course, and laser photocoagulation-induced regression
13. Changes in Bruch's membrane with age
14. Lipids of human retina, retinal pigment epithelium, and Bruch's membrane/choroid: Comparison of macular and peripheral regions
15. Identification and detection of in situ cellular and regional differences of lipid composition and class in lipid-rich tissue using hot stage polarizing light microscopy
16. Structure of triglyceride-rich lipoproteins: An analysis of core and surface phases
17. The phase behavior of hydrated cholesterol
18. Progression and regression of atherosclerotic lesions
19. Physical chemistry of the lipids of human atherosclerotic lesions: Demonstration of a lesion intermediate between fatty streaks and advanced plaques
20. The storage lipids in Tangier disease: A physical-chemical study
21. Immunohistochemical light and electron microscopy of basal laminar deposit
22. The physical state of lipids of biologic importance: Cholesterol esters, cholesterol, triglyceride
23. The Alabama age-related macular degeneration grading system for donor eyes
24. Cholesterol accumulates with age in human Bruch's membrane
25. Lipids in human Bruch's membrane: Histochemistry and ultrastructure
26. Altered composition of cerebral microvessel membrane phosphoglycerides from senescent mouse
27. The effect of age on lipid composition and order of rat cerebral microvessels
28. An international classification and grading system for age-related maculopathy and age-related macular degeneration
29. Degenerative and related disorders of the retina and choroid
30. Location substructure and composition of basal laminar drusen compared with drusen associated with aging and age-related macular degeneration
31. The eye
32. Human ocular lipids: Their analysis and distribution
33. Lipids in tissues of the eye. VI: Sphingomyelins and cholesterol esters in human sclera
34. Molecular motions and thermotropic phase behavior of cholesteryl esters with triolein
35. Cholesterol distribution in the bulk tissues of man: Variation with age
36. Lipid in the aortic intima: The correlation of morphologic and chemical characteristics
37. The lipids of grossly normal human aortic intima from birth to old age
38. The influence of age and atherosclerosis on the chemistry of the aortic intima
39. Physical chemistry of the lipids of human atherosclerotic lesions: Demonstration of a lesion intermediate between fatty streaks and advanced plaques
40. The protein and lipid composition of arterial elastin and its relationship to lipid accumulation in the atherosclerotic plaque
41. The role of arterial elastin in the lipid accumulation in human atherosclerotic arteries
42. Development of the atherosclerotic core region. Chemical and ultrastructural analysis of microdissected atherosclerotic lesions from human aorta
43. Synthesis of docosahexanoic acid by retina and retinal pigment epithelium
44. Lipidmetabolismus im retinalen Pigmetepithel (RPE)
45. Apolipoproteins and lipid localization in eyes with age-related macular degeneration (AMD)