메뉴 건너뛰기




Volumn 15, Issue 24, 1996, Pages 6991-7001

Baxα perturbs T cell development and affects cell cycle entry of T cells

Author keywords

Apoptosis; Bax ; Bcl 2; Cell cycle; T cell selection

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2; PROTEIN BAX; PROTEIN BCL 2; REGULATOR PROTEIN;

EID: 0030449990     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb01091.x     Document Type: Article
Times cited : (155)

References (56)
  • 1
    • 0023934235 scopus 로고
    • Human tumour cell kinetics using a monoclonal antibody against iododeoxyuridine: Intratumour sampling variation
    • Begg,A.C., Moonen,L., Hofland,I., Dessing,M. and Bartelink,H. (1988) Human tumour cell kinetics using a monoclonal antibody against iododeoxyuridine: intratumour sampling variation. Radiother. Oncol., 11, 337-347.
    • (1988) Radiother. Oncol. , vol.11 , pp. 337-347
    • Begg, A.C.1    Moonen, L.2    Hofland, I.3    Dessing, M.4    Bartelink, H.5
  • 4
    • 0026721377 scopus 로고
    • Exclusion and inclusion of alpha and beta T cell receptor alleles
    • Borgulya,P., Kishi,H., Uematsu,Y. and von Boehmer,H. (1992) Exclusion and inclusion of alpha and beta T cell receptor alleles. Cell, 69, 529-537.
    • (1992) Cell , vol.69 , pp. 529-537
    • Borgulya, P.1    Kishi, H.2    Uematsu, Y.3    Von Boehmer, H.4
  • 5
    • 0029669929 scopus 로고    scopus 로고
    • T cells from baxα. transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53
    • Brady,H.J.M, Salomons,G.S., Bobeldijk,R.C. and Berns,A.J.M. (1996) T cells from baxα. transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53. EMBO J., 15, 1221-1223.
    • (1996) EMBO J. , vol.15 , pp. 1221-1223
    • Brady, H.J.M.1    Salomons, G.S.2    Bobeldijk, R.C.3    Berns, A.J.M.4
  • 6
    • 0029046693 scopus 로고
    • Expression of Bcl-2, Bcl-x and Bax after T cell activation and IL-2 withdrawal
    • Broome,H.E., Dargan,C.M., Krajewski,S. and Reed,J.C. (1995) Expression of Bcl-2, Bcl-x and Bax after T cell activation and IL-2 withdrawal. J. Immunol., 155, 2311-2317.
    • (1995) J. Immunol. , vol.155 , pp. 2311-2317
    • Broome, H.E.1    Dargan, C.M.2    Krajewski, S.3    Reed, J.C.4
  • 7
    • 0028807837 scopus 로고
    • A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection
    • Calnan,B.J., Szychowski,S., Chan,F.K.-M., Cado,D. and Winoto,A. (1995) A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection. Immunity, 3, 273-282.
    • (1995) Immunity , vol.3 , pp. 273-282
    • Calnan, B.J.1    Szychowski, S.2    Chan, F.K.-M.3    Cado, D.4    Winoto, A.5
  • 9
    • 0021367846 scopus 로고
    • Glucoconicoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death
    • Cohen,J.J. and Duke,R.C. (1984) Glucoconicoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J. Immunol., 132, 38-42.
    • (1984) J. Immunol. , vol.132 , pp. 38-42
    • Cohen, J.J.1    Duke, R.C.2
  • 11
    • 0029315510 scopus 로고
    • Tumour suppressors, kinases and clamps: How p53 regulates the cell cycle in response to DNA damage
    • Cox,L.S. and Lane,D.P. (1995) Tumour suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage. BioEssays, 17, 501-508.
    • (1995) BioEssays , vol.17 , pp. 501-508
    • Cox, L.S.1    Lane, D.P.2
  • 12
    • 0025325169 scopus 로고
    • T cell receptor gene diversity and selection
    • Davis,M.M. (1990) T cell receptor gene diversity and selection. Annu. Rev. Biochem., 59, 475-496.
    • (1990) Annu. Rev. Biochem. , vol.59 , pp. 475-496
    • Davis, M.M.1
  • 13
  • 14
    • 0029022365 scopus 로고
    • Involvement of an ICE-like protease in Fas-mediated apoptosis
    • Enari,M., Hug,H. and Nagata,S. (1995) Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature, 375, 78-81.
    • (1995) Nature , vol.375 , pp. 78-81
    • Enari, M.1    Hug, H.2    Nagata, S.3
  • 15
    • 0028229732 scopus 로고
    • Inactivation of a cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes
    • Firpo,E.J., Koff,A., Solomon,M.J. and Roberts,J.M. (1994) Inactivation of a cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes. Mol. Cell. Biol., 14, 4889-4901.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4889-4901
    • Firpo, E.J.1    Koff, A.2    Solomon, M.J.3    Roberts, J.M.4
  • 17
    • 0025035509 scopus 로고
    • T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages
    • Guidos,C.J., Danska,J.S., Fathman,C.G. and Weissman,I.L. (1990) T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages. J. Exp. Med., 172, 835-845.
    • (1990) J. Exp. Med. , vol.172 , pp. 835-845
    • Guidos, C.J.1    Danska, J.S.2    Fathman, C.G.3    Weissman, I.L.4
  • 18
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper,J.W., Adami,G.R., Wei,N., Keyomarsi,K. and Elledge,S.J. (1993) The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 75, 805-816.
    • (1993) Cell. , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 19
    • 0028288277 scopus 로고
    • C.elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
    • Hengartner,M.O. and Horvitz,H.R. (1994) C.elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell. 76, 665-676.
    • (1994) Cell. , vol.76 , pp. 665-676
    • Hengartner, M.O.1    Horvitz, H.R.2
  • 20
    • 0025933951 scopus 로고
    • Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice
    • Huesmann,M., Scott,B., Kisielow,P and von Boehmer,H. (1991) Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice. Cell, 9, 533-540.
    • (1991) Cell , vol.9 , pp. 533-540
    • Huesmann, M.1    Scott, B.2    Kisielow, P.3    Von Boehmer, H.4
  • 21
    • 0029966057 scopus 로고    scopus 로고
    • Essential flexibility in the T-cell recognition of antigen
    • Kersh,G.J. and Allen,P.M. (1996) Essential flexibility in the T-cell recognition of antigen. Nature, 380, 495-498.
    • (1996) Nature , vol.380 , pp. 495-498
    • Kersh, G.J.1    Allen, P.M.2
  • 22
    • 0029011805 scopus 로고
    • Cell cycle and apoptosis: Common pathways to life and death
    • King,K.L. and Cidlowski,J.A. (1995) Cell cycle and apoptosis: common pathways to life and death. J. Cell. Biochem., 58, 175-180.
    • (1995) J. Cell. Biochem. , vol.58 , pp. 175-180
    • King, K.L.1    Cidlowski, J.A.2
  • 23
    • 0028359368 scopus 로고
    • Thymic selection of CD8 single positive cells with a class II major histocompatibility complex-restricted receptor
    • Kirberg,J., Baron,A., Jakob,S., Rolink,A., Karjalainen,K. and von Boehmer,H. (1994) Thymic selection of CD8 single positive cells with a class II major histocompatibility complex-restricted receptor. J. Exp. Med., 180, 25-34.
    • (1994) J. Exp. Med. , vol.180 , pp. 25-34
    • Kirberg, J.1    Baron, A.2    Jakob, S.3    Rolink, A.4    Karjalainen, K.5    Von Boehmer, H.6
  • 24
    • 0029671112 scopus 로고    scopus 로고
    • γ-Radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo
    • Kitada,S., Krajewski,S., Miyashita,T., Krajewska,M. and Reed,J.C. (1996) γ-Radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo. Oncogens, 12, 187-192.
    • (1996) Oncogens , vol.12 , pp. 187-192
    • Kitada, S.1    Krajewski, S.2    Miyashita, T.3    Krajewska, M.4    Reed, J.C.5
  • 27
    • 0029005805 scopus 로고
    • Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis
    • Los,M. et al. (1995) Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature, 375, 81-83.
    • (1995) Nature , vol.375 , pp. 81-83
    • Los, M.1
  • 29
    • 0024521441 scopus 로고
    • bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation
    • McDonnell,T.J., Deane,N., Platt,F.M., Núñez,G., Jaeger,U., McKearn,J.P. and Korsmeyer,S.J. (1989) bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell, 57, 79-88.
    • (1989) Cell , vol.57 , pp. 79-88
    • McDonnell, T.J.1    Deane, N.2    Platt, F.M.3    Núñez, G.4    Jaeger, U.5    McKearn, J.P.6    Korsmeyer, S.J.7
  • 32
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita,T. and Reed,J.C. (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell. 80, 293-299.
    • (1995) Cell. , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 34
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan,D.O. (1995) Principles of CDK regulation. Nature, 374, 131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 35
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicolelti,I., Migliorati,G., Pagliacci,M.C., Grignani,F. and Riccardi,C. (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods, 139, 271-279.
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicolelti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 38
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai,Z., Milliman,C. and Korsmeyer,S.J. (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell, 74, 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.1    Milliman, C.2    Korsmeyer, S.J.3
  • 40
    • 0023612470 scopus 로고
    • Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes
    • Sellins,K.S. and Cohen,J.J. (1987) Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes. J. Immunol., 139, 3199-3206.
    • (1987) J. Immunol. , vol.139 , pp. 3199-3206
    • Sellins, K.S.1    Cohen, J.J.2
  • 41
    • 0025751550 scopus 로고
    • Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • Sentman,C.L., Shutter,J.R., Hockenbery,D., Kanagama,O. and Korsmeyer,S.J. (1991) Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell, 67, 879-888.
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagama, O.4    Korsmeyer, S.J.5
  • 42
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
    • Shan,B. and Lee,W.-H. (1994) Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cel. Biol., 14, 8166-8173.
    • (1994) Mol. Cel. Biol. , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.-H.2
  • 43
    • 0028353492 scopus 로고
    • The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation and death
    • Smith,C.A., Farrah,T. and Goodwin,R.G. (1994) The TNF receptor superfamily of cellular and viral proteins: activation, costimulation and death. Cell, 76, 959-962.
    • (1994) Cell , vol.76 , pp. 959-962
    • Smith, C.A.1    Farrah, T.2    Goodwin, R.G.3
  • 44
    • 0029048498 scopus 로고
    • Life and death during lymphocyte development and function: Evidence for two distinct killing mechanisms
    • Strasser,A. (1995) Life and death during lymphocyte development and function: evidence for two distinct killing mechanisms. Curr. Biol., 7, 228-234.
    • (1995) Curr. Biol. , vol.7 , pp. 228-234
    • Strasser, A.1
  • 45
    • 0025786164 scopus 로고
    • Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
    • Strasser,A., Harris,A.W. and Cory,S. (1991) Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell, 67, 889-899.
    • (1991) Cell , vol.67 , pp. 889-899
    • Strasser, A.1    Harris, A.W.2    Cory, S.3
  • 46
    • 0028117306 scopus 로고
    • Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene
    • Strasser,A., Harris,A.W., von Boehmer,H. and Cory,S. (1994) Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene. Proc. Natl Acad. Sci. USA. 91, 1376-1380.
    • (1994) Proc. Natl Acad. Sci. USA. , vol.91 , pp. 1376-1380
    • Strasser, A.1    Harris, A.W.2    Von Boehmer, H.3    Cory, S.4
  • 47
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser,A., Harris,A.W., Huang,D.C.S., Krammer,P.H. and Cory,S. (1995) Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J., 14, 6136-6147.
    • (1995) EMBO J. , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.S.3    Krammer, P.H.4    Cory, S.5
  • 48
    • 0028054017 scopus 로고
    • T-cell apoptosis detected in situ during positive and negative selection in the thymus
    • Surh,C.D. and Sprent,J. (1994) T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature, 372, 100-103.
    • (1994) Nature , vol.372 , pp. 100-103
    • Surh, C.D.1    Sprent, J.2
  • 52
    • 0028983208 scopus 로고
    • IL-1β converting enzyme (ICE) is not required for apoptosis induced by lymphokine deprivation in an IL-2-dependent cell line
    • Vasilakos,J.P., Ghayur,T., Carroll,R.T., Giegel,D.A., Saunders,J.M., Quintal,L., Keane,M.K. and Shivers,B.D. (1995) IL-1β converting enzyme (ICE) is not required for apoptosis induced by lymphokine deprivation in an IL-2-dependent cell line. J. Immunol., 155, 3433-3442.
    • (1995) J. Immunol. , vol.155 , pp. 3433-3442
    • Vasilakos, J.P.1    Ghayur, T.2    Carroll, R.T.3    Giegel, D.A.4    Saunders, J.M.5    Quintal, L.6    Keane, M.K.7    Shivers, B.D.8
  • 53
    • 0027050145 scopus 로고
    • Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2
    • Vaux,D.L., Weissman,I.L. and Kim,S.K. (1992) Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2. Science, 258, 1955-1957.
    • (1992) Science , vol.258 , pp. 1955-1957
    • Vaux, D.L.1    Weissman, I.L.2    Kim, S.K.3
  • 54
    • 12644257032 scopus 로고
    • Positive selection of lymphocytes
    • von Boehmer,H. (1994) Positive selection of lymphocytes. Cell, 66, 1081-1194.
    • (1994) Cell , vol.66 , pp. 1081-1194
    • Von Boehmer, H.1
  • 55
    • 0030046508 scopus 로고    scopus 로고
    • Life, death and the pursuit of apoptosis
    • White,E. (1996) Life, death and the pursuit of apoptosis. Genes Dev., 10, 1-15.
    • (1996) Genes Dev. , vol.10 , pp. 1-15
    • White, E.1
  • 56
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach,E., Resnitzky,D., Lotem,J., Sachs,L., Kimchi,A. and Oren,M. (1991) Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature, 352, 345-347.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.