Dose-related inversion of cinnarizine and flunarizine effects on mitochondrial permeability transition

European Journal of Pharmacology

Volumn 348, Issue 1, 1998, Pages 115-121

  Elimadi, Aziz ^a   Bouillot, Laurent ^a   Sapena, Rosa ^a   Tillement, Jean Paul ^a   Morin, Didier ^a  

^a FACULTÉ DE MÉDECINE   (France)

Author keywords

Ca2+; Cinnarizine; Flunarizine; Mitochondrial permeability transition; Mitochondrion; Tert butylhydroperoxide

Indexed keywords

BUTYLCRESOL; CALCIUM; CINNARIZINE; CYCLOSPORIN A; FLUNARIZINE; MALONALDEHYDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; DOSE RESPONSE; DRUG BINDING; DRUG POTENCY; LIPID PEROXIDATION; MALE; MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MITOCHONDRION SWELLING; NONHUMAN; OXIDATION; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; CALCIUM; CINNARIZINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUNARIZINE; HISTAMINE H1 ANTAGONISTS; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; MEMBRANE POTENTIALS; MITOCHONDRIA, LIVER; MITOCHONDRIAL SWELLING; NADP; OXIDATION-REDUCTION; OXIDATIVE STRESS; PERMEABILITY; RATS; RATS, WISTAR;

EID: 0032077862     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00135-6     Document Type: Article

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