Antioxidant treatment protects striatal neurons against excitotoxic insults

Neuroscience

Volumn 73, Issue 1, 1996, Pages 185-200

  Nakao, N ^a   Grasbon Frodl, E M ^b   Widner, H ^b   Brundin, P ^b  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b NONE

Author keywords

free radicals; Huntington's disease; lazaroids; quinolinic acid; transneuronal degeneration; phenyl t butyl nitrone

Indexed keywords

2 [[4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]METHYL] 3,4 DIHYDRO 2,5,7,8 TETRAMETHYL 2H 1 BENZOPYRAN 6 OL; APOMORPHINE; CYCLIC AMP; N METHYL DEXTRO ASPARTIC ACID; QUINOLINIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN PROTECTION; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; IMMUNOCYTOCHEMISTRY; LIPID PEROXIDATION; NERVE CELL EXCITABILITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

EID: 0029995487     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(96)00034-6     Document Type: Article

References (75)

1. Auer R. N., Wieloch T., Olsson Y. and Siesjö B. K. (1984) The distribution of hypoglycemic brain damage. Acta Neuropath., Berlin 64, 177-191.
2. Banker G. A. (1980) Trophic interactions between astroglial cells and hippocampal neurons in culture. Science 209, 809-810.
3. Banati R. B., Gehrmann J., Schubert P. and Kreutzberg G. W. (1993) Cytotoxicity of microglia. Glia 7, 111-118.
4. Barbin G., Selak I., Manthorpe M. and Varon S. (1984) Use of central neuronal cultures for the detection of neurotrophic agents. Neuroscience 12, 33-43.
5. Beal M. F., Ferrante R. J., Swartz K. J. and Kowall N. W. (1991) Chronic quinolinic acid lesions in rats closely resemble Huntington's disease. J. Neurosci. 11, 1649-1659.
6. Beal M. F., Kowall N. W., Ellison D. E., Mazurek M. F., Swartz K. J. and Martin J. B. (1986) Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature 321, 168-171.
7. Bernhardt R. and Matus A. (1984) Light and electron microscopic studies of the distribution of microtubule-associated protein 2 in rat brain: a difference between the dendritic and axonal cytoskeletons. J. comp. Neurol. 226, 203-221.
8. Boegman R. J., Smith Y. and Parent A. (1987) Quinolinic acid does not spare striatal neuropeptide Y-immunoreactive neurons. Brain Res. 415, 178-182.
9. Bondy S. C. and Lee D. K. (1993) Oxidative stress induced by glutamate receptor agonists. Brain Res. 610, 229-233.
10. Bottenstein P. and Sato G. H. (1979) Growth of a rat neuroblastoma cell line in serum-free supplement medium. Proc. natn. Acad. Sci. U.S.A. 76, 514-517.
11. Braughler J. M., Hall E. D., Jacobsen E. J., McCall J. M. and Means E. D. (1989) The 21-aminosteroids: potent inhibitors of lipid peroxidation for the treatment of central nervous system trauma and ischemia. Drug Future 14, 143-152.
12. Cao X. and Phillis J. W. (1994) α-Phenyl-tert-butyl-nitrone reduces cortical infarct and edema in rats subjected to focal ischemia. Brain Res. 644, 267-272.
13. Carney J. M., Starke-Reed P. E., Oliver C. N., Landum R. W., Cheng M. S., Wu J. F. and Floyd R. A. (1991) Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-α-phenylnitrone. Proc. natn. Acad. Sci. U.S.A. 88, 3633-3636.
14. Cheng G., Griffin M., Poyer J. L. and McCay P. B. (1993) HPLC procedure for the pharmacokinetics study of the spin-trapping agent, α-phenyl-n-nitrone (PBN). Free Rad. Biol. Med. 8, 93-98.
15. Chesselet M. F., Gonzales C., Lin C. S., Polsky K. and Jin B. K. (1990) Ischemic damage in the striatum of adult gerbils: relative sparing of somatostatinergic and cholinergic interneurons contrast with loss of efferent neurons. Expl Neurol. 110, 209-218.
16. Coyle J. T. and Puttfarcken P. (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262, 689-695.
17. Davies S. W. and Roberts P. J. (1987) No evidence for preservation of somatostatin-containing neurons after intrastriatal injections of quinolinic acid. Nature 327, 326-329.
18. DeCamilli P., Miller P. E., Navone F., Theurkauf W. E. and Vallee R. B. (1984) Distribution of microtubule-associated protein 2 in the nervous system of the rat studies by immunofluorescence. Neuroscience 4, 819-846.
19. DiFiglia M. (1990) Excitotoxic injury of the neostriatum: a model Huntington's disease. Trends Neurosci. 13, 286-289.
20. Dunnett S. B., Isacson O., Sirinathsinghji D. J. S., Clarke D. J. and Björklund A. (1988) Striatal grafts in rats with unilateral neostriatal lesions - III. Recovery from dopamine-dependent motor asymmetry and deficits in skilled paw reaching. Neuroscience 24, 813-820.
21. Eriksson N. P., Persson J. K. E., Svensson M., Arvidsson J., Molander C. and Aldskogius H. (1993) A quantitative analysis of the microglial cell reaction in central primary sensory projection territories following peripheral nerve injury in the adult rat. Expl Brain Res. 96, 19-27.
22. Ferrante R. J., Kowall N. W., Cipolloni P. B., Storey E. and Beal M. F. (1993) Excitotoxin lesions in primates as a model for Huntington's disease: histopathologic and neurochemical characterization. Expl Neurol. 119, 46-71.
23. Ferrante R. J., Kowall N. W. and Richardson E. P. Jr. (1989) Neuronal and neuropil loss in the substantia nigra in Huntington's disease. J. Neuropath. exp. Neurol. 48, 380.
24. Ferrante R. J., Kowall N. W. and Richardson E. P. Jr (1990) Selective loss of immunocytochemical markers in substantia nigra of Huntington's disease. J. Neuropath. exp. Neurol. 49, 345.
25. Francis A. and Pulsinelli W. (1982) The response of GABAergic and cholinergic neurons to transient cerebral ischemia. Brain Res. 243, 271-278.
26. Frodl E. M., Nakao N. and Brundin P. (1994) Lazaroids improve the survival of cultured rat embryonic mesencephalic neurons. NeuroReport 5, 2393-2396.
27. Gehrmann J., Monaco S. and Kreutzberg G. W. (1991) Spinal cord microglial cells and DRG satellite cells rapidly respond to transection of the rat sciatic nerve. Restor. Neurol. Neurosci. 2, 181-198.
28. Gehrmann J., Schoen S. W. and Kreutzberg G. W. (1991) Lesion of the rat entorhinal cortex leads to a rapid microglial reaction in the dentate gyrus. Acta Neuropath. 82, 442-455.
29. Gould T. J. and Bickford P. C. (1994) The effects of chronic treatment with N-tert-butyl-a-phenylnitrone on cerebellar noradrenergic receptor function in aged F344 rats. Brain Res. 660, 333-336.
30. Greenlund L. J. S., Deckwerth T. L. and Johnson E. M. Jr (1995) Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron 14, 303-315.
31. Halpain S., Girault J.-A. and Greengard P. (1990) Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices. Nature 343, 369-372.
32. Hensley K., Aksenova M., Carney J. M., Harris M. and Butterfield D. A. (1995) Amyloid β-peptide spin trapping - I. Peptide enzyme toxicity is related to free radicals spin trap reactivity. NeuroReport 6, 489-492.
33. Hensley K., Aksenova M., Carney J. M., Harris M. and Butterfield D. A. (1995) Amyloid β-peptide spin trapping-II. Evidence for decomposition of the PBN spin adduct. NeuroReport 6, 493-496.
34. Hockenbery D. M., Oltvai Z. N., Yin X.-M., Milliman C. L. and Korsmeyer S. J. (1993) Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75, 241-251.
35. Humburger S. A. and McCay P. B. (1989) Endotoxin-induced mortality in rats is reduced by nitrones. Cir. Shock 29, 329-334.
36. Johnson G. V. W. and Jope R. S. (1992) The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration. J. Neurosci. Res. 33, 505-512.
37. Kessler J. A. (1986) Differential regulation of cholinergic and peptidergic development in the rat striatum in culture. Devl Biol. 113, 77-89.
38. Kitagawa K., Matsumoto M., Niinobe M., Mikoshiba K., Hata R., Ueda H., Handa N., Fukunaga R., Isaka Y., Kimura K. and Kamada T. (1989) Microtubule-associated protein 2 as a sensitive marker for cerebral ischemic damage - immunohistochemical investigation of dendritic damage. Neuroscience 31, 401-411.
39. Krammer E. G. (1980) Anterograde and transsynaptic degeneration "en cascade" in basal ganglia induced by intrastriatal injection of kainic acid: an animal analogue of Huntington's disease. Brain Res. 196, 209-221.
40. Koh J.-Y., Gwag B. J., Lobner D. and Choi D. W. (1995) Potentiated necrosis of cultured cortical neurons by neurotrophins. Science 268, 573-575.
41. Lafon-Cazal M., Pietri S., Culcasi M. and Bockaert J. (1993) NMDA-dependent superoxide production and neurotoxicity. Nature 364, 535-537.
42. Lawson L. J., Perry V. H., Dri P. and Gordon S. (1990) Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 39, 151-170.
43. Mackenzie G. M., Jenner P. and Marsden C. D. (1995) The effect of nitric oxide synthase inhibition on quinolinic acid toxicity in the rat striatum. Neuroscience 67, 357-371.
44. + deregulation, and cytoskeletal pathology. Neurobiol. Aging 16, 187-198.
45. Miyamoto M. and Coyle J. T. (1990) Idebenone attenuates neuronal degeneration induced by intrastriatal injection of excitotoxins. Expl Neurol. 108, 38-45.
46. Monyer M., Goldberg M. F. and Choi D. W. (1989) Glucose deprivation neuronal injury in cortical cell culture. Brain Res. 483, 347-354.
47. Monyer M., Hartley D. M. and Choi D. W. (1990) 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures. Neuron 5, 121-126.
48. Nakao N., Brundin P., Funa K., Lindvall O. and Odin P. (1994) Platelet-derived growth factor exerts trophic effects on rat striatal DARPP-32-containing neurons in culture. Expl Brain Res. 101, 291-296.
49. Nakao N., Frodl E. M., Duan W.-M., Widner H. and Brundin P. (1994) Lazaroids improve the survival of grafted rat embryonic dopamine neurons. Proc. natn. Acad. Sci. U.S.A. 91, 12,408-12,412.
50. Nakao N., Odin P. and Brundin P. (1994) Selective sub-dissection of the striatal primordium for cultures affects the yield of DARPP-32-containing neurons. NeuroReport 5, 1081-1084.
51. Nakao N., Kokaia Z., Odin P. and Lindvall O. (1995) Protective effects of BDNF and NT-3 but not PDGF against hypoglycemic injury to cultured striatal neurons. Expl Neurol. 131, 1-10.
52. Nakao N., Odin P., Lindvall O. and Brundin P. (1996) Differential trophic effects of basic fibroblast growth factor, insulin-like growth factor-1 and neurotrophin-3 on striatal neurons in culture. Expl Neurol. (in press).
53. Norman A. B., Wyatt L. M., Hildebrand J. P., Kolmonpunporn N., Moody C. A., Lehman M. N. and Sanberg P. R. (1990) Sensitization of rotation behavior in rats with unilateral 6-hydroxydopamine or kainic acid-induced striatal lesions. Pharmac. Biochem. Behav. 37, 755-759.
54. Novelli G. P., Angiolini P., Tani R., Consale G. and Bordi L. (1985) Phenyl-t-butyl-a-phenylnitrone is active against traumatic shock in rat. Free Rad. Res. Commun. 1, 321-327.
55. Oliver C. N., Starke-Reed P. E., Stadtman E. R., Liu G. J., Carney J. M. and Floyd R. A. (1990) Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc. natn. Acad. Sci. U.S.A. 87, 5144-5147.
56. Ouimet C. C. and Greengard P. (1990) Distribution of DARPP-32 in the basal ganglia: an electron microscopic study. J. Neurocytol. 19, 39-52.
57. Ouimet C. C., Miller P. E., Hemmings H. C. Jr, Walaas S. I. and Greengard P. (1984) DARPP-32, a dopamine- and adenosine 3′: 5′-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions - III. Immunocytochemical localization. J. Neurosci. 4, 111-124.
58. Oyanagi K., Takeda S., Takahashi H., Ohama E. and Ikuta F. (1989) A quantitative investigation of the substantia nigra in Huntington's disease. Ann. Neurol. 26, 13-19.
59. Paxinos G. and Watson C. (1982) The Rat Brain in Stereotaxic Coordinates. Academic Press, San Diego, CA.
60. Persson J. K. E., Aldeskogius H., Arvidsson J. and Holmberg A. (1991) Ultrastructural changes in the gracile nucleus of the rat after sciatic nerve transection. Anat. Embryol. 184, 591-604.
61. Puttfarcken P. S., Getz R. L. and Coyle J. T. (1993) Kainic acid-induced lipid peroxidation: protection with butylated hydroxytoluene and U78517F in primary cultures of cerebellar granule cells. Brain Res. 624, 223-232.
62. Rush D. K., Lartius R. K., Aschmies S. H. and Uemura E. (1991) Time-dependent effects of intrahippocampal NMDA on the microtubule proteins tau and MAP-2. Soc. Neurosci. Abstr. 17, 1068.
63. Saji M. and Reis D. J. (1987) Delayed transneuronal death of substantia nigra neurons prevented by gamma-aminobutyric acid agonist. Science 235, 66-68.
64. Schulz J. B., Henshaw D. R., Siwek D., Jenkins B. G., Ferrante R. J., Cipolloni P. B., Kowall N. W., Rosen B. R. and Beal M. F. (1995) Involvement of free radicals in excitotoxicity in vivo. J. Neurochem. 64, 2239-2247.
65. Schwarcz R., Fuxe K., Agnati L. F., Hökfelt T. and Coyle J. T. (1979) Rotational behaviour in rats with unilateral striatal kainic acid lesions: a behavioural model for studies on intact dopamine receptors. Brain Res. 170, 485-495.
66. Simian R. and Noszek J. C. (1988) Excitatory amino acids activate calpain I and induce protein breakdown in vivo. Neuron 1, 279-287.
67. Thanos S., Mey J. and Wild M. (1993) Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degeneration and enhances axonal regeneration in vivo and in vitro. J. Neurosci. 13, 455-466.
68. Thomas C. E., Carney J. M., Bernotas R. C., Hay D. A. and Carr A. A. (1994) In vitro and in vivo activity of a novel series of radical trapping agents in model systems of CNS oxidative damage. Ann. N. Y. Acad. Sci. 738, 243-249.
69. Töpper R., Gehrmann J., Schwarz M., Block F., Noth J. and Kreutzberg G. W. (1993) Remote microglial activation in the quinolinic acid model of Huntington's disease. Expl Neurol. 123, 271-283.
70. Uemura Y., Kowall N. W. and Beal M. F. (1990) Selective sparing of NADPH-diaphorase-somatostatin-neuropeptide Y neurons in ischemic gerbil striatum. Ann. Neurol. 27, 620-625.
71. Uhler T. A., David A. M., Frim M., Pakzaban P. and Isacson O. (1994) The effects of megadose methylprednisolone and U-78517F on toxicity mediated by glutamate receptors in the rat neostriatum. Neurosurgery 34, 122-128.
72. Ungerstedt U. and Arbuthnott G. W. (1970) Quantitative recording of rotational behaviour in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system. Brain Res. 24, 485-493.
73. Vincent S. R. and Johansson O. (1983) Striatal neurons containing both somatostatin- and avian pancreatic polypeptide (APP)-like immunoreactivities and NADPH-diaphorase activity: a light and electron microscopic study. J. comp. Neurol. 217, 264-270.
74. Wieloch T. (1985) Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist. Science 230, 681-683.
75. Yue T.-L., Gu J.-L., Lysko P. G., Cheng H.-Y., Barone F. C. and Feuerstein G. (1992) Neuroprotective effects of phenyl-t-butyl-nitrone in gerbil global brain ischemia and in cultured rat cerebellar neurons. Brain Res. 574, 193-197.