Intrastriatal grafts of embryonic mesencephalic rat neurons genetically modified using an adenovirus encoding human Cu/Zn superoxide dismutase

Neuroscience

Volumn 78, Issue 3, 1997, Pages 703-713

  Barkats, M ^a   Nakao, N ^b   Grasbon Frodl, E M ^b   Bilang Bleuel, A ^a   Revah, F ^c   Mallet, J ^a   Brundin, P ^b  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b LUND UNIVERSITY   (Sweden)

^c SANOFI   (France)

Author keywords

adenovirus; ex vivo gene transfer; mesencephalic cells; neural graft; Parkinson's disease; superoxide dismutase

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CIRCLING BEHAVIOR; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; EMBRYO; FEMALE; GENE TRANSFER; IMMUNOCYTOCHEMISTRY; MESENCEPHALON; NERVE TRANSPLANTATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

EID: 0030932056     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(96)00526-X     Document Type: Article

References (50)

1. Abercrombie M. (1946) Estimation of nuclear population from microtome section. Anat. Rec. 94, 239-247.
2. Allan J. E. and Doherty P. C. (1985) Immune T cells can protect or induce fatal neurological disease in murine lymphocytic choriomeningitis. Cell Immunol. 90, 401-407.
3. Barkats M., Bemelmans A.-P., Geoffroy M.-C., Robert J.-J., Horellou P., Revah F. and Mallet J. (1996) An adenovirus encoding CuZnSOD protects cultured striatal neurons against glutamate toxicity. Neuro Report 7, 497-501.
4. Björklund A. (1992) Dopaminergic transplants in experimental Parkinsonism: cellular mechanisms of graft-induced functional recovery. Curr. Opin. Neurobiol. 2, 683-689.
5. Björklund A. and Dunnett S. B. (1980) Reinnervation of the denervated striatum by substantia nigra transplants: functional consequences as revealed by pharmacological and sensorimotor testing. Brain Res. 20, 307-333.
6. Brundin P., Barbin G., Strecker R. E., Isacson O., Prochiantz A. and Björklund A. (1988) Survival and function of dissociated rat dopamine neurones grafted at different developmental stages or after being cultured in vitro. Devl Brain Res. 39, 233-243.
7. Brundin P. and Sauer H. (1991) Grafting human fetal brain tissue: a practical guide. In Intracerebral Transplantation in Movement Disorders (eds Lindvall O., Björklund A. and Widner H.), pp. 171-182. Elsevier, New York.
8. Brundin P., Strecker R. E., Widner H., Clarke D. J., Nilsson O. G., Astedt B., Lindvall O. and Björklund A. (1988) Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: immunological aspects, spontaneous and drug-induced behaviour, and dopamine release. Expl Brain Res. 70, 192-208.
9. Byrnes A. P., Rusby J. E., Wood M. J. A. and Charlton H. M. (1995) Adenovirus gene transfer causes inflammation in the brain. Neuroscience 66, 1015-1024.
10. Dawson V. L. and Dawson T. M. (1996) Free radicals and neuronal cell death. Cell death different. 3, 71-78.
11. Dunnett S. B., Björklund A., Schmidt R. H., Stenevi U. and Iversen S. D. (1983) Intracerebral grafting of neuronal cell suspensions. IV. Behavioural recovery in rats with unilateral 6-OHDA lesions following implantation of nigral cell suspensions in different brain sites. Acta physiol. scand. 522, 29-37.
12. During M. J., Naegele J. R., O'Malley K. L. and Geller A. I. (1994) Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase. Science 266, 1399-1403.
13. Finiels F., Gimenez y Ribotta M., Barkats M., Samolyk M.-L., Robert J.-J., Privat A., Revah F. and Mallet J. (1996) Specific and efficient gene transfer strategy offers new potentialities for the treatment of motor neurone disease. Neuro Report 7, 373-378.
14. Fridovich I. (1995) Superoxide radical and superoxide dismutases. A. Rev. Biochem. 64, 97-112.
15. Frodl E., Duan W.-M., Sauer H., Kupsch A. and Brundin P. (1994) Human embryonic dopamine neurons xenografted to the rat: effects of cryoconservation and varying regional source of donor cells on transplant survival, morphology and function. Brain Res. 647, 286-298.
16. Horellou P., Vigne E., Castel M.-N., Barnéoud P., Colin P., Perricaudet M., Delaère P. and Mallet J. (1994) Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease. Neuro Report 6, 49-53.
17. Kaplitt M. G., Leone P., Samulski R. J., Xiao X., Pfaff D. W., O'Malley K. L. and During M. (1994) Long-term expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nature Genet. 8, 148-153.
18. Lafon-Cazal M., Pietri S., Culcasi M. and Bockaert J. (1993) NMDA-dependent superoxide production and neurotoxicity. Nature 364, 535-537.
19. Le Gal La Salle G., Robert J.-J., Berrard S., Ridoux V., Stratford-Perricaudet L. D., Perricaudet M. and Mallet J. (1993) An adenovirus vector for gene transfer into neurons and glia in the brain. Science 259, 988-990.
20. Lin L.-F. H., Doherty D. H., Lile J. D., Bektesh S. and Collins F. (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260, 1130-1132.
21. Lindvall O. (1994) Neural transplantation in Parkinson's disease. In Functional Neural Transplantation (eds Dunnett S. B. and Björklund A.), pp. 103-137. Raven Press, New York.
22. Mayer E., Fawcett J. W. and Dunnett S. B. (1993) Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons-II. Effects on nigral transplants in vivo. Neuroscience 56, 389-398.
23. Morel F., Doussiere J. and Vignais P. V. (1991) The superoxide-generating oxidase of phagocytic cells. Physiological, molecular and pathological aspects. Eur. J. Biochem. 201, 523-546.
24. Nakao N., Frodl E. M., Duan W.-M., Widner H. and Brundin P. (1994) Lazaroids improve the survival of grafted rat embryonic dopamine neurons. Proc. natn. Acad. Sci. U.S.A. 91, 12408-12412.
25. Nakao N., Frodl E. M., Widner H., Carlson E., Eggerding F. A., Epstein C. J. and Brundin P. (1995) Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease. Nature Med. 1, 226-231.
26. Nikkah G., Olsson M., Eberhard J., Bentlage C., Cunningham M. and Björklund A. (1994) A microtransplantation approach for cell suspension grafting in the rat Parkinson model: a detailed account of the methodology. Neuroscience 63, 57-72.
27. Okoye G. S., Powell E. M. and Geller H. M. (1995) Migration of A7 immortalized astrocytic cells grafted into the adult rat striatum. J. comp. Neurol. 362, 524-534.
28. Olanow C. W. (1992) An introduction to the free radical hypothesis in Parkinson's disease. Ann. Neurol. 32, S2-S9.
29. Olanow C. W., Kordower J. H. and Freeman T. B. (1996) Fetal nigral transplantation as a therapy for Parkinson's disease. Trends Neurosci. 19, 102-109.
30. Pacifici R. E. and Davies K. J. A. (1991) Protein, lipid and DNA repair systems in oxidative stress: the free radical theory of aging revisited. Gerontology 37, 36-180.
31. Palmer T. D., Rosman G. J., Osborne W. R. A. and Miller D. (1991) Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes. Proc. natn. Acad. Sci. U.S.A. 88, 1330-1334.
32. Pollock J. D., Williams D. A., Gifford M. A., Li L. L., Du X., Fisherman J., Orkin S. H., Doerschuk C. M. and Dinauer M. C. (1995) Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production. Nature Genet. 9, 202-209.
33. Ridoux V., Robert J.-J., Zhang X., Perricaudet M., Mallet J. and Le Gal La Salle G. (1994) Adenoviral vectors as functional retrograde neuronal tracers. Brain Res. 648, 171-175.
34. Robinson A. P., White T. M. and Mason D. W. (1986) Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. Immunology 57, 239-247.
35. Rosenberg W. S., Breakefield X. O., De Antonio C. and Isaacson O. (1992) Authentic and artifactual detection of the E. coli lacZ gene product in the rat brain by histochemical methods. Molec. Brain Res. 16, 311-315.
36. Rosenblad C. and Martinez-Serrano A. and Björklund A. (1996) Glial cell-line derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts. Neuroscience. (In press).
37. Roy E., Grégoire F., Tardif P., Bédard J. and Gravel C. (1995) Addition of adenoviral vectors to embryonic ventral mesencephalon cell suspensions used for striatal implantation into 6-OHDA-denervated rats induces detrimental immune responses. Soc. Neurosci. Abstr. 21, 1980.
38. Sabaté O., Horellou P., Vigne E., Colin P., Perricaudet M., Buc-Caron M.-H. and Mallet J. (1995) Transplantation to the rat brain of human neural progenitors that were genetically modified using adenoviruses. Nature Genet. 9, 256-260.
39. Sabel B. A., Vick A. and Hollt V. (1995) Neurotoxic reactions of CNS cells following gene transfer with defective herpes simplex virus (HSV-1) vector. Neuro Report 6, 2447-2449.
40. Sagara J. I., Miura K. and Bannai S. (1993) Maintenance of neuronal glutathione by glial cells. J. Neurochem. 61, 1672-1676.
41. Sauer H. and Brundin P. (1991) Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts. Restor. Neurol. Neurosci. 2, 123-135.
42. Sauer H., Fischer W., Nikkhah G., Wiegand S. J., Brundin P., Lindsay R. and Björklund A. (1993) BDNF enhances function rather than survival of intrastriatal dopamine cell-rich grafts. Brain Res. 626, 37-44.
43. Sauer H., Frodl E. M., Kupsch A., Ten Bruggencate G. and Oertel W. H. (1992) Cryopreservation, survival and function of intrastriatal fetal mesencephalic grafts in a rat model of Parkinson's disease. Expl Brain Res. 90, 54-62.
44. Schmidt R. H., Björklund A., Stenevi U., Dunnett S. B. and Gage F. H. (1983) Intracerebral grafting of neuronal cell suspensions. III. Activity of intrastriatal nigral suspension implants as assessed by measurements of dopamine synthesis and metabolism. Acta physiol. scand. 522, 19-28.
45. Stratford-Perricaudet L. D., Makeh I. and Perricaudet M. (1992) Widespread long-term gene transfer to mouse skeletal muscles and heart. J. clin. Invest. 90, 626-630.
46. Takayama H., Ray J., Raymon H. K., Hogg J., Fisher L. J. and Gage F. H. (1995) Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease. Nature Med. 1, 53-58.
47. Troy C. M., Derossi D., Prochiantz A., Greene L. A. and Shelanski M. L. (1996) Down-regulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway. J. Neurosci. 16, 253-261.
48. Ungerstedt U. and Arbuthnott G. W. (1970) Quantitative recording of rotational behavior in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system. Brain Res. 24, 486-493.
49. Widner H. and Brundin P. (1988) Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis. Brain Res. Rev. 13, 287-324.
50. Yurek D. M., Lu W., Hipkens S. and Wiegand J. (1996) BDNF enhances the functional reinnervation of the striatum by grafted fetal dopamine neurons. Expl Neurol. 137, 105-113.