In acute myeloid leukemia, coexpression of at least two proteins, including P-glycoprotein, the multidrug resistance-related protein, bcl-2, mutant p53, and heat-shock protein 27, is predictive of the response to induction chemotherapy

Experimental Hematology

Volumn 26, Issue 12, 1998, Pages 1111-1117

  Kasimir Bauer, S ^a   Ottinger, H ^a   Meusers, P ^a   Beelen, D W ^a   Brittinger, G ^a   Seeber, S ^a   Scheulen, M E ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Acute myelogenous leukemia; Bcl 2; Drug resistance; HSP27; MRP; P53; Pgp

Indexed keywords

GLYCOPROTEIN P; HEAT SHOCK PROTEIN 27; PROTEIN BCL 2;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ARTICLE; CANCER RESISTANCE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TREATMENT OUTCOME;

ACUTE DISEASE; ADULT; AGED; ANALYSIS OF VARIANCE; ATP-BINDING CASSETTE TRANSPORTERS; DRUG RESISTANCE, MULTIPLE; FEMALE; HEAT-SHOCK PROTEINS; HUMANS; LEUKEMIA, MYELOID; MALE; MIDDLE AGED; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION; NEOPLASM PROTEINS; P-GLYCOPROTEIN; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-BCL-2; REMISSION INDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0031735836     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)