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Volumn 18, Issue 4 C, 1998, Pages 2905-2917

Multidrug resistance and its reversal

Author keywords

Antibodies; Antisense; Chemosensitizer; Clinical trials; Multidrug resistance; Reversal

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; ALBUMIN; ANTISENSE OLIGODEOXYNUCLEOTIDE; BISPECIFIC ANTIBODY; CYCLOSPORIN A; CYTOSTATIC AGENT; DIHYDROFOLATE REDUCTASE; DNA TOPOISOMERASE (ATP HYDROLYSING); GLUTATHIONE TRANSFERASE; GLYCOPROTEIN P; HEAT SHOCK PROTEIN; IMMUNOTOXIN; METALLOTHIONEIN; MONOCLONAL ANTIBODY; RIBOZYME; THYMIDYLATE SYNTHASE; VERAPAMIL;

EID: 0031843013     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (171)

References (166)
  • 2
    • 0023205811 scopus 로고
    • The cell biology of multiple drug resistance
    • Beck WT: The cell biology of multiple drug resistance. Pharmacol 36: 2879-2887, 1987.
    • (1987) Pharmacol , vol.36 , pp. 2879-2887
    • Beck, W.T.1
  • 3
    • 0024246526 scopus 로고
    • The multidrug resistance phenotype
    • Kaye SB: The multidrug resistance phenotype. Br J Cancer 58: 691-694, 1988.
    • (1988) Br J Cancer , vol.58 , pp. 691-694
    • Kaye, S.B.1
  • 5
    • 0030390492 scopus 로고    scopus 로고
    • Resistance mechanisms and their regulation in lung cancer
    • Volm M and Mattern J: Resistance mechanisms and their regulation in lung cancer. Crit Rev Oncogenesis 7: 227-244, 1996.
    • (1996) Crit Rev Oncogenesis , vol.7 , pp. 227-244
    • Volm, M.1    Mattern, J.2
  • 6
    • 0027120232 scopus 로고
    • P-glycoprotein and resistance to anticancer drugs
    • Ling V: P-glycoprotein and resistance to anticancer drugs. Cancer 69: 2603-2609, 1992.
    • (1992) Cancer , vol.69 , pp. 2603-2609
    • Ling, V.1
  • 7
    • 0028189510 scopus 로고
    • Multidrug resistance in the laboratory and clinic
    • Bellamy WT and Dalton WS: Multidrug resistance in the laboratory and clinic. Adv Clin Chem 31: 1-61, 1994.
    • (1994) Adv Clin Chem , vol.31 , pp. 1-61
    • Bellamy, W.T.1    Dalton, W.S.2
  • 8
    • 0023006005 scopus 로고    scopus 로고
    • Isolation and expression of a complementary DNA that confers multidrug resistance
    • Gros P, Ben Neriah YB, Croop JM and Housman DE: Isolation and expression of a complementary DNA that confers multidrug resistance. Nature 323: 728-731, 1996.
    • (1996) Nature , vol.323 , pp. 728-731
    • Gros, P.1    Ben Neriah, Y.B.2    Croop, J.M.3    Housman, D.E.4
  • 9
    • 0013508682 scopus 로고
    • A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MCDK cells
    • Pastan I, Gottesman MM, Ueda K, Lovelace E, Rutherford AV and Willingham MC: A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MCDK cells. Proc Natl Acad Sci USA 85: 4486-4490, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4486-4490
    • Pastan, I.1    Gottesman, M.M.2    Ueda, K.3    Lovelace, E.4    Rutherford, A.V.5    Willingham, M.C.6
  • 10
    • 0028285002 scopus 로고
    • Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates
    • Stein WD, Cardarelli CO, Pastan I and Gottesman MM: Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates. Mol Pharmacol 45: 763-772, 1994.
    • (1994) Mol Pharmacol , vol.45 , pp. 763-772
    • Stein, W.D.1    Cardarelli, C.O.2    Pastan, I.3    Gottesman, M.M.4
  • 11
    • 0026536805 scopus 로고
    • Volume-regulated chloride channels associated with the human multidrug resistance P-glycoprotein
    • Valverde MA, Diaz M, Sepulveda FV, Gill DR, Hyde SC and Higgins CF: Volume-regulated chloride channels associated with the human multidrug resistance P-glycoprotein. Nature 355: 830-833, 1992.
    • (1992) Nature , vol.355 , pp. 830-833
    • Valverde, M.A.1    Diaz, M.2    Sepulveda, F.V.3    Gill, D.R.4    Hyde, S.C.5    Higgins, C.F.6
  • 14
    • 0028268620 scopus 로고
    • Expression complementary DNA library transfer establishes mrp as a multidrug resistance gene
    • Kruh GD, Chan A, Myers K, Gaughan K, Miki T and Aaronson SA: Expression complementary DNA library transfer establishes mrp as a multidrug resistance gene. Cancer Res 54: 1649-1652, 1994.
    • (1994) Cancer Res , vol.54 , pp. 1649-1652
    • Kruh, G.D.1    Chan, A.2    Myers, K.3    Gaughan, K.4    Miki, T.5    Aaronson, S.A.6
  • 16
    • 0028001416 scopus 로고
    • ATP-dependent transport of glutathione S-conjugates by the multidrug resistance associated protein
    • Jedlitschky G, Leier I, Buchholz U, Center M and Kepler D: ATP-dependent transport of glutathione S-conjugates by the multidrug resistance associated protein. Cancer Res 54: 4833-4836, 1994.
    • (1994) Cancer Res , vol.54 , pp. 4833-4836
    • Jedlitschky, G.1    Leier, I.2    Buchholz, U.3    Center, M.4    Kepler, D.5
  • 22
    • 0031442337 scopus 로고    scopus 로고
    • Expression of lung resistance protein (LRP) in non-small cell lung carcinomas of smokers and non-smokers and its predictive value for doxorubicin resistance
    • Volm M ,Mattern J and Koomägi R: Expression of lung resistance protein (LRP) in non-small cell lung carcinomas of smokers and non-smokers and its predictive value for doxorubicin resistance. Anti-Cancer Drugs 8: 931-936, 1997.
    • (1997) Anti-Cancer Drugs , vol.8 , pp. 931-936
    • Volm, M.1    Mattern, J.2    Koomägi, R.3
  • 24
    • 0025939987 scopus 로고
    • Non-P-glycoprotein-mediated multidrug-resistance in a small cell lung cancer cell line: Evidence for decreased susceptibility to drug-induced DNA damage and reduced levels of topoisomerase II
    • Cole SP, Chandra ER, Dicke FP, Gerlach JH and Mirski EL: Non-P-glycoprotein-mediated multidrug-resistance in a small cell lung cancer cell line: Evidence for decreased susceptibility to drug-induced DNA damage and reduced levels of topoisomerase II. Cancer Res 51: 3345-3352, 1991.
    • (1991) Cancer Res , vol.51 , pp. 3345-3352
    • Cole, S.P.1    Chandra, E.R.2    Dicke, F.P.3    Gerlach, J.H.4    Mirski, E.L.5
  • 26
    • 0003164090 scopus 로고
    • Glutathione S-transferase and anticancer drug resistance
    • Wolley PV and Tew KD (eds), New York, Academic Press
    • Tew KD and Klapper ML: Glutathione S-transferase and anticancer drug resistance. In: Mechanisms of drug resistance in neoplastic cells. Wolley PV and Tew KD (eds), New York, Academic Press, pp 141-159, 1988
    • (1988) Mechanisms of Drug Resistance in Neoplastic Cells , pp. 141-159
    • Tew, K.D.1    Klapper, M.L.2
  • 27
    • 0026622878 scopus 로고
    • Relationship of inherent resistance to doxorubicin, proliferative activity and expression of P-glycoprotein 170, and glutathione S-transferase-π in human lung tumors
    • Volm M, Mattern J and Samsel B: Relationship of inherent resistance to doxorubicin, proliferative activity and expression of P-glycoprotein 170, and glutathione S-transferase-π in human lung tumors. Cancer 70: 764-769, 1992.
    • (1992) Cancer , vol.70 , pp. 764-769
    • Volm, M.1    Mattern, J.2    Samsel, B.3
  • 28
    • 0027224083 scopus 로고
    • Detection of multiple mechanisms in untreated human lung cancer
    • Volm M and Mattern J: Detection of multiple mechanisms in untreated human lung cancer. Onkologie 16: 189-194, 1993.
    • (1993) Onkologie , vol.16 , pp. 189-194
    • Volm, M.1    Mattern, J.2
  • 29
    • 0028037034 scopus 로고
    • Parallel assessment of glutathione-based detoxifying enzymes, O6-alkylguanine-DNA alkyltransferase and P-glycoprotein as indicators of drug resistance in tumor and normal lung of patients with lung cancer
    • Oberli-Schrämmli AE, Joncourt F, Stadler M, Altermatt HJ, Buser K, Ris HB, Schmid U and Cerny T: Parallel assessment of glutathione-based detoxifying enzymes, O6-alkylguanine-DNA alkyltransferase and P-glycoprotein as indicators of drug resistance in tumor and normal lung of patients with lung cancer. Int J Cancer 59: 629-636, 1994.
    • (1994) Int J Cancer , vol.59 , pp. 629-636
    • Oberli-Schrämmli, A.E.1    Joncourt, F.2    Stadler, M.3    Altermatt, H.J.4    Buser, K.5    Ris, H.B.6    Schmid, U.7    Cerny, T.8
  • 30
    • 0025772679 scopus 로고
    • Overexpression of P-glycoprotein and glutathione S-transferase-π in resistant non-small cell lung carcinomas of smokers
    • Volm M, Mattern J and Samsel B: Overexpression of P-glycoprotein and glutathione S-transferase-π in resistant non-small cell lung carcinomas of smokers. Br J Cancer 64: 700-704, 1991.
    • (1991) Br J Cancer , vol.64 , pp. 700-704
    • Volm, M.1    Mattern, J.2    Samsel, B.3
  • 31
    • 0023718397 scopus 로고
    • Fos-associated cellular p39 is related to nuclear transcription factor AP-1
    • Sassone-Corsi P, Lamph HW, Kamps M and Verma IM: Fos-associated cellular p39 is related to nuclear transcription factor AP-1. Cell 54: 553-563, 1988.
    • (1988) Cell , vol.54 , pp. 553-563
    • Sassone-Corsi, P.1    Lamph, H.W.2    Kamps, M.3    Verma, I.M.4
  • 32
    • 0025720735 scopus 로고
    • The role of jun, fos and the AP-1 complex in cell proliferation and transformation
    • Angel P and Karin M: The role of jun, fos and the AP-1 complex in cell proliferation and transformation. Biochim Biophys Acta 1072: 129-157, 1991.
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 33
    • 0026213268 scopus 로고
    • Analysis of the Chinese hamster P-glycoprotein/multidrug resistance gene pgp1 reveals that the AP-1 site is essential for full promoter activity
    • Teeter LD, Eckersberg T, Tsai Y and Kuo MT: Analysis of the Chinese hamster P-glycoprotein/multidrug resistance gene pgp1 reveals that the AP-1 site is essential for full promoter activity. Cell Growth Diff 2: 429-437, 1991.
    • (1991) Cell Growth Diff , vol.2 , pp. 429-437
    • Teeter, L.D.1    Eckersberg, T.2    Tsai, Y.3    Kuo, M.T.4
  • 36
    • 0029074342 scopus 로고
    • Associated expression of protein kinase C with resistance to doxorubicin in human lung cancer
    • Volm M and Pommerenke EW: Associated expression of protein kinase C with resistance to doxorubicin in human lung cancer. Anticancer Res 15: 463-466, 1995.
    • (1995) Anticancer Res , vol.15 , pp. 463-466
    • Volm, M.1    Pommerenke, E.W.2
  • 37
    • 0025318529 scopus 로고
    • Protein kinase C phosphorylates P-glycoprotein in multidrug resistant human KB carcinoma cells
    • Chambers TC, M Avoy EM, Jakobs JW and Eilon G: Protein kinase C phosphorylates P-glycoprotein in multidrug resistant human KB carcinoma cells. J Biol Chem 265: 7679-7686, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 7679-7686
    • Chambers, T.C.1    M Avoy, E.M.2    Jakobs, J.W.3    Eilon, G.4
  • 38
    • 0005165123 scopus 로고
    • Protein kinase C phosphorylates topoisomerase II.Topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells
    • Sahyoun N, Wolf M, Besterman J, Hsiele TS, Sander M, Le Vine III H, Chang KJ and Cuatrecasas E: Protein kinase C phosphorylates topoisomerase II.Topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells. Proc Natl Acad Sci USA 83: 1603-1607, 1986.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 1603-1607
    • Sahyoun, N.1    Wolf, M.2    Besterman, J.3    Hsiele, T.S.4    Sander, M.5    Le Vine III, H.6    Chang, K.J.7    Cuatrecasas, E.8
  • 39
    • 0024401424 scopus 로고
    • Glutathione S-transferase is an in vitro substrate of Ca++-phospholipid-dependent protein kinase (protein kinase C)
    • Tanaguchi H and Pyerin W: Glutathione S-transferase is an in vitro substrate of Ca++-phospholipid-dependent protein kinase (protein kinase C). Biochim Biophys Res Commun 162: 903-907, 1989.
    • (1989) Biochim Biophys Res Commun , vol.162 , pp. 903-907
    • Tanaguchi, H.1    Pyerin, W.2
  • 40
    • 0019430432 scopus 로고
    • Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil
    • Tsuruo T, Iida H, Tsukagoshi S and Sakurai Y: Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil. Cancer Res 41: 1967-1972, 1981.
    • (1981) Cancer Res , vol.41 , pp. 1967-1972
    • Tsuruo, T.1    Iida, H.2    Tsukagoshi, S.3    Sakurai, Y.4
  • 41
    • 0020426820 scopus 로고
    • Increased accumulation of vincristine and adriamycin in drug resistance tumor cells following incubation with calcium antagonists and calmodulin inhibitors
    • Tsuruo T, Iida H, Tsukagoshi S and Sakurai Y: Increased accumulation of vincristine and adriamycin in drug resistance tumor cells following incubation with calcium antagonists and calmodulin inhibitors. Cancer Res 42: 4730-4733, 1982.
    • (1982) Cancer Res , vol.42 , pp. 4730-4733
    • Tsuruo, T.1    Iida, H.2    Tsukagoshi, S.3    Sakurai, Y.4
  • 42
    • 0024421664 scopus 로고
    • Reversal mechanism of multidrug resistance by verapamil. Direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells
    • Yusa K and Tsuruo T: Reversal mechanism of multidrug resistance by verapamil. Direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells. Cancer Res 49: 5002-5006, 1989.
    • (1989) Cancer Res , vol.49 , pp. 5002-5006
    • Yusa, K.1    Tsuruo, T.2
  • 43
    • 0025007511 scopus 로고
    • Pharmacology of drugs that alter multidrug resistance in cancer
    • Ford JM and Hait WN: Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev 42: 155-199, 1990.
    • (1990) Pharmacol Rev , vol.42 , pp. 155-199
    • Ford, J.M.1    Hait, W.N.2
  • 44
    • 0028189510 scopus 로고
    • Multidrug resistance in the laboratory and clinic
    • Bellamy WT and Dalton WS: Multidrug resistance in the laboratory and clinic. Adv Clin Chem 31: 1-61, 1994.
    • (1994) Adv Clin Chem , vol.31 , pp. 1-61
    • Bellamy, W.T.1    Dalton, W.S.2
  • 45
    • 0028935166 scopus 로고
    • Modulators of multidrug resistance. Preclinical studies
    • Ford JM: Modulators of multidrug resistance. Preclinical studies. Hematol Oncol Clin North Am 9: 337-361, 1995.
    • (1995) Hematol Oncol Clin North Am , vol.9 , pp. 337-361
    • Ford, J.M.1
  • 46
    • 0020425220 scopus 로고
    • Verapamil restoration of doxorubicin responsiveness in daunorubicin-resistant Ehrlich ascites carcinoma
    • Slater LM, Murray SL, Wetzel MW, Wisdom RM and DuVall EM: Verapamil restoration of doxorubicin responsiveness in daunorubicin-resistant Ehrlich ascites carcinoma. J Clin Invest 70: 1131-1134, 1982.
    • (1982) J Clin Invest , vol.70 , pp. 1131-1134
    • Slater, L.M.1    Murray, S.L.2    Wetzel, M.W.3    Wisdom, R.M.4    DuVall, E.M.5
  • 47
    • 0021091295 scopus 로고
    • Reversal of acquired resistance to vinca alkaloids and anthracycline antibiotics
    • Tsuruo T: Reversal of acquired resistance to vinca alkaloids and anthracycline antibiotics. Cancer Treat Rep 67: 889-894, 1983.
    • (1983) Cancer Treat Rep , vol.67 , pp. 889-894
    • Tsuruo, T.1
  • 48
    • 0018891417 scopus 로고
    • Circumvention of resistance to daunorubicin by N-acetyldaunorubicin in Ehrlich ascites tumor
    • Skovsgaard T: Circumvention of resistance to daunorubicin by N-acetyldaunorubicin in Ehrlich ascites tumor. Cancer Res 40: 1077-1083, 1880.
    • (1880) Cancer Res , vol.40 , pp. 1077-1083
    • Skovsgaard, T.1
  • 49
    • 0022495689 scopus 로고
    • Cyclosporine A corrects daunorubicin resistance in Ehrlich ascites carcinoma
    • Slater LM, Sweet P, Stupecky M, Wetzel MV and Gupta S: Cyclosporine A corrects daunorubicin resistance in Ehrlich ascites carcinoma. Br J Cancer 54: 235-238, 1986.
    • (1986) Br J Cancer , vol.54 , pp. 235-238
    • Slater, L.M.1    Sweet, P.2    Stupecky, M.3    Wetzel, M.V.4    Gupta, S.5
  • 50
    • 0021180629 scopus 로고
    • Effects of quinidine and related compounds on cytotoxicity and cellular accumulation of vincristine and adriamycin in drug resistant tumor cells
    • Tsuruo H, Iida H, Kitatani Y, Yokota K, Tsukagoshi S and Yakurai Y: Effects of quinidine and related compounds on cytotoxicity and cellular accumulation of vincristine and adriamycin in drug resistant tumor cells. Cancer Res 44: 4303-4307, 1984.
    • (1984) Cancer Res , vol.44 , pp. 4303-4307
    • Tsuruo, H.1    Iida, H.2    Kitatani, Y.3    Yokota, K.4    Tsukagoshi, S.5    Yakurai, Y.6
  • 51
    • 0020465032 scopus 로고
    • In vivo resistance towards anthracyclines, etoposide, and cis-diamine-dichloroplatinum (II)
    • Seeber S, Osieka R, Schmidt CG, Achterrath W and Crooke ST: In vivo resistance towards anthracyclines, etoposide, and cis-diamine-dichloroplatinum (II). Cancer Res 42: 4719-4725, 1982.
    • (1982) Cancer Res , vol.42 , pp. 4719-4725
    • Seeber, S.1    Osieka, R.2    Schmidt, C.G.3    Achterrath, W.4    Crooke, S.T.5
  • 52
    • 0023234519 scopus 로고
    • Certain calcium channel blockers bind specifically to multidrug resistant human KB carcinoma membrane vesicles ar inhibit drug binding to P-glycoprotein
    • Cornwell MM, Pastan I and Gottesman, MM: Certain calcium channel blockers bind specifically to multidrug resistant human KB carcinoma membrane vesicles ar inhibit drug binding to P-glycoprotein. J Biol Chem 262: 2166-2170, 1987.
    • (1987) J Biol Chem , vol.262 , pp. 2166-2170
    • Cornwell, M.M.1    Pastan, I.2    Gottesman, M.M.3
  • 53
    • 0024378411 scopus 로고
    • Photoaffinity labelling of P-glycoprotein in multidrug resistant cells with photoactive analogs of colchicine
    • Safa AR Mehta ND and Agresti M: Photoaffinity labelling of P-glycoprotein in multidrug resistant cells with photoactive analogs of colchicine. Biochem Biophys Res Commun 162: 1402-1408, 1989.
    • (1989) Biochem Biophys Res Commun , vol.162 , pp. 1402-1408
    • Safa, A.R.1    Mehta, N.D.2    Agresti, M.3
  • 54
    • 0024584440 scopus 로고
    • Competive inhibition by verapamil of ATP-dependent light affinity vincristine binding to the plasma membrane of multidrug-resistance K562 cells without calcium ion involvement
    • Naito M and Tsuruo: Competive inhibition by verapamil of ATP-dependent light affinity vincristine binding to the plasma membrane of multidrug-resistance K562 cells without calcium ion involvement. Cancer Res 49: 1452-1455, 1989.
    • (1989) Cancer Res , vol.49 , pp. 1452-1455
    • Naito, M.1    Tsuruo2
  • 55
    • 0025640935 scopus 로고
    • Activity of various amphiphilic agents in reversing multidrug resistance of L1210 cells
    • Pommerenke EW, Osswald H, Hahn EW and Volm M: Activity of various amphiphilic agents in reversing multidrug resistance of L1210 cells. Cancer Letters 55: 17-23, 1990.
    • (1990) Cancer Letters , vol.55 , pp. 17-23
    • Pommerenke, E.W.1    Osswald, H.2    Hahn, E.W.3    Volm, M.4
  • 56
    • 0030177190 scopus 로고    scopus 로고
    • Modulation of chemosensitivity in human colon carcinoma cells by down-regulating protein kinase C-alpha expression
    • Chakrabarty S and Huang S: Modulation of chemosensitivity in human colon carcinoma cells by down-regulating protein kinase C-alpha expression. J Exp Ther Oncol 1: 218-221, 1996.
    • (1996) J Exp Ther Oncol , vol.1 , pp. 218-221
    • Chakrabarty, S.1    Huang, S.2
  • 58
    • 0025878186 scopus 로고
    • In vitro model for intrinsic drug resistance: Effects of protein kinase C activators on the chemosensitivity of cultured human colon cancer cells
    • Dong Z, Ward NE, Fan D, Gupta KP and O'Brian CA: In vitro model for intrinsic drug resistance: Effects of protein kinase C activators on the chemosensitivity of cultured human colon cancer cells. Mol Pharmacol 39: 563-569, 1991.
    • (1991) Mol Pharmacol , vol.39 , pp. 563-569
    • Dong, Z.1    Ward, N.E.2    Fan, D.3    Gupta, K.P.4    O'Brian, C.A.5
  • 59
    • 0022615254 scopus 로고
    • Circumvention of multiple drug resistance in human cancer cells by chloridazine, trifluoperazine and chlorpromazine
    • Akiyama S, Shiraishi N, Kuratomi Y, Nakagawa M and Kuvano M: Circumvention of multiple drug resistance in human cancer cells by chloridazine, trifluoperazine and chlorpromazine. J Natl Cancer Inst 76: 839-844, 1986.
    • (1986) J Natl Cancer Inst , vol.76 , pp. 839-844
    • Akiyama, S.1    Shiraishi, N.2    Kuratomi, Y.3    Nakagawa, M.4    Kuvano, M.5
  • 60
    • 0025565954 scopus 로고
    • Staurosporine, a potent inhibitor of C-kinase, enhances drug accumulation in mutidrug-resistant cells
    • Sato W, Yusa K, Naito M and Tsuruo T: Staurosporine, a potent inhibitor of C-kinase, enhances drug accumulation in mutidrug-resistant cells. Biochem Biophys Res Commun 173: 1252-1257, 1990.
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 1252-1257
    • Sato, W.1    Yusa, K.2    Naito, M.3    Tsuruo, T.4
  • 61
    • 0027397925 scopus 로고
    • Staurosporine reduces P-glycoprotein expression and modulates multidrug resistance
    • Sampson KE, Wolf CL and Abraham I: Staurosporine reduces P-glycoprotein expression and modulates multidrug resistance. Cancer Lett 58: 7-14, 1993.
    • (1993) Cancer Lett , vol.58 , pp. 7-14
    • Sampson, K.E.1    Wolf, C.L.2    Abraham, I.3
  • 62
    • 0028904745 scopus 로고
    • Phosphorylation of the multidrug resistance associated protein gene encoded protein P190
    • Ma L, Krishnamachary N and Center MS: Phosphorylation of the multidrug resistance associated protein gene encoded protein P190. Biochemistry 34: 3338-3343, 1995.
    • (1995) Biochemistry , vol.34 , pp. 3338-3343
    • Ma, L.1    Krishnamachary, N.2    Center, M.S.3
  • 63
    • 0028857378 scopus 로고
    • The specific bisindolylmaleimide PKC-inhibitor GF 109203X efficiently modulates MRP-associated multiple drug resistance
    • Gekeler V, Boer R, Ise W, Sanders KH, Schachtele C and Beck J: The specific bisindolylmaleimide PKC-inhibitor GF 109203X efficiently modulates MRP-associated multiple drug resistance. Biochem Biophys Res Commun 206: 119-126, 1995.
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 119-126
    • Gekeler, V.1    Boer, R.2    Ise, W.3    Sanders, K.H.4    Schachtele, C.5    Beck, J.6
  • 65
    • 0025779565 scopus 로고
    • Circumvention of multidrug resistance in human kidney and kidney carcinoma in vitro
    • Volm M, Pommerenke EW, Efferth T, Löhrke H and Mattern J: Circumvention of multidrug resistance in human kidney and kidney carcinoma in vitro. Cancer 67: 2484-2489, 1981.
    • (1981) Cancer , vol.67 , pp. 2484-2489
    • Volm, M.1    Pommerenke, E.W.2    Efferth, T.3    Löhrke, H.4    Mattern, J.5
  • 66
    • 0026079181 scopus 로고
    • Resistance to doxorubicin in tumor cells in vitro and in vivo after pretreatment with verapamil
    • Donenko FV, Efferth T, Mattern J, Moroz LV and Volm M: Resistance to doxorubicin in tumor cells in vitro and in vivo after pretreatment with verapamil. Chemotherapy 37: 57-61, 1991.
    • (1991) Chemotherapy , vol.37 , pp. 57-61
    • Donenko, F.V.1    Efferth, T.2    Mattern, J.3    Moroz, L.V.4    Volm, M.5
  • 67
    • 15444349233 scopus 로고
    • Verapamil decreases the sensitivity to adriamycin of an adherent small cell lung cancer cell line in vitro
    • Milroy R, Plumb J, Banham SW and Kaye SB: Verapamil decreases the sensitivity to adriamycin of an adherent small cell lung cancer cell line in vitro. Br J Cancer 58: 245, 1988.
    • (1988) Br J Cancer , vol.58 , pp. 245
    • Milroy, R.1    Plumb, J.2    Banham, S.W.3    Kaye, S.B.4
  • 68
    • 0027500507 scopus 로고
    • Increased mdr-1/P-glycoprotein expression after treatment of human colon carcinoma cells with P-glycoprotein antagonists
    • Herzog CE, Tsokos M, Bates SE and Fojo AT: Increased mdr-1/P-glycoprotein expression after treatment of human colon carcinoma cells with P-glycoprotein antagonists. J Biol Chem 268: 2946-2952, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 2946-2952
    • Herzog, C.E.1    Tsokos, M.2    Bates, S.E.3    Fojo, A.T.4
  • 69
    • 0345139075 scopus 로고
    • Functional role of the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies
    • Hamada H and Tsuruo T: Functional role of the 170-to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. Proc Natl Acad Sci USA 83: 7785-7789, 1986.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 7785-7789
    • Hamada, H.1    Tsuruo, T.2
  • 70
    • 0024814693 scopus 로고
    • Inhibition of multidrug-resistant human tumor growth in athymic mice by anti-P-glycoprotein monoclonal antibodies
    • Tsuruo T, Hamada H, Sato S and Heike Y: Inhibition of multidrug-resistant human tumor growth in athymic mice by anti-P-glycoprotein monoclonal antibodies. Jpn J Cancer Res 80: 627-631, 1989.
    • (1989) Jpn J Cancer Res , vol.80 , pp. 627-631
    • Tsuruo, T.1    Hamada, H.2    Sato, S.3    Heike, Y.4
  • 71
    • 0025224853 scopus 로고
    • Monoclonal anti-P-glycoprotein antibody-dependent killing of multidrug-resistant tumor cells by human mononuclear cells
    • Heike Y, Hamada H, Inamura N, Sone S, Ogura T and Tsuruo T: Monoclonal anti-P-glycoprotein antibody-dependent killing of multidrug-resistant tumor cells by human mononuclear cells. Jpn J Cancer Res 81: 1155-1161, 1990.
    • (1990) Jpn J Cancer Res , vol.81 , pp. 1155-1161
    • Heike, Y.1    Hamada, H.2    Inamura, N.3    Sone, S.4    Ogura, T.5    Tsuruo, T.6
  • 72
    • 0025912872 scopus 로고
    • Selective growth inhibition of multidrug-resistant CHO-cells by the monoclonal antibody 265/F4
    • Efferth T, Lathan B and Volm M: Selective growth inhibition of multidrug-resistant CHO-cells by the monoclonal antibody 265/F4. Br J Cancer 64: 87-89, 1991.
    • (1991) Br J Cancer , vol.64 , pp. 87-89
    • Efferth, T.1    Lathan, B.2    Volm, M.3
  • 74
    • 0027166802 scopus 로고
    • Modulation of P-glycoprotein-mediated multidrug resistance by monoclonal antibodies, immunotoxins or antisense oligodeoxynucleotides in kidney carcinoma and normal kidney cells
    • Efferth T and Volm M: Modulation of P-glycoprotein-mediated multidrug resistance by monoclonal antibodies, immunotoxins or antisense oligodeoxynucleotides in kidney carcinoma and normal kidney cells. Oncology 50: 303-308, 1993.
    • (1993) Oncology , vol.50 , pp. 303-308
    • Efferth, T.1    Volm, M.2
  • 76
    • 0027406201 scopus 로고
    • Enhancement of cellular accumulation of cyclosporin A by anti-P-glycoprotein monoclonal antibody MRK16, and synergistic modulation of multidrug resistance
    • Naito M, Tsuge H, Kuroko C, Koyama T, Tomida A, Tatsuda T, Heike Y and Tsuruo T: Enhancement of cellular accumulation of cyclosporin A by anti-P-glycoprotein monoclonal antibody MRK16, and synergistic modulation of multidrug resistance. J Natl Cancer Inst 85: 311-316, 1993.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 311-316
    • Naito, M.1    Tsuge, H.2    Kuroko, C.3    Koyama, T.4    Tomida, A.5    Tatsuda, T.6    Heike, Y.7    Tsuruo, T.8
  • 77
    • 0027167572 scopus 로고
    • Enhancement of reversing effect of cyclosporin A on vincristine resistance by anti P-glycoprotein monoclonal antibody MRK16
    • Naito M, Tsuge H, Kuroko C, Tomida A and Tsuruo T: Enhancement of reversing effect of cyclosporin A on vincristine resistance by anti P-glycoprotein monoclonal antibody MRK16. Jpn J Cancer Res 84: 489-492, 1993.
    • (1993) Jpn J Cancer Res , vol.84 , pp. 489-492
    • Naito, M.1    Tsuge, H.2    Kuroko, C.3    Tomida, A.4    Tsuruo, T.5
  • 78
    • 0022468587 scopus 로고
    • Epidermal growth factor receptor is increased in multidrug-resistant Chinese hamster and mouse tumor cells
    • Meyers MB, Merluzzi VS, Spengler BA and Biedler JL: Epidermal growth factor receptor is increased in multidrug-resistant Chinese hamster and mouse tumor cells. Proc Natl Acad Sci USA 83: 5521-5525, 1986.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5521-5525
    • Meyers, M.B.1    Merluzzi, V.S.2    Spengler, B.A.3    Biedler, J.L.4
  • 80
    • 0027030513 scopus 로고
    • Immunocytochemical detection of oncoproteins in animal and human tumor lines with acquired or inherent multidrug resistance
    • Efferth T and Volm M: Immunocytochemical detection of oncoproteins in animal and human tumor lines with acquired or inherent multidrug resistance. Cancer Detection and Prevention 16: 237-243, 1992.
    • (1992) Cancer Detection and Prevention , vol.16 , pp. 237-243
    • Efferth, T.1    Volm, M.2
  • 81
    • 0027269512 scopus 로고
    • P-glycoprotein associated expression of c-fos and c-jun products in human lung carcinomas
    • Volm M: P-glycoprotein associated expression of c-fos and c-jun products in human lung carcinomas. Anticancer Res 13: 375-378, 1993.
    • (1993) Anticancer Res , vol.13 , pp. 375-378
    • Volm, M.1
  • 82
    • 0027181003 scopus 로고
    • Expression of resistance factors (P-glycoprotein, glutathione S-transferase π and topoisomerase II) and their interrelationship to proto-oncogene products in renal cell carcinoma
    • Volm M, Kästel M, Mattern J and Efferth T: Expression of resistance factors (P-glycoprotein, glutathione S-transferase π and topoisomerase II) and their interrelationship to proto-oncogene products in renal cell carcinoma. Cancer 71: 3981-3987, 1993.
    • (1993) Cancer , vol.71 , pp. 3981-3987
    • Volm, M.1    Kästel, M.2    Mattern, J.3    Efferth, T.4
  • 83
    • 0020933452 scopus 로고
    • Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors
    • Sato JD, Kawamoto T, Le AD, Mendelsohn J, Polikoff J and Sato GH: Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors. Mol Biol Med 1: 511-529, 1983.
    • (1983) Mol Biol Med , vol.1 , pp. 511-529
    • Sato, J.D.1    Kawamoto, T.2    Le, A.D.3    Mendelsohn, J.4    Polikoff, J.5    Sato, G.H.6
  • 84
    • 0026576463 scopus 로고
    • Antibody-directed therapy of multidrug-resistant tumor cells
    • Efferth T and Volm M: Antibody-directed therapy of multidrug-resistant tumor cells. Med Oncol and Tumor Pharmacol 9: 11-19, 1992.
    • (1992) Med Oncol and Tumor Pharmacol , vol.9 , pp. 11-19
    • Efferth, T.1    Volm, M.2
  • 85
    • 0028331276 scopus 로고
    • Resistenzüberwindung bei Tumoren
    • Volm M and Efferth T: Resistenzüberwindung bei Tumoren. Dtsch med Wschr 119: 475-479, 1994.
    • (1994) Dtsch Med Wschr , vol.119 , pp. 475-479
    • Volm, M.1    Efferth, T.2
  • 87
    • 0026721173 scopus 로고
    • Therapeutic applications of oligonucleotides
    • Crooke ST: Therapeutic applications of oligonucleotides. Annu Rev Pharmacol Toxicol 32: 329-376, 1992.
    • (1992) Annu Rev Pharmacol Toxicol , vol.32 , pp. 329-376
    • Crooke, S.T.1
  • 88
    • 0024041180 scopus 로고
    • Role of RNase H in hybrid-arrested translation by antisense oligonucleotides
    • Walder RY and Walder JA: Role of RNase H in hybrid-arrested translation by antisense oligonucleotides. Proc Natl Acad Sci USA 85: 5011-5015, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5011-5015
    • Walder, R.Y.1    Walder, J.A.2
  • 89
    • 0027093252 scopus 로고
    • Down-regulation of c-Myc antigen expression in lymphocytes of Eμ-c-myc transgenic mice treated with anti-c-myc DNA methylphosphonates
    • Wickstrom E, Bacon TA and Wickstrom EL: Down-regulation of c-Myc antigen expression in lymphocytes of Eμ-c-myc transgenic mice treated with anti-c-myc DNA methylphosphonates. Cancer Res 52: 6741-6745, 1992.
    • (1992) Cancer Res , vol.52 , pp. 6741-6745
    • Wickstrom, E.1    Bacon, T.A.2    Wickstrom, E.L.3
  • 90
    • 0024826733 scopus 로고
    • Modulation of drug resistance in a daunorubicin resistant subline with oligonucleoside methylphosphonates
    • Vasanthakumar and Ahmed NK: Modulation of drug resistance in a daunorubicin resistant subline with oligonucleoside methylphosphonates. Cancer Commun 1: 225-232, 1989.
    • (1989) Cancer Commun , vol.1 , pp. 225-232
    • Vasanthakumar1    Ahmed, N.K.2
  • 92
    • 0025167527 scopus 로고
    • Modulation of multidrug resistance by verapamil or mdr1 anti-sense oligodeoxynucleotide does not change the high susceptibility to lymphokine-activated killers in mdr-resistant human carcinoma (LoVo) line
    • Rivoltini L, Colombo MP, Supino R, Ballinari D, Tsuruo T and Parmiani G: Modulation of multidrug resistance by verapamil or mdr1 anti-sense oligodeoxynucleotide does not change the high susceptibility to lymphokine-activated killers in mdr-resistant human carcinoma (LoVo) line. Int J Cancer 46: 727-732, 1990.
    • (1990) Int J Cancer , vol.46 , pp. 727-732
    • Rivoltini, L.1    Colombo, M.P.2    Supino, R.3    Ballinari, D.4    Tsuruo, T.5    Parmiani, G.6
  • 93
    • 0027199910 scopus 로고
    • Overcoming multidrug resistance in human tumor cells using free and liposomally encapsulated antisense oligodeoxynucleotides
    • Thierry AR, Rahman A and Dritschilo A: Overcoming multidrug resistance in human tumor cells using free and liposomally encapsulated antisense oligodeoxynucleotides. Biochem Biophys Res Commun 190: 952-960, 1993.
    • (1993) Biochem Biophys Res Commun , vol.190 , pp. 952-960
    • Thierry, A.R.1    Rahman, A.2    Dritschilo, A.3
  • 94
    • 15444342142 scopus 로고    scopus 로고
    • Modulation of multidrug resistance in human ovarian cancer cell lines by inhibition of P-glycoprotein 170 and PKC-isoenzymes with antisense-oligonucleotides
    • in press
    • Masanek U, Stammler G and Volm M: Modulation of multidrug resistance in human ovarian cancer cell lines by inhibition of P-glycoprotein 170 and PKC-isoenzymes with antisense-oligonucleotides. J Exp and Oncology (in press).
    • J Exp and Oncology
    • Masanek, U.1    Stammler, G.2    Volm, M.3
  • 95
    • 0025878768 scopus 로고
    • The potential use of catalytic RNAs in therapy of HIV infection and other diseases
    • Rossi JJ, Cantin EM, Sarver N and Chang PF: The potential use of catalytic RNAs in therapy of HIV infection and other diseases. Pharmacol Ther 50: 245-254, 1991.
    • (1991) Pharmacol Ther , vol.50 , pp. 245-254
    • Rossi, J.J.1    Cantin, E.M.2    Sarver, N.3    Chang, P.F.4
  • 96
    • 0031973036 scopus 로고    scopus 로고
    • The therapeutic potential of ribozymes
    • James HA and Gibson I: The therapeutic potential of ribozymes. Blood 91: 371-382, 1998.
    • (1998) Blood , vol.91 , pp. 371-382
    • James, H.A.1    Gibson, I.2
  • 97
    • 0027452745 scopus 로고
    • Cleavage of human MDR1 mRNA by a hammerhead ribozyme
    • Kobayashi H, Dorai T, Holland JF and Ohnuma T: Cleavage of human MDR1 mRNA by a hammerhead ribozyme. FEBS Lett 319: 71-74, 1993.
    • (1993) FEBS Lett , vol.319 , pp. 71-74
    • Kobayashi, H.1    Dorai, T.2    Holland, J.F.3    Ohnuma, T.4
  • 98
    • 0028071663 scopus 로고
    • Ribozyme-mediated cleavage of the MDR-1 transcript restores chemosensitivity in previously resistant cancer cells
    • Kiehntopf M, Brach MA, Licht T, Petschauer S, Karawajew L, Kirching C and Hermann F: Ribozyme-mediated cleavage of the MDR-1 transcript restores chemosensitivity in previously resistant cancer cells. EMBO J 13: 4645-4652, 1994.
    • (1994) EMBO J , vol.13 , pp. 4645-4652
    • Kiehntopf, M.1    Brach, M.A.2    Licht, T.3    Petschauer, S.4    Karawajew, L.5    Kirching, C.6    Hermann, F.7
  • 99
    • 0028169597 scopus 로고
    • Reversion of multidrug resistance in the P-glycoprotein-positive human pancreatic cell line [EPP85-181RDB] by introduction of a hammerhead ribozyme
    • Holm PS, Scanlon KJ and Dietel M: Reversion of multidrug resistance in the P-glycoprotein-positive human pancreatic cell line [EPP85-181RDB] by introduction of a hammerhead ribozyme. Br J Cancer 70: 239-243, 1994.
    • (1994) Br J Cancer , vol.70 , pp. 239-243
    • Holm, P.S.1    Scanlon, K.J.2    Dietel, M.3
  • 101
    • 0028110360 scopus 로고
    • Ribozyme-mediated reversal of the multidrug-resistant phenotype
    • Scanlon KJ, Ishida H and Kashani-Sabet M: Ribozyme-mediated reversal of the multidrug-resistant phenotype. Proc Natl Acad Sci USA 91: 11123-11127, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11123-11127
    • Scanlon, K.J.1    Ishida, H.2    Kashani-Sabet, M.3
  • 102
    • 0029042615 scopus 로고
    • Ribozymes as human therapeutic agents
    • Christoffersen RE and Morr JJ: Ribozymes as human therapeutic agents. J Med Chem 38: 2023-2037, 1995.
    • (1995) J Med Chem , vol.38 , pp. 2023-2037
    • Christoffersen, R.E.1    Morr, J.J.2
  • 103
    • 0041536685 scopus 로고
    • Design of compounds having an enhanced tumour uptake, using serum albumin as a carrier. Part I
    • Sinn H, Schrenk HH, Friedrich EA, Schilling U and Maier-Borst W: Design of compounds having an enhanced tumour uptake, using serum albumin as a carrier. Part I. Nucl Med Biol 17: 819-827, 1990.
    • (1990) Nucl Med Biol , vol.17 , pp. 819-827
    • Sinn, H.1    Schrenk, H.H.2    Friedrich, E.A.3    Schilling, U.4    Maier-Borst, W.5
  • 105
    • 0028969022 scopus 로고
    • Circumvention of doxorubicin-resistance in tumours by albumin-conjugated doxorubicin
    • Pommerenke EW, Sinn H and Volm M: Circumvention of doxorubicin-resistance in tumours by albumin-conjugated doxorubicin. Eur J Cancer 31A: 283-284, 1995.
    • (1995) Eur J Cancer , vol.31 A , pp. 283-284
    • Pommerenke, E.W.1    Sinn, H.2    Volm, M.3
  • 110
    • 0025961632 scopus 로고
    • Verapamil with mitoxantrone for advanced ovarian cancer: A negative phase II trial
    • Hendrick AM, Harris AL and Cantwell BMJ: Verapamil with mitoxantrone for advanced ovarian cancer: a negative phase II trial. Ann Oncol 2: 71-72, 1991.
    • (1991) Ann Oncol , vol.2 , pp. 71-72
    • Hendrick, A.M.1    Harris, A.L.2    Cantwell, B.M.J.3
  • 111
    • 0026073181 scopus 로고
    • Doxorubicin in combination with verapamil in advanced colorectal cancer
    • Dalmark M, Pals H and Johnsen AH: Doxorubicin in combination with verapamil in advanced colorectal cancer. Acta Oncol 30: 23-26, 1991.
    • (1991) Acta Oncol , vol.30 , pp. 23-26
    • Dalmark, M.1    Pals, H.2    Johnsen, A.H.3
  • 112
    • 0025739134 scopus 로고
    • A phase II study of epidoxorubicin in colorectal cancer and the use of cyclosporin-A in an attempt to reverse multidrug resistance
    • Verweij J, Herweijer H, Oosterom R, van der Burg ME, Planting AS, Seynaeve C, Stoter G and Noter K: A phase II study of epidoxorubicin in colorectal cancer and the use of cyclosporin-A in an attempt to reverse multidrug resistance. Br J Cancer 64: 361-364, 1991.
    • (1991) Br J Cancer , vol.64 , pp. 361-364
    • Verweij, J.1    Herweijer, H.2    Oosterom, R.3    Van Der Burg, M.E.4    Planting, A.S.5    Seynaeve, C.6    Stoter, G.7    Noter, K.8
  • 113
    • 0025829126 scopus 로고
    • Phase II study of combining vinblastine and cyclosporin A to circumvent multidrug resistance in renal cell cancer
    • Rodenburg CJ, Nooter K, Herweijer H, Seynaeve C, Oosterom R, Stoter G and Verweij J: Phase II study of combining vinblastine and cyclosporin A to circumvent multidrug resistance in renal cell cancer. Ann Oncol 2: 305-306, 1991.
    • (1991) Ann Oncol , vol.2 , pp. 305-306
    • Rodenburg, C.J.1    Nooter, K.2    Herweijer, H.3    Seynaeve, C.4    Oosterom, R.5    Stoter, G.6    Verweij, J.7
  • 119
    • 0029049257 scopus 로고
    • Phase I/II trial of dexverapamil plus vinblastine for patients with advanced renal cell carcinoma
    • Motzer RJ, Lyn P, Fisher P, Lianes P, Ngo RL, Cordon-Cardo C and O'Brian: Phase I/II trial of dexverapamil plus vinblastine for patients with advanced renal cell carcinoma. J Clin Oncol 13: 1958-1965, 1995.
    • (1995) J Clin Oncol , vol.13 , pp. 1958-1965
    • Motzer, R.J.1    Lyn, P.2    Fisher, P.3    Lianes, P.4    Ngo, R.L.5    Cordon-Cardo, C.6    O'Brian7
  • 120
    • 0027375301 scopus 로고
    • A randomised clinical study of verapamil in addition to combination chemotherapy in small cell lung cancer
    • Milroy R: A randomised clinical study of verapamil in addition to combination chemotherapy in small cell lung cancer. Br J Cancer 68: 813-818, 1993.
    • (1993) Br J Cancer , vol.68 , pp. 813-818
    • Milroy, R.1
  • 122
    • 0031963639 scopus 로고    scopus 로고
    • Results of a phase III, double-blind, placebo-controlled trial of megestrol acetate modulation of P-glycoprotein mediated drug resistance in the first-line management of small-cell lung carcinoma
    • Wood L, Palmer M, Hewitt J, Urtasun R, Bruera E, Rapp E and Thaell JF: Results of a phase III, double-blind, placebo-controlled trial of megestrol acetate modulation of P-glycoprotein mediated drug resistance in the first-line management of small-cell lung carcinoma. Br J Cancer 77: 627-631, 1998
    • (1998) Br J Cancer , vol.77 , pp. 627-631
    • Wood, L.1    Palmer, M.2    Hewitt, J.3    Urtasun, R.4    Bruera, E.5    Rapp, E.6    Thaell, J.F.7
  • 123
    • 0026051296 scopus 로고
    • P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil
    • Miller TP, Grogan TM, Dalton WS, Spier CM, Scheper RJ and Salmon SE: P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil. J Clin Oncol 9: 17-24, 1991.
    • (1991) J Clin Oncol , vol.9 , pp. 17-24
    • Miller, T.P.1    Grogan, T.M.2    Dalton, W.S.3    Spier, C.M.4    Scheper, R.J.5    Salmon, S.E.6
  • 129
    • 0024797947 scopus 로고
    • Reciprocal correlation between expression of P-glycoprotein and accumulation of rhodamine 123 in human tumors
    • Efferth T, Löhrke H and Volm M: Reciprocal correlation between expression of P-glycoprotein and accumulation of rhodamine 123 in human tumors. Anticancer Res 9: 1633-1638, 1989.
    • (1989) Anticancer Res , vol.9 , pp. 1633-1638
    • Efferth, T.1    Löhrke, H.2    Volm, M.3
  • 130
    • 0025823086 scopus 로고
    • Time course of MDR gene amplification during in vivo selection for doxorubicin resistance and during reversal in murine leukemia L1210
    • Volm M, Mattern J and Pommerenke EW: Time course of MDR gene amplification during in vivo selection for doxorubicin resistance and during reversal in murine leukemia L1210. Anticancer Res 11: 579-585, 1991.
    • (1991) Anticancer Res , vol.11 , pp. 579-585
    • Volm, M.1    Mattern, J.2    Pommerenke, E.W.3
  • 131
    • 0025836311 scopus 로고
    • Reversing multidrug resistance in L1210 tumor cells by hycanthone or chlorophenoxamine in vitro and in vivo
    • Efferth T, Klett T, Mattern J, Osswald H, Pommerenke EW, Stöhr M and Volm M: Reversing multidrug resistance in L1210 tumor cells by hycanthone or chlorophenoxamine in vitro and in vivo. Anticancer Res 11: 1275-1280, 1991.
    • (1991) Anticancer Res , vol.11 , pp. 1275-1280
    • Efferth, T.1    Klett, T.2    Mattern, J.3    Osswald, H.4    Pommerenke, E.W.5    Stöhr, M.6    Volm, M.7
  • 133
    • 0013508682 scopus 로고
    • A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells
    • Pastan I, Gottesman MM, Ueda K, Lovelace E, Rotherford AW and Willingham MC: A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells. Proc Natl Acad Sci USA 85: 4486-4490, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4486-4490
    • Pastan, I.1    Gottesman, M.M.2    Ueda, K.3    Lovelace, E.4    Rotherford, A.W.5    Willingham, M.C.6
  • 135
    • 0024427595 scopus 로고
    • Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: Resistance to daunomycin-induced leukopenia
    • Galski H, Sullivan M, Willingham MC, Chin KV, Gottesman MM, Pastan I and Merlino GT: Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: Resistance to daunomycin-induced leukopenia. Mol Cell Biol 9: 4357-4363, 1989.
    • (1989) Mol Cell Biol , vol.9 , pp. 4357-4363
    • Galski, H.1    Sullivan, M.2    Willingham, M.C.3    Chin, K.V.4    Gottesman, M.M.5    Pastan, I.6    Merlino, G.T.7
  • 136
    • 0025861828 scopus 로고
    • Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection
    • Choi, K, Frommel TO, Stern RK, Perez GF, Kriegler M, Tsuruo T and Roninson IB: Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection. Proc Natl Acad Sci USA 88: 7386-7390, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7386-7390
    • Choi, K.1    Frommel, T.O.2    Stern, R.K.3    Perez, G.F.4    Kriegler, M.5    Tsuruo, T.6    Roninson, I.B.7
  • 137
    • 0001062172 scopus 로고
    • Clinical Protocols: Cancer Gene Ther 2: 67-74, 1995.
    • (1995) Cancer Gene Ther , vol.2 , pp. 67-74
  • 138
    • 0029094602 scopus 로고
    • Recombinant DNA Advisory Committee (RAC) data management report (Dec 1994)
    • ORDA Reports: Recombinant DNA Advisory Committee (RAC) data management report (Dec 1994). Hum Gene Ther 6: 535-548, 1995.
    • (1995) Hum Gene Ther , vol.6 , pp. 535-548
  • 139
    • 0031025998 scopus 로고    scopus 로고
    • Gene therapy for cancer: What have we done and where are we going?
    • Roth JA and Cristiano RJ: Gene therapy for cancer: What have we done and where are we going? (Review). J Natl Cancer Inst 89: 21-39, 1997.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 21-39
    • Roth, J.A.1    Cristiano, R.J.2
  • 140
    • 0029126007 scopus 로고
    • Transduction of NIH3T3 cells with a retrovirus carrying both human MDR1 and glutathione S-transferase pi produces broad range multidrug resistance
    • Doroshow JH, Metz MZ, Matsumoto L, Winters KA, Sakai M, Muramatsu M and Kane SE: Transduction of NIH3T3 cells with a retrovirus carrying both human MDR1 and glutathione S-transferase pi produces broad range multidrug resistance. Cancer Res 55: 4073-4078, 1995.
    • (1995) Cancer Res , vol.55 , pp. 4073-4078
    • Doroshow, J.H.1    Metz, M.Z.2    Matsumoto, L.3    Winters, K.A.4    Sakai, M.5    Muramatsu, M.6    Kane, S.E.7
  • 141
    • 0019989471 scopus 로고
    • Immunochemical detection of metallothionein in specific epithelial cells of rat organs
    • Danielson KG, Ohi S and Huang PC: Immunochemical detection of metallothionein in specific epithelial cells of rat organs. Proc Natl Acad Sci USA 79: 2301-2304, 1982.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 2301-2304
    • Danielson, K.G.1    Ohi, S.2    Huang, P.C.3
  • 142
    • 0025781307 scopus 로고
    • Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin
    • Kasahara K, Fujiwara Y, Nishio K, Ohmori Y, Sugimoto Y, Komiya K, Matsuda T and Saiyo N: Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin. Cancer Res 51: 3237-3242, 1991.
    • (1991) Cancer Res , vol.51 , pp. 3237-3242
    • Kasahara, K.1    Fujiwara, Y.2    Nishio, K.3    Ohmori, Y.4    Sugimoto, Y.5    Komiya, K.6    Matsuda, T.7    Saiyo, N.8
  • 143
  • 144
    • 0025195404 scopus 로고
    • Mammalian O6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents
    • Pegg AE: Mammalian O6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res 50: 6119-6129, 1990.
    • (1990) Cancer Res , vol.50 , pp. 6119-6129
    • Pegg, A.E.1
  • 145
    • 0022064910 scopus 로고
    • O6-alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methyl-cyclohexyl)-1-nitrourea
    • Brent TP, Houghton PJ and Houghton JA: O6-alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methyl-cyclohexyl)-1-nitrourea. Proc Natl Acad Sci USA 82: 2985-2989, 1985.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 2985-2989
    • Brent, T.P.1    Houghton, P.J.2    Houghton, J.A.3
  • 146
    • 0025941670 scopus 로고
    • Transfection and expression of human O6- Methylguanine-DNA-methyltransferase (MGMT) cDNA in Chinese hamster cells: The role of MGMT in protection against the genotoxic effects of alkylating agents
    • Kaina B, Fritz G, Mitra S and Coquerelle T: Transfection and expression of human O6-methylguanine-DNA-methyltransferase (MGMT) cDNA in Chinese hamster cells: The role of MGMT in protection against the genotoxic effects of alkylating agents. Carcinogenesis 12: 1857-1867, 1991.
    • (1991) Carcinogenesis , vol.12 , pp. 1857-1867
    • Kaina, B.1    Fritz, G.2    Mitra, S.3    Coquerelle, T.4
  • 147
    • 0027337683 scopus 로고
    • Effect of O6-benzylguanine on the sensitivity of human colon tumor xenografts to 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU)
    • Dolan ME, Pegg AE, Moschel RC and Grindey GB: Effect of O6-benzylguanine on the sensitivity of human colon tumor xenografts to 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU). Biochem Pharmacol 46: 285-290, 1993.
    • (1993) Biochem Pharmacol , vol.46 , pp. 285-290
    • Dolan, M.E.1    Pegg, A.E.2    Moschel, R.C.3    Grindey, G.B.4
  • 148
    • 0023838919 scopus 로고
    • Elevated expression of thymidylate synthase cycle genes in cisplatin-resistant human ovarian carcinoma A 2780 cells
    • Scanlon KJ and Kashani-Sabet: Elevated expression of thymidylate synthase cycle genes in cisplatin-resistant human ovarian carcinoma A 2780 cells. Proc Natl Acad Sci USA 85: 650-653, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 650-653
    • Scanlon, K.J.1    Kashani-Sabet2
  • 149
    • 0025899109 scopus 로고
    • Absence of retinoblastoma protein expression in primary non-small cell lung carcinomas
    • Xu HJ, Hu SX, Cagle PT, Moore GE and Benedict WF: Absence of retinoblastoma protein expression in primary non-small cell lung carcinomas. Cancer Res 51: 2735-2739, 1991.
    • (1991) Cancer Res , vol.51 , pp. 2735-2739
    • Xu, H.J.1    Hu, S.X.2    Cagle, P.T.3    Moore, G.E.4    Benedict, W.F.5
  • 150
    • 0018500735 scopus 로고
    • Pretherapeutic detection of tumor resistance and the results of tumour chemotherapy
    • Volm M, Wayss K, Kaufmann M and Mattern J: Pretherapeutic detection of tumor resistance and the results of tumour chemotherapy. Eur J Cancer 15: 983-993, 1979.
    • (1979) Eur J Cancer , vol.15 , pp. 983-993
    • Volm, M.1    Wayss, K.2    Kaufmann, M.3    Mattern, J.4
  • 151
    • 0021735425 scopus 로고
    • Gene amplification in cultured cells
    • Schimke RT: Gene amplification in cultured cells. Cell 37: 705-713, 1984.
    • (1984) Cell , vol.37 , pp. 705-713
    • Schimke, R.T.1
  • 152
    • 0023190752 scopus 로고
    • Heat shock proteins: Role in thermotolerance, drug resistance, and relationship to DNA topoisomerases
    • Li GC: Heat shock proteins: Role in thermotolerance, drug resistance, and relationship to DNA topoisomerases. NCI Monogr 4: 99-103, 1987.
    • (1987) NCI Monogr , vol.4 , pp. 99-103
    • Li, G.C.1
  • 153
    • 0025106538 scopus 로고
    • A typical multidrug-resistance conferred by expression of the human HSP 27 heat shock gene in Chinese hamster cells
    • Huot J, Lambert H, Roy G and Landry J: A typical multidrug-resistance conferred by expression of the human HSP 27 heat shock gene in Chinese hamster cells. Eur J Pharmacol 183: 1632-1633, 1990.
    • (1990) Eur J Pharmacol , vol.183 , pp. 1632-1633
    • Huot, J.1    Lambert, H.2    Roy, G.3    Landry, J.4
  • 154
    • 0026623042 scopus 로고
    • Response of human breast cancer cells to heat shock and chemotherapeutic drugs
    • Ciocca DR, Fuqua SAW, Lock-Lim S, Toft DO, Welch WJ and McGuire WL: Response of human breast cancer cells to heat shock and chemotherapeutic drugs. Cancer Res 52: 3648-3654, 1992.
    • (1992) Cancer Res , vol.52 , pp. 3648-3654
    • Ciocca, D.R.1    Saw, F.2    Lock-Lim, S.3    Toft, D.O.4    Welch, W.J.5    McGuire, W.L.6
  • 155
    • 0025988318 scopus 로고
    • Increased survival after treatments with anticancer agents of Chinese hamster cells expressing the human Mr 27,000 heat shock protein
    • Huot J, Roy G, Lambert H, Chretien P and Landry J: Increased survival after treatments with anticancer agents of Chinese hamster cells expressing the human Mr 27,000 heat shock protein. Cancer Res 51: 245-252, 1991.
    • (1991) Cancer Res , vol.51 , pp. 245-252
    • Huot, J.1    Roy, G.2    Lambert, H.3    Chretien, P.4    Landry, J.5
  • 156
    • 0027366354 scopus 로고
    • The small heat shock protein hsp 27 is correlated with growth and drug resistance in human breast cancer cell lines
    • Oesterreich S, Weng CN, Qui M, Hilsenbeck SG, Osborne CK and Fuqua SAW: The small heat shock protein hsp 27 is correlated with growth and drug resistance in human breast cancer cell lines. Cancer Res 53: 4443-4448, 1993.
    • (1993) Cancer Res , vol.53 , pp. 4443-4448
    • Oesterreich, S.1    Weng, C.N.2    Qui, M.3    Hilsenbeck, S.G.4    Osborne, C.K.5    Fuqua, S.A.W.6
  • 157
    • 0016836859 scopus 로고
    • Proliferation-dependent cytotoxicity of anticancer agents: A review
    • Valeriote F and van Putten L: Proliferation-dependent cytotoxicity of anticancer agents: a review. Cancer Res 3: 2619-2630, 1975.
    • (1975) Cancer Res , vol.3 , pp. 2619-2630
    • Valeriote, F.1    Van Putten, L.2
  • 158
    • 0019515510 scopus 로고
    • Differential killing efficacy of twenty antitumor drugs on proliferating and nonproliferating human tumor cells
    • Drewinko B, Patchen M, Yang LY and Barlogie B: Differential killing efficacy of twenty antitumor drugs on proliferating and nonproliferating human tumor cells. Cancer Res 41: 2328-2333, 1981.
    • (1981) Cancer Res , vol.41 , pp. 2328-2333
    • Drewinko, B.1    Patchen, M.2    Yang, L.Y.3    Barlogie, B.4
  • 159
    • 0027336491 scopus 로고
    • Mammalian G1 cyclins
    • Sherr CJ: Mammalian G1 cyclins. Cell 73: 1059-1065, 1993.
    • (1993) Cell , vol.73 , pp. 1059-1065
    • Sherr, C.J.1
  • 160
    • 0028991396 scopus 로고
    • Mutation of cell cycle regulators. Biological and clinical implications for human neoplasia
    • Cordon-Cardo C: Mutation of cell cycle regulators. Biological and clinical implications for human neoplasia (review). Am J Pathol 147: 545-560, 1995.
    • (1995) Am J Pathol , vol.147 , pp. 545-560
    • Cordon-Cardo, C.1
  • 161
    • 8244226661 scopus 로고    scopus 로고
    • Cyclin A is associated with an unfavourable outcome in patients with non-small-cell lung carcinomas
    • Volm M, Koomägi R, Mattern J and Stammler G: Cyclin A is associated with an unfavourable outcome in patients with non-small-cell lung carcinomas. Br J Cancer 75: 1774-1778, 1997.
    • (1997) Br J Cancer , vol.75 , pp. 1774-1778
    • Volm, M.1    Koomägi, R.2    Mattern, J.3    Stammler, G.4
  • 162
    • 0028307739 scopus 로고
    • Hypoxia and drug resistance
    • Teicher BA: Hypoxia and drug resistance. Cancer Metast Rev 13: 139-168, 1994.
    • (1994) Cancer Metast Rev , vol.13 , pp. 139-168
    • Teicher, B.A.1
  • 163
    • 0029135399 scopus 로고
    • Up-regulation of resistance-related proteins in human lung tumors with poor vascularization
    • Koomägi R, Mattern J and Volm M: Up-regulation of resistance-related proteins in human lung tumors with poor vascularization. Carcinogenesis 16: 2129-2133, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 2129-2133
    • Koomägi, R.1    Mattern, J.2    Volm, M.3
  • 164
    • 0030005057 scopus 로고    scopus 로고
    • Interrelationship between microvessel density, expression of VEGF and resistance to doxorubicin in non-small cell lung carcinoma
    • Volm M, Koomägi R and Mattern J: Interrelationship between microvessel density, expression of VEGF and resistance to doxorubicin in non-small cell lung carcinoma. Anticancer Res 16: 213-218, 1996.
    • (1996) Anticancer Res , vol.16 , pp. 213-218
    • Volm, M.1    Koomägi, R.2    Mattern, J.3
  • 165
    • 0028587418 scopus 로고
    • Anticancer drug resistance and inhibition of apoptosis
    • Dezoise B: Anticancer drug resistance and inhibition of apoptosis. Anticancer Res 14: 2291-2294, 1994.
    • (1994) Anticancer Res , vol.14 , pp. 2291-2294
    • Dezoise, B.1
  • 166
    • 0001929963 scopus 로고    scopus 로고
    • Apoptosis in non-small cell lung cancer as related to drug resistance and prognosis
    • Stammler G and Volm M: Apoptosis in non-small cell lung cancer as related to drug resistance and prognosis. Apoptosis 1: 95-99, 1996.
    • (1996) Apoptosis , vol.1 , pp. 95-99
    • Stammler, G.1    Volm, M.2


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