Overexpression of lung-resistance protein and increased P-glycoprotein function in acute myeloid leukaemia cells predict a poor response to chemotherapy and reduced patient survival

British Journal of Haematology

Volumn 103, Issue 4, 1998, Pages 1083-1091

  Borg, Anton G ^a   Burgess, Robert ^a   Green, Linda M ^b   Scheper, Rik J ^c   Liu Yin, John A ^a  

^a MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^b ST MARY S HOSPITAL   (United Kingdom)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Drug resistance; Leukaemia; LRP; MRP; Pgp

Indexed keywords

AMSACRINE; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; GLYCOPROTEIN P; LUNG RESISTANCE PROTEIN; MITOXANTRONE; TIOGUANINE;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

ACUTE DISEASE; ADOLESCENT; ADULT; ANTIGENS, CD34; DISEASE-FREE SURVIVAL; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; LEUKEMIA, MYELOID; MALE; MIDDLE AGED; NEOPLASM PROTEINS; P-GLYCOPROTEIN; PROGNOSIS; RETROSPECTIVE STUDIES; VAULT RIBONUCLEOPROTEIN PARTICLES;

EID: 0032430818     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.01111.x     Document Type: Article

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