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Volumn 10, Issue 3, 1996, Pages 426-433

Expression of PKC isozyme and MDR-associated genes in primary and relapsed state AML

Author keywords

Acute myelogeneous leukemia; Glutathione S transferase ; MDR1 P glycoprotein; MRP; Multidrug resistance; PKC isozymes

Indexed keywords

COMPLEMENTARY DNA; CYCLIN A; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); GLUTATHIONE TRANSFERASE; ISOENZYME; MESSENGER RNA; PROTEIN KINASE C;

EID: 0029964052     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (64)

References (58)
  • 1
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoprotein-mediated multidrug resistance
    • Endicott JA, Ling V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu Rev Biochem 1989; 58: 137-171.
    • (1989) Annu Rev Biochem , vol.58 , pp. 137-171
    • Endicott, J.A.1    Ling, V.2
  • 4
    • 0028054888 scopus 로고
    • Overexpression of rnultidrug resistance-associated protein (MRP) increases resistance to natural product drugs
    • Grant C, Valdimarsson G, Hipfner DR, Almquist KC, Cole SPC, Deeley RG. Overexpression of rnultidrug resistance-associated protein (MRP) increases resistance to natural product drugs. Cancer Res 1994; 54: 357-361.
    • (1994) Cancer Res , vol.54 , pp. 357-361
    • Grant, C.1    Valdimarsson, G.2    Hipfner, D.R.3    Almquist, K.C.4    Cole, S.P.C.5    Deeley, R.G.6
  • 5
    • 0022508033 scopus 로고
    • Altered DNA topoisomerase II activity in chinese hamster cells resistant to topoisomerase inhibitors
    • Pommier Y, Kerrigan D, Schwartz RE, Swack JA, McCurdy A. Altered DNA topoisomerase II activity in chinese hamster cells resistant to topoisomerase inhibitors. Cancer Res 1986; 46: 3075-3081.
    • (1986) Cancer Res , vol.46 , pp. 3075-3081
    • Pommier, Y.1    Kerrigan, D.2    Schwartz, R.E.3    Swack, J.A.4    McCurdy, A.5
  • 6
    • 0024372723 scopus 로고
    • Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes
    • Chung TD, Drake FH, Tan KB, Per SR, Crooke ST, Mirabelli CK. Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes. Proc Natl Acad Sci USA 1989; 86: 9431-9435.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9431-9435
    • Chung, T.D.1    Drake, F.H.2    Tan, K.B.3    Per, S.R.4    Crooke, S.T.5    Mirabelli, C.K.6
  • 7
    • 0025210084 scopus 로고
    • Decreased nuclear matrix DNA topoisomerase II in human leukemia cells resistant to VM-26 and m-AMSA
    • Fernandes DJ, Danks MK, Beck WT. Decreased nuclear matrix DNA topoisomerase II in human leukemia cells resistant to VM-26 and m-AMSA. Biochemistry 1990; 29: 4235-4241
    • (1990) Biochemistry , vol.29 , pp. 4235-4241
    • Fernandes, D.J.1    Danks, M.K.2    Beck, W.T.3
  • 8
    • 0025162113 scopus 로고
    • Reduced DNA topoisomerase II activity and drug-induced DNA cleavage activity in an adriamycin-resistant human small cell lung carcinoma cell line
    • DeJong S, Zijlstra JG, de Vries EGE, Mulder NH. Reduced DNA topoisomerase II activity and drug-induced DNA cleavage activity in an adriamycin-resistant human small cell lung carcinoma cell line. Cancer Res 1990; 50: 304-309.
    • (1990) Cancer Res , vol.50 , pp. 304-309
    • DeJong, S.1    Zijlstra, J.G.2    De Vries, E.G.E.3    Mulder, N.H.4
  • 10
    • 0027443694 scopus 로고
    • Altered topoisomerase IIα in a drug-resistant small cell lung cancer cell line selected in VP-16
    • Mirski SEL, Evans CD, Almquist KC, Slovak ML, Cole SPC. Altered topoisomerase IIα in a drug-resistant small cell lung cancer cell line selected in VP-16. Cancer Res 1993; 53: 4866-4873.
    • (1993) Cancer Res , vol.53 , pp. 4866-4873
    • Mirski, S.E.L.1    Evans, C.D.2    Almquist, K.C.3    Slovak, M.L.4    Cole, S.P.C.5
  • 11
    • 0028009810 scopus 로고
    • Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance
    • Schneider E, Horton JK, Yang CH, Nakagawa M, Cowan KH. Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance. Cancer Res 1994; 54: 152-158.
    • (1994) Cancer Res , vol.54 , pp. 152-158
    • Schneider, E.1    Horton, J.K.2    Yang, C.H.3    Nakagawa, M.4    Cowan, K.H.5
  • 12
    • 0028954441 scopus 로고
    • Relationship of DNA topoisomerase IIα and β expression to cytotoxicity of antineoplastic agents in human acute lymphoblastic leukemia cell lines
    • Brown GA, McPherson JP, Gu L, Hedley DW, Toso R, Deuchars KL, Freedman MH, Goldenberg GJ. Relationship of DNA topoisomerase IIα and β expression to cytotoxicity of antineoplastic agents in human acute lymphoblastic leukemia cell lines. Cancer Res 1995; 55: 78-82.
    • (1995) Cancer Res , vol.55 , pp. 78-82
    • Brown, G.A.1    McPherson, J.P.2    Gu, L.3    Hedley, D.W.4    Toso, R.5    Deuchars, K.L.6    Freedman, M.H.7    Goldenberg, G.J.8
  • 18
    • 0025341341 scopus 로고
    • Expression of mdr1 and mdr3 multidrug-resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporine
    • Herweijer H, Sonneveld P, Baas F, Nooter K. Expression of mdr1 and mdr3 multidrug-resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporine. J Natl Cancer Inst 1990; 82: 1133-1140.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 1133-1140
    • Herweijer, H.1    Sonneveld, P.2    Baas, F.3    Nooter, K.4
  • 19
    • 0025914062 scopus 로고
    • Multidrug resistance (mdr1) gene expression in adult acute leukemias: Correlations with treatment outcome and in vitro drug sensitivity
    • Marie JP, Zittoun R, Sikic BI. Multidrug resistance (mdr1) gene expression in adult acute leukemias: correlations with treatment outcome and in vitro drug sensitivity. Blood 1991; 78: 586-592.
    • (1991) Blood , vol.78 , pp. 586-592
    • Marie, J.P.1    Zittoun, R.2    Sikic, B.I.3
  • 21
    • 0027314191 scopus 로고
    • Expression of the multidrug resistance associated P-glycoprotein in 59 cases of de novo acute lymphoblastic leukemia: Prognostic implications
    • Goasguen JE, Dossot J-M, Fardel O, Mee FL, Gall EL, Leblay R, LePrise PY, Chaperon J, Fauchet R. Expression of the multidrug resistance associated P-glycoprotein in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications. Blood 1993; 81: 2394-2398.
    • (1993) Blood , vol.81 , pp. 2394-2398
    • Goasguen, J.E.1    Dossot, J.-M.2    Fardel, O.3    Mee, F.L.4    Gall, E.L.5    Leblay, R.6    LePrise, P.Y.7    Chaperon, J.8    Fauchet, R.9
  • 22
    • 0028945582 scopus 로고
    • Expression of mdr1, mrp, topoisomerase IIα/β and cyclin A in primary or relapsed states of acute lymphoblastic leukemias
    • Beck J, Handgretinger R, Dopfer R, Klingebiel T, Niethammer D, Gekeler V. Expression of mdr1, mrp, topoisomerase IIα/β and cyclin A in primary or relapsed states of acute lymphoblastic leukemias. Br J Haematol 1995; 89: 356-363.
    • (1995) Br J Haematol , vol.89 , pp. 356-363
    • Beck, J.1    Handgretinger, R.2    Dopfer, R.3    Klingebiel, T.4    Niethammer, D.5    Gekeler, V.6
  • 23
    • 0027164161 scopus 로고
    • Multiple pathway drug resistance
    • Mattern J, Volm M. Multiple pathway drug resistance (review). Int J Oncol 1993; 2: 557-561.
    • (1993) Int J Oncol , vol.2 , pp. 557-561
    • Mattern, J.1    Volm, M.2
  • 25
    • 0028130233 scopus 로고
    • High mdr1- and mrp-, but low topoisomerase IIα-gene expression in B-cell chronic lymphocytic leukaemias
    • Beck J, Niethammer D, Gekeler V High mdr1- and mrp-, but low topoisomerase IIα-gene expression in B-cell chronic lymphocytic leukaemias. Cancer Lett 1994; 86: 135-142.
    • (1994) Cancer Lett , vol.86 , pp. 135-142
    • Beck, J.1    Niethammer, D.2    Gekeler, V.3
  • 27
    • 0028600064 scopus 로고
    • Expression of the multidrug resistance associated protein (MRP) in acute leukemia
    • Hart SM, Ganeshaguru K, Hoffbrand AV, Prentice HG, Mehta AB. Expression of the multidrug resistance associated protein (MRP) in acute leukemia. Leukemia 1994; 8: 2163-2168.
    • (1994) Leukemia , vol.8 , pp. 2163-2168
    • Hart, S.M.1    Ganeshaguru, K.2    Hoffbrand, A.V.3    Prentice, H.G.4    Mehta, A.B.5
  • 31
    • 0027322679 scopus 로고
    • Protein kinase C isoenzymes: Divergence in signal transduction?
    • Hug H, Sarre TF. Protein kinase C isoenzymes: divergence in signal transduction? Biochem J 1993; 291: 291-343.
    • (1993) Biochem J , vol.291 , pp. 291-343
    • Hug, H.1    Sarre, T.F.2
  • 33
    • 0028900634 scopus 로고
    • Immunocytochemical localisation of eight protein kinase C isozymes over-expressed in NIH 3T3 fibroblasts
    • Goodnight J, Mischak H, Kolch W, Mushinski JF. Immunocytochemical localisation of eight protein kinase C isozymes over-expressed in NIH 3T3 fibroblasts. J Biol Chem 1995; 270: 9991-10001.
    • (1995) J Biol Chem , vol.270 , pp. 9991-10001
    • Goodnight, J.1    Mischak, H.2    Kolch, W.3    Mushinski, J.F.4
  • 34
    • 0027292678 scopus 로고
    • Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-α and -δ and not by protein kinase C-βII, -ε, -ζ, and -η
    • Mischak H, Pierce JH, Goodnight J, Kazanietz MG, Blumberg PM, Mushinski JF. Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-α and -δ and not by protein kinase C-βII, -ε, -ζ, and -η. J Biol Chem 1993; 268: 20110-20115
    • (1993) J Biol Chem , vol.268 , pp. 20110-20115
    • Mischak, H.1    Pierce, J.H.2    Goodnight, J.3    Kazanietz, M.G.4    Blumberg, P.M.5    Mushinski, J.F.6
  • 36
    • 0027439693 scopus 로고
    • Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKCα
    • Blobe GC, Sachs CW, Khan WA, Fabbro D, Stabel S, Wetsel WC, Obeid LM, Fine RL, Hannun YA. Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKCα. J Biol Chem 1993; 268: 658-664.
    • (1993) J Biol Chem , vol.268 , pp. 658-664
    • Blobe, G.C.1    Sachs, C.W.2    Khan, W.A.3    Fabbro, D.4    Stabel, S.5    Wetsel, W.C.6    Obeid, L.M.7    Fine, R.L.8    Hannun, Y.A.9
  • 37
    • 0023741594 scopus 로고
    • Expression of a P-glycoprotein gene is inducible in a multidrug-resistant human leukemia cell line
    • Gekeler V, Frese G, Diddens H, Probst H. Expression of a P-glycoprotein gene is inducible in a multidrug-resistant human leukemia cell line. Biochem Biophys Res Commun 1988; 155: 754-760.
    • (1988) Biochem Biophys Res Commun , vol.155 , pp. 754-760
    • Gekeler, V.1    Frese, G.2    Diddens, H.3    Probst, H.4
  • 38
    • 0027506202 scopus 로고
    • Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs
    • Chaudhary PM, Roninson IB. Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs. J Natl Cancer Inst 1993; 85: 632-639.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 632-639
    • Chaudhary, P.M.1    Roninson, I.B.2
  • 39
    • 0027460274 scopus 로고
    • Identification of specific sites in human P-glycoprotein phosphorylated by protein kinase
    • Chambers TC, Pohl J, Raynor RL, Kuo JF. Identification of specific sites in human P-glycoprotein phosphorylated by protein kinase. J Biol Chem 1993; 268: 4592-4595.
    • (1993) J Biol Chem , vol.268 , pp. 4592-4595
    • Chambers, T.C.1    Pohl, J.2    Raynor, R.L.3    Kuo, J.F.4
  • 41
    • 0005165123 scopus 로고
    • Protein kinase C phosphorylates topoisomerase II: Topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells
    • Sahyoun N, Wolf M, Besterman J, Hsieh T, Sander M, LeVine H III, Chang K, Cuatrecasas P. Protein kinase C phosphorylates topoisomerase II: topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells. Proc Natl Acad Sci USA 1986; 83: 1603-1607.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 1603-1607
    • Sahyoun, N.1    Wolf, M.2    Besterman, J.3    Hsieh, T.4    Sander, M.5    LeVine III, H.6    Chang, K.7    Cuatrecasas, P.8
  • 42
    • 0027512266 scopus 로고
    • Protein kinase C modulates the catalytic activity of topoisomerase II by enhancing the rate of ATP hydrolysis: Evidence for a common mechanism of regulation by phosphorylation
    • Corbett AH, Fernald AW, Osheroff N. Protein kinase C modulates the catalytic activity of topoisomerase II by enhancing the rate of ATP hydrolysis: evidence for a common mechanism of regulation by phosphorylation. Biochemistry 1993; 32: 2090-2097.
    • (1993) Biochemistry , vol.32 , pp. 2090-2097
    • Corbett, A.H.1    Fernald, A.W.2    Osheroff, N.3
  • 43
    • 0028857378 scopus 로고
    • The specific bisindolylmaleimide PKC-inhibitor GF 109203X efficiently modulates MRP-associated multiple drug resistance
    • Gekeler V, Boer R, Ise W, Sanders KH, Schächtele C, Beck J. The specific bisindolylmaleimide PKC-inhibitor GF 109203X efficiently modulates MRP-associated multiple drug resistance. Biochem Biophys Res Commun 1995; 206: 119-126.
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 119-126
    • Gekeler, V.1    Boer, R.2    Ise, W.3    Sanders, K.H.4    Schächtele, C.5    Beck, J.6
  • 45
    • 0023552030 scopus 로고
    • Structure and expression of a human class pi glutathione-S-transferase messenger RNA
    • Kano T, Sakai M, Muramatsu M. Structure and expression of a human class pi glutathione-S-transferase messenger RNA. Cancer Res 1987; 47: 5626-5631.
    • (1987) Cancer Res , vol.47 , pp. 5626-5631
    • Kano, T.1    Sakai, M.2    Muramatsu, M.3
  • 47
    • 0023629504 scopus 로고
    • Primary structures of human protein kinase C βI and βII differ only in their C-terminal sequences
    • Kubo K, Ohno S, Suzuki K. Primary structures of human protein kinase C βI and βII differ only in their C-terminal sequences. FEBS Lett 1987; 223: 138-142.
    • (1987) FEBS Lett , vol.223 , pp. 138-142
    • Kubo, K.1    Ohno, S.2    Suzuki, K.3
  • 49
    • 0026098402 scopus 로고
    • Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart
    • Bacher N, Zisman Y, Berent E, Livneh E. Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart. Mol Cell Biol 1991; 11: 126-133.
    • (1991) Mol Cell Biol , vol.11 , pp. 126-133
    • Bacher, N.1    Zisman, Y.2    Berent, E.3    Livneh, E.4
  • 50
    • 0027418818 scopus 로고
    • Molecular cloning and characterization of PKCθ, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells
    • Baier C, Telford D, Giampa L, Coggeshall KM, Baier-Bitterlich G, Isakov N, Altman A. Molecular cloning and characterization of PKCθ, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells. J Biol Chem 1993; 268: 4997-5004.
    • (1993) J Biol Chem , vol.268 , pp. 4997-5004
    • Baier, C.1    Telford, D.2    Giampa, L.3    Coggeshall, K.M.4    Baier-Bitterlich, G.5    Isakov, N.6    Altman, A.7
  • 52
    • 0028147453 scopus 로고
    • Mdr 1 gene expression in childhood acute lymphoblastic leukemias and lymphomas: A critical evaluation by four techniques
    • Brophy NA, Marie JP, Rojas VA, Warnke RA, McFall PJ, Smith SD, Sikic BI. Mdr 1 gene expression in childhood acute lymphoblastic leukemias and lymphomas: a critical evaluation by four techniques. Leukemia 1994; 8: 327-335.
    • (1994) Leukemia , vol.8 , pp. 327-335
    • Brophy, N.A.1    Marie, J.P.2    Rojas, V.A.3    Warnke, R.A.4    McFall, P.J.5    Smith, S.D.6    Sikic, B.I.7
  • 53
    • 0025751626 scopus 로고
    • Expression of protein kinase C genes in hemopoietic cells is cell-type and B cell-differentiation stage specific
    • Mischak H, Kolch W, Goodnight J, Davidson WF, Rapp U, Rose-John S, Mushinski JF. Expression of protein kinase C genes in hemopoietic cells is cell-type and B cell-differentiation stage specific. J Immunol 1991; 147: 3981-3987.
    • (1991) J Immunol , vol.147 , pp. 3981-3987
    • Mischak, H.1    Kolch, W.2    Goodnight, J.3    Davidson, W.F.4    Rapp, U.5    Rose-John, S.6    Mushinski, J.F.7
  • 54
    • 0027276906 scopus 로고
    • Influence of sequential exposure to R-verapamil or B8509-035 on rhodamine 123 accumulation in human lymphoblastoid cell lines
    • Roller E, Klumpp B, Krause J, Eichelbaum M, Schumacher K. Influence of sequential exposure to R-verapamil or B8509-035 on rhodamine 123 accumulation in human lymphoblastoid cell lines. Cancer Chem Pharmacol 1993; 32: 151-155.
    • (1993) Cancer Chem Pharmacol , vol.32 , pp. 151-155
    • Roller, E.1    Klumpp, B.2    Krause, J.3    Eichelbaum, M.4    Schumacher, K.5
  • 56
    • 0027979432 scopus 로고
    • Quantitative and qualitative aspects of topoisomerase I and IIα and β in untreated and platinum/cyclophosphamide treated malignant ovarian tumors
    • Van der Zee AGJ, de Jong S, Keith WN, Hollema H, Boonstra H, de Vries EGE. Quantitative and qualitative aspects of topoisomerase I and IIα and β in untreated and platinum/cyclophosphamide treated malignant ovarian tumors. Cancer Res 1994; 54: 749-755.
    • (1994) Cancer Res , vol.54 , pp. 749-755
    • Van Der Zee, A.G.J.1    De Jong, S.2    Keith, W.N.3    Hollema, H.4    Boonstra, H.5    De Vries, E.G.E.6
  • 57
    • 0023037085 scopus 로고
    • Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells
    • Batist G, Tulpule A, Sinha BK, Katki AG, Meyers CE, Cowan KH. Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells. J Biol Chem 1986; 261: 15544-15449.
    • (1986) J Biol Chem , vol.261 , pp. 15544-115449
    • Batist, G.1    Tulpule, A.2    Sinha, B.K.3    Katki, A.G.4    Meyers, C.E.5    Cowan, K.H.6
  • 58
    • 0026563893 scopus 로고
    • The protein kinase C-related PKC-L(η) gene product is localized in the cell nucleus
    • Greif H, Ben-Chaim J, Shimon T, Bechor E, Eldar H, Livneh E. The protein kinase C-related PKC-L(η) gene product is localized in the cell nucleus. Mol Cell Biol 1992; 12: 1304-1311.
    • (1992) Mol Cell Biol , vol.12 , pp. 1304-1311
    • Greif, H.1    Ben-Chaim, J.2    Shimon, T.3    Bechor, E.4    Eldar, H.5    Livneh, E.6


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