Pgp and MRP activities using calcein-AM are prognostic factors in adult acute myeloid leukemia patients

Blood

Volumn 91, Issue 12, 1998, Pages 4480-4488

  Legrand, Ollivier ^a   Simonin, Ghislaine ^b   Perrot, Jean Yves ^b   Zittoun, Robert ^b   Marie, Jean Pierre ^b  

^a HÔTEL DIEU   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CALCEIN; CD34 ANTIGEN; CYCLOSPORIN A; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; GLYCOPROTEIN P; IDARUBICIN; MESSENGER RNA; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN; PROBENECID;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0031864247     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.12.4480.412k28_4480_4488     Document Type: Article

References (34)

1. Marie J-P, Zittoun R, Sikic BI: Multidrug resistance (mdrl) gene expression in adult acute leukemias: Correlations with treatment outcome and in vitro drug sensitivity. Blood 78:586, 1991
2. Campos L, Guyotat D, Archimbaud E, Calmard-Oriol P, Tsuruo T, Troncy J, Treille D, Fiere D: Clinical significance of multidrug resistance P-glycoprotein expression on acute non-lymphoblastic leukemia cells at diagnosis. Blood 79:473, 1992
3. Leith CP, Kopecky KJ, Godwin J, McConnell T, Slovak ML, Ming-Chen I, Head DR, Appelbaum FR, Willman CL: Acute myeloid leukemia in the elderly: Assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group Study. Blood 89:3323, 1997
4. Hunault M, Zhou DC, Delmer A, Ramond S, Viguié F, Cadiou M, Perrot JY, Levy V, Rio B, Cymbalista F, Zittoun R, Marie J-P: Multidrug resistance (MDR1) gene expression in acute myeloid leukemia: Major prognosis significance for the in vivo drug resistance to induction treatment. Ann Hematol 74:65, 1997
5. - cases. Blood 86:2329, 1995
6. Bailly JD, Muller C, Jaffrézou JP, Demur C, Gassar G, Bordier C, Laurent G: Lack of correlation between expression and function of Pgp in acute myeloid leukemia cells. Leukemia 9:799, 1995
7. Cole SPC, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Kurz EU, Duncan AM, Deeley RG: Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 258:1650, 1992
8. Scheper RJ, Broxterman HJ, Scheffer GL, Kaaijk P, Dalton WS, van Heijningen TH, van Kalken CK, Slovak ML, de Vries EG, van der Valk P, Meijer CJLM, Pinedo HM: Overexpression of a Mr 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res 54:357, 1993
9. Zhou DC, Zittoun R, Marie J-P: expression of multidrug resistance associated protein (MRP) and multidrug resistance (MDR1) genes in acute myeloid leukemia. Leukemia 9:1661, 1995
10. List AF, Spier CS, Grogan TM, Jonhson C, Roe DJ, Greer JP, Wolff SN, Broxterman HJ, Scheffer GL, Scheper RJ, Dalton WS: Overexprression of the major vault transporter protein lung-resistance protein predicts treatment outcome in acute myeloid leukemia. Blood 87:2464, 1996
11. Homolya L, Hollo Z, Germann UA, Pastan I, Gottesman MM, Sarkadi B: Fluorescent cellular indicators are extruded by the multidrug resistance protein. J Biol Chem 268:21493, 1993
12. Feller N, Broxterman HJ, Wahrer DC, Pinedo HM: ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): No inhibition by intracellular glutathione depletion. FEES Lett 368: 385, 1995
13. Feller N, Kuiper CM, Lankelma J, Ruhdal JK, Scheper RJ, Pinedo HM, Broxterman HJ: Functional detection of MDR1/p170 and MRP/p190-mediated multidrug resistance in tumour cells by flow cytometry. Br J Cancer 72:543, 1995
14. Broxterman HJ, Sonneveld P, Feller N, Osenkoppele GJ, Währer DCR, Eekman CA, Schoester M, Lankelma J, Pinedo HM, Löwenberg B, Schuurhuis GJ: Quality control of multidrug resistance assays in adult acute leukemia: Correlation between assays for P-glycoprotein expression and activity. Blood 87:4809, 1996
15. Zhou DC, Ramond S, Viguié F, Faussat AM, Zittoun R, Marie J-P: Progressive resistance to homoharringtonine in human myeloleukemia K562 cells: Relationship to sequential emergence of MRP and MDR1 gene overexpression and MDR1 gene translation. Int J Cancer 65:365, 1996
16. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Gallon DAG, Gralnick NR Sultan C: The morphological classification of acute lymphoblastic leukaemia: Concordance among observers and clinical correlations. Br J Haematol 47:553, 1981
17. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Gallon DAG, Gralnick NR, Sultan C: Proposed revised criteria for the classification of acute myeloid leukemia. Ann Intern Med 103:620, 1985
18. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analyt Biochem 62:156, 1977
19. Legrand O, Perrot J-Y, Tang RP, Simonin G, Gurbuxani S, Zittoun R, Marie J-P: Expression of the multidrug resistance-associated protein (MRP) mRNA and protein in normal peripheral blood and bone marrow haemopoietic cells. Br J Haematol 94:23, 1996
20. Scheffer GL, Winjngaard LJ, Flens MJ, Izquierdo MA, Slovak ML, Pinedo HM, Meijer CJLM, Clevers HC, Scheper RJ: The drug resistance-related protein LRP is the human major vault protein. Nat Med 1:578, 1995
21. Noonan KE, Roninson IB: Quantitative estimation of MDR1 mRNA levels by polymerase chain reaction, in Roninson IB (ed): Molecular and Cellular Biology of Multidrug Resistance in Tumor Cells. New York, NY, Plenum, 1991, p 319
22. Beck WT, Grogan TM, Willman CL, Cordon-Cardo C, Parham DM, Kuttesch JF, Andreeff M, Bates SE, Berard CW, Boyett JM, Brophy NA, Broxterman HJ, Chan HSL, Dalton WS, Dielt M, Fojo AT, Gascoyne RD, Head D, Houghton PJ, Kumar Svrivastava D, Lehnert M, Leith CP, Paietta E, Pavelic ZP, Rimsza L, Roninson IB, Sikic BI, Twentyman PR, Warnke R, Weinstein R: Methods to detect P-glycoprotein-associated multidrug resistance in patient tumors: Consensus recommendations. Cancer Res 56:3010, 1996
23. Marie J-P, Huet S, Faussat A-M, Perrot J-Y, Chevillard S, Barbu V, Bayle C, Boutonnat J, Calvo F, Campos-Guyotat L, Colosetti P, Cazin J-L, De Cremoux P, Delvincourt C, Demur C, Drenou B, Fenneteau O, Feuillard J, Garnier-Suillerot A, Genne P, Gorisse M-C, Gosselin P, Jouault H, Lacave R, Le Calvez G, Léglise M-C, Léonce S, Manfait M, Maynadié M, Merle-Béral H, Merlin J-L, Mousseau M, Morjani H, Picard F, Pinguet F, Poncelet P, Racadot E, Raphael M, Richard B, Rossi J-F, Schlegel N, Vielh P, Zhou DC, Robert J. French Network of the Drug Resistance Intergroup, and Drug Resistance Network of Assistance Publique-Hôpitaux de Paris: Multicentric evaluation of the MDR phenotype in leukemia. Leukemia 11:1086, 1997
24. Barrand MA, Bagrij T, Neo SY: Multidrug resistance-associated protein: A protein distinct from P-glycoprotein involved in cytotoxic drug expulsion. Gen Pharmacol 28:639, 1997
25. Gollapudi S, Kim CH, Tran BN, Sangha S, Gupta S: Probenecid reverses multidrug resistance in resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells. Cancer Chemother Pharmacol 40:150, 1997
26. Maslak P, Hegewisch-Becker S, Godfrey L, Andreeff M: Flow cytometric determination of the multidrug-resistant phenotype in acute leukemia. Cytometry 17:84, 1994
27. Homolya L, Hollo M, Muller M, Mechetner EB, Sarkadi B: A new method for a quantitative assessment of P-glycoprotein-related multidrug resistance in tumour cells. Br J Cancer 73:849, 1996
28. Hollo Z, Homolya L, Hegedus T, Sarkadi B: Transport properties of the multidrug resistance-associated protein (MRP) in human rumour cells. FEBS Lett 383:99, 1996
29. Hollo Z, Homolya L, Davis CW, Sarkadi B: Calcein accumulation as a fluorometric functional assay of the multidrug transporter. Biochim Biophys Acta 1191:384, 1994
30. + acute myeloid leukemia cells. Blood 82:3157, 1993
31. Jedlitschky G, Leier I, Buchholz U, Center M, Keppler D: ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein. Cancer Res 54:4833, 1994
32. Müller M, Meijer C, Zaman GJR, Borst P, Scheper RJ, Mulder NH, de Vries EGE, Jansen PLM: Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc Natl Acad Sci USA 91:13033, 1994
33. Schneider E, Cowan KH, Bader H, Toomey S, Schwartz GN, Karp JE, Burke PJ, Kaufmann SH: Increased expression of the multidrug resistance associated protein gene in relapsed acute leukemia. Blood 85:186, 1995
34. Michieli M, Damiani D, Ermacora A, Raspadura D, Michelutti A, Grimaz S, Fanin R, Russo D, Lauria F, Masolini P, Baccarani M: P-glycoprotein (PGP) and lung resistance-related protein (LRP) expression and function in leukaemic blast cells. Br J Haematol 96:356, 1997