The vitamin D3 analogue, calcipotriol, induces sphingomyelin hydrolysis in human keratinocytes

FEBS Letters

Volumn 378, Issue 1, 1996, Pages 88-92

  Geilen, Christoph C ^a   Bektas, Meryem ^a   Wieder, Thomas ^a   Orfanos, Constantin E ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

1 ,25 Dihydroxyvitamin D3; Calcipotriol; Cell proliferation; Ceramide; Human keratinocyte; Psoriasis; Signal transduction; Sphingomyelin hydrolysis

Indexed keywords

CALCIPOTRIOL; CALCITRIOL; CERAMIDE; SPHINGOMYELIN; DERMATOLOGICAL AGENT; DRUG DERIVATIVE;

ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOCHEMISTRY; HUMAN; HUMAN CELL; KERATINOCYTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; CELL DIVISION; DRUG EFFECT; HYDROLYSIS; KINETICS; METABOLISM;

CALCITRIOL; CELL DIVISION; CERAMIDES; DERMATOLOGIC AGENTS; HUMANS; HYDROLYSIS; KERATINOCYTES; KINETICS; SPHINGOMYELINS;

EID: 0030562067     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(95)01421-7     Document Type: Article

References (30)

1. Okazaki, T., Bell, R.M. and Hannun, Y.A. (1989) J. Biol. Chem. 264, 19076-19080.
2. Okazaki, T., Bielawska, A., Bell, R.M. and Hannun, Y.A. (1990) J. Biol. Chem. 265, 15823-15831.
3. Hannun, Y.A. and Linardic, C.M. (1993) Biochim. Biophys. Acta 1154, 223-236.
4. Hannun, Y.A. (1994) J. Biol. Chem. 269, 3125-3128.
5. Hannun, Y.A. and Bell, R.M. (1989) Science 243, 500-507.
6. Obeid, L.M., Linardic, C.M., Karolak, L.A. and Hannun, Y.A. (1993) Science 259, 1769-1771.
7. Jarvis, W.D., Kolesnick, R.N., Fornari, F.A., Traylor, R.S., Gerwirtz, D.A. and Grant, S. (1994) Proc. Natl. Acad. Sci. USA 91, 73-77.
8. Bielawska, A., Linardic, C.M. and Hannun, Y.A. (1992) J. Biol. Chem. 267, 18493-18497.
9. Christophers, E. and Krüger, G.G. (1987) in: Dermatology in General Medicine (Fitzpatrick, T.D., Eisen, A.Z., Wolff, K. and Freedberg, I.M., Eds.) McGraw-Hill, New York, pp. 461-491.
10. Binderup, L. and Bramm, E. (1988) Biochem. Pharmacol. 37, 889-895.
11. Kragballe, K. and Wildfang, I.L. (1989) Skin Pharmacol. 2, 44-45.
12. Kragballe, K., Beck, H.I. and Sogaard, H. (1988) Br. J. Dermatol. 119, 223-230.
13. Boukamp, P., Petrussevska, R.T., Breitkreutz, D., Hornung, J., Markham. A. and Fusenig, N.E. (1988) J. Cell Biol. 106, 761-771.
14. Stadler, R., Müller, R. and Orfanos, C.E. (1986) Br. J. Dermatol. 114, 273-277.
15. Boyce, S.T. and Ham, R.G. (1983) J. Invest. Dermatol. 81, 33-40.
16. Ji, L., Zhang, G., Uematsu, S., Akahori, Y. and Hirabayashi, Y. (1995) FEBS Lett. 358, 211-214.
17. Bligh, E.G. and Dyer, W.J. (1959) Can. J. Biochem. Physiol. 37, 911-917.
18. Haase, R., Wieder, Th., Geilen. C.C. and Reutter, W. (1991) FEBS Lett. 288, 129-132.
19. Jayadev, S., Linardic, C.M. and Hannun, Y.A. (1994) J. Biol. Chem. 269, 5757-5763.
20. Folch, J., Lees, M. and Sloane, G.H.S. (1957) J. Biol. Chem. 226, 497-509.
21. Jones, M.J. and Murray, A.W. (1995) J. Biol. Chem. 270, 5007-5013.
22. Detmar, M., Geilen, C.C., Wieder, Th., Orfanos, C.E. and Reutter, W. (1994) J. Invest. Dermatol. 102, 490-494.
23. Geilen, C.C., Haase, R., Buchner, K., Wieder, Th., Hucho, F. and Reutter, W. (1991) Eur. J. Cancer 27, 1650-1653.
24. Kim, M.-Y., Linardic, C., Obeid, L. and Hannun, Y. (1991) J. Biol. Chem. 266, 484-489.
25. Yardley, H.J. and Summerly, R. (1981) Pharmacol. Ther. 13, 357-383.
26. Bowser, P.A. and Gray, G.M. (1978) J. Invest. Dermatol. 70, 331-335.
27. Gray, G.M. and White, R.J. (1978) J. Invest. Dermatol. 70, 336-341.
28. Tanaka, H., Abe, E. and Miyaura, C. (1982) Biochem. J. 204, 713-719.
29. Detmar, M. and Orfanos, C.E. (1990) Arch. Dermatol. Res. 282, 238-245.
30. Wakita, H., Tokura, Y., Yagi, H., Nishimura, K. Furukawa, F. and Takigawa. M. (1994) Arch. Dermatol. Res. 286, 350-354.