-
4
-
-
0032784783
-
World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: Report of the clinical advisory committee meeting - Airlie House, Virginia
-
(1999)
J Clin Oncol
, vol.17
, pp. 3835-3849
-
-
Harris, N.L.1
Jaffe, E.S.2
Diebold, J.3
-
24
-
-
0023352145
-
Low-dose ara-C in acute nonlymphocytic leukemia and myelodysplastic syndromes: A review of 20 years' experience
-
(1987)
Semin Oncol
, vol.14
, pp. 126-133
-
-
Cheson, B.D.1
Simon, R.2
-
31
-
-
10144234806
-
Topotecan, a topoisomerase I inhibitor is active in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia
-
(1996)
Blood
, vol.88
, pp. 2473-2479
-
-
Beran, M.1
Kantarjian, H.2
O'Brien, S.3
-
33
-
-
0003351994
-
A new combination chemotherapy using topotecan, fludarabine, ara-C and G-CSF for aggressive myelodysplastic syndromes and acute myelogenous leukemia in the elderly: Dose finding for topotecan study
-
(abstract 1375)
-
(1999)
Blood
, vol.94
, Issue.SUPPL. 1
-
-
Besa, E.C.1
-
38
-
-
4243956726
-
Effect of treatment with amifostine used as single agent in patients with refractory anemia on clinical outcome and serum TNFα levels
-
(abstract 1363)
-
(1999)
Blood
, vol.94
, Issue.SUPPL. 1
-
-
Hofmann, W.K.1
Seipelt, G.2
Kalina, U.3
-
43
-
-
0020032366
-
Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine
-
(1982)
J Biol Chem
, vol.257
, pp. 2041-2048
-
-
Creusot, F.1
Acs, G.2
Christman, J.K.3
-
45
-
-
0020664023
-
Effect of 5-azacytidine on differentiation and DNA methylation in human promyelocytic leukemia cells (HL-60)
-
(1983)
Cancer Res
, vol.43
, pp. 763-769
-
-
Christman, J.K.1
-
46
-
-
0027243484
-
5-aza-2'-Deoxycytidine (decitabine) and 5-azacytidine in the treatment of acute myeloid leukemias and myelodysplastic syndromes: Past, present and future trends
-
(1993)
Leukemia
, vol.7
, pp. 51-60
-
-
Pinto, A.1
Zagonel, V.2
-
59
-
-
0007625251
-
Phase I-II clinical-biological study of 5-aza-2'-deoxycytidine (5azaCdR) as a differentiation inducer in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) of the elderly
-
(abstract 767)
-
(1989)
Proc Am Soc Clin Onco
, vol.8
, pp. 197
-
-
Zagonel, V.1
Pinto, A.2
Attadia, V.3
-
66
-
-
0032516221
-
Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein
-
(1998)
Oncogene
, vol.16
, pp. 2549-2556
-
-
David, G.1
Alland, L.2
Hong, S.H.3
-
67
-
-
0032522962
-
Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARatpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia
-
(1998)
Blood
, vol.91
, pp. 2634-2642
-
-
Guidez, F.1
Ivins, S.2
Zhu, J.3
-
72
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP 2 involves a histone deacetylase complex
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
-
77
-
-
0019461053
-
Enhancement of antitumor activity of glutamine antagonists 6-diazo-5-oxo-L-norleucine and acivicin in cell culture by glutaminase-asparaginase
-
(1981)
Cancer Res
, vol.41
, pp. 1324-1328
-
-
Rosenfeld, H.1
Roberts, J.2
-
78
-
-
0020955571
-
Biochemical strategy of cancer cells and the design of chemotherapy: G.H.A. Clowes Memorial Lecture
-
(1983)
Cancer Res
, vol.43
, pp. 3466-3492
-
-
Weber, G.1
-
90
-
-
0032868044
-
Augmentation of phenylbutyrate-induced differentiation of myeloid leukemia cells using all-trans retinoic acid
-
(1999)
Leukemia
, vol.13
, pp. 1258-1265
-
-
Yu, K.H.1
Weng, L.J.2
Fu, S.3
-
93
-
-
0033566643
-
Depsipeptide (FR901228): A novel therapeutic agent with selective, in vitro activity against human B-cell chronic lymphocytic leukemia cells
-
(1999)
Blood
, vol.94
, pp. 1401-1408
-
-
Byrd, J.C.1
Shinn, C.2
Ravi, R.3
-
94
-
-
0026446246
-
Hexamethylene bisacetamide in myelodysplastic syndrome and acute myelogenous leukemia: A phase II clinical trial with a differentiation-inducing agent
-
(1992)
Blood
, vol.80
, pp. 2604-2609
-
-
Andreeff, M.1
Stone, R.2
Michaeli, J.3
-
95
-
-
0032776214
-
Cloning of the cDNA encoding phenylalanyl tRNA synthetase regulatory alpha-subunit-like protein whose expression is down-regulated during differentiation
-
(1999)
Gene
, vol.233
, pp. 13-19
-
-
Zhou, X.1
Richon, V.M.2
Ngo, L.3
-
96
-
-
0003255277
-
Drugs used in the chemotherapy of protozoan infections
-
Gilman AG, Rau TW, Nies AS, et al (eds): Goodman and Gilman's The Pharmacologic Basis of Therapeutics. New York, NY, Pergamon
-
(1990)
, pp. 1008-1018
-
-
Webster, L.T.1
-
97
-
-
0031137591
-
Delicious poison: Arsenic trioxide for the treatment of leukemia
-
letter
-
(1997)
Blood
, vol.89
, pp. 3487-3488
-
-
Kwong, Y.L.1
Todd, D.2
-
99
-
-
0030610687
-
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients
-
(1997)
Blood
, vol.89
, pp. 3354-3360
-
-
Shen, Z.X.1
Chen, G.Q.2
Ni, J.H.3
-
101
-
-
0032170898
-
Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARalpha independent manner
-
(1998)
Blood
, vol.92
, pp. 1497-1504
-
-
Wang, Z.G.1
Rivi, R.2
Delva, L.3
-
102
-
-
0030610686
-
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells
-
(1997)
Blood
, vol.89
, pp. 3345-3353
-
-
Chen, G.Q.1
Shi, X.G.2
Tang, W.3
-
107
-
-
0032910345
-
Arsenic trioxide and interferon-alpha synergize to induce cell cycle arrest and apoptosis in human T-cell lymphotropic virus type I-transformed cells
-
(1999)
Blood
, vol.93
, pp. 278-283
-
-
Bazarbachi, A.1
El-Sabban, M.E.2
Nasr, R.3
-
110
-
-
0010740572
-
In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins
-
(1996)
Blood
, vol.88
, pp. 1052-1061
-
-
Chen, G.Q.1
Zhu, J.2
Shi, X.G.3
-
113
-
-
0002511919
-
Toxic effects of metals
-
Klaassen CD (ed): Casarett and Doull's Toxicology: The Basic Science of Poisons. New York, NY, McGraw-Hill
-
(1996)
, pp. 691-698
-
-
Goyer, R.A.1
-
117
-
-
0032933610
-
Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system
-
(1999)
Blood
, vol.93
, pp. 268-277
-
-
Dai, J.1
Weinberg, R.S.2
Waxman, S.3
-
120
-
-
0033570955
-
Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: Remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients
-
(1999)
Blood
, vol.94
, pp. 3315-3324
-
-
Niu, C.1
Yan, H.2
Yu, T.3
-
122
-
-
0006373680
-
Leukocytosis and the 'retinoic acid syndrome' during induction treatment of acute promyelocytic leukemia with arsenic trioxide
-
(abstract)
-
(1999)
Blood
, vol.94
, Issue.SUPPL. 1
-
-
Camacho, L.1
Soignet, S.2
Heller, G.3
-
125
-
-
0024542411
-
UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II Purification, physico-chemical properties, structural determination and biological activities
-
(1989)
J Antibiot
, vol.42
, pp. 571-576
-
-
Takahashi, I.1
Saitoh, Y.2
Yoshida, M.3
-
127
-
-
0025998841
-
Use and specificity of staurosporine, UCN-01, and calphostin C as protein kinase inhibitors
-
(1991)
Methods Enzymol
, vol.201
, pp. 340-347
-
-
Tamaoki, T.1
-
128
-
-
0030615323
-
G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cipl/WAF1/Sdil in p53-mutated human epidermoid carcinoma A 431 cells
-
(1997)
Cancer Res
, vol.57
, pp. 1495-1501
-
-
Akiyama, T.1
Yoshida, T.2
Tsujita, T.3
-
138
-
-
0029938768
-
Blocking of glioma proliferation in vitro and in vivo and potentiating the effects of BCNU and cisplatin: UCN- 01, a selective protein kinase inhibitor
-
(1996)
J Neurosurg
, vol.84
, pp. 1024-1032
-
-
Pollack, I.F.1
Kawecki, S.2
Lazo, J.S.3
-
139
-
-
0031469395
-
Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2
-
(1997)
Mol Pharmacol
, vol.52
, pp. 1000-1009
-
-
Wang, S.1
Vrana, J.A.2
Bartimole, T.M.3
-
142
-
-
0033104319
-
Altered pharmacokinetics of a novel anticancer drug, UCN-01, caused by specific high affinity binding to alphal-acid glycoprotein in human
-
(1999)
Cancer Res
, vol.59
, pp. 1054-1060
-
-
Fuse, E.1
Tanii, H.2
Takai, K.3
-
146
-
-
0025352537
-
Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain
-
(1990)
Biochem Pharmacol
, vol.39
, pp. 1941-1949
-
-
Bai, R.1
Pettit, G.R.2
Hamel, E.3
-
147
-
-
0025183762
-
Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites
-
(1990)
J Biol Chem
, vol.265
, pp. 17141-17149
-
-
Bai, R.L.1
Pettit, G.R.2
Hamel, E.3
-
174
-
-
0027987118
-
Serum levels of soluble intercellular adhesion molecule 1 are increased in chronic B-lymphocytic leukemia and correlate with clinical stage and prognostic markers
-
(1994)
Blood
, vol.84
, pp. 3010-3016
-
-
Christiansen, I.1
Gidlof, C.2
Wallgren, A.3
-
176
-
-
0029112460
-
The effect of basic and acidic fibroblast growth factors (bFGF and aFGF) on the growth of leukemic blast progenitors in acute myelogenous leukemia
-
(1995)
Exp Hematol
, vol.23
, pp. 1030-1034
-
-
Nara, N.1
Kurokawa, H.2
Tohda, S.3
-
177
-
-
0030020056
-
Elevated intracellular level of basic fibroblast growth factor correlates with stage of chronic lymphocytic leukemia and is associated with resistance to fludarabine
-
(1996)
Blood
, vol.87
, pp. 1056-1063
-
-
Menzel, T.1
Rahman, Z.2
Calleja, E.3
-
178
-
-
0030797765
-
A high pretreatment serum vascular endothelial growth factor concentration is associated with poor outcome in non-Hodgkin's lymphoma
-
(1997)
Blood
, vol.90
, pp. 3167-3172
-
-
Salven, P.1
Teerenhovi, L.2
Joensuu, H.3
-
180
-
-
0031045135
-
Basic fibroblast growth factor (bFGF) upregulates the expression of bcl-2 in B cell chronic lymphocytic leukemia cell lines resulting in delaying apoptosis
-
(1997)
Leukemia
, vol.11
, pp. 258-265
-
-
Konig, A.1
Menzel, T.2
Lynen, S.3
-
182
-
-
0000783919
-
Marked anti-tumor effect from anti-angiogenesis (AA) therapy with thalidomide (T) in high risk refractory multiple myeloma (MM)
-
(abstract 1306)
-
(1998)
Blood
, vol.92
, Issue.SUPPL. 1
-
-
Singhal, S.1
Mehta, J.2
Eddlemon, P.3
-
184
-
-
0008317909
-
Thalidomide produces transfusion independence in patients with long-standing refractory anemias and myelodysplastic syndromes (MDS)
-
(abstract 2935)
-
(1999)
Blood
, vol.94
, Issue.SUPPL. 1
-
-
Raza, A.1
Lisak, L.2
Andrews, C.3
-
188
-
-
4243891161
-
Good response to cyclosporine therapy in patients with myelodysplastic syndromes having the HLA-DRB1*1501 allele
-
(abstract 1370)
-
(1999)
Blood
, vol.94
, Issue.SUPPL. 1
-
-
Okada, M.1
Okamoto, T.2
Yamada, S.3
-
189
-
-
0345211474
-
Unusual clinical presentation in a patient with myelodysplastic syndrome, with subsequent hematological remission and suppression of the malignant clone following treatment with cyclosporine A, erythropoietin and granulocyte colony-stimulating factor
-
(1999)
Leuk Res
, vol.23
, pp. 513-517
-
-
Samuelsson, J.1
Larfars, G.2
|